Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Latest on research on cancer prevention

Perhaps the best way to fight cancer is to prevent it from developing in the first place.

29 Nov 2007

Effects of weight, genetics and religious beliefs on prostate cancer

African-American men face an observable disadvantage versus Caucasian men when it comes to prostate cancer survival.

29 Nov 2007

The science of cancer health disparities in racial/ethnic minorities and the medically underserved

The latest biological, clinical and social research behind how cancer affects different racial and ethnic groups will be the focus of the first American Association for Cancer Research conference on the topic, entitled "The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved."

21 Nov 2007

Nanogen reissued patent for diagnosis of chronic congestive heart failure

Nanogen, Inc. has announced that it has been granted U.S. Patent No. RE39,816, which is a reissue of United States Patent No. 6,461,828, titled, "Conjunctive Analysis of Biological Marker Expression For Predicting Cardiac Mortality".

19 Nov 2007

Pre-malignant mammary lesions in dogs and humans display many of the same characteristics

...a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine.

16 Nov 2007

Kisspeptin and GPR54 may be the future of ovarian cancer treatment

Kisspeptin and its receptor GPR54 predict a favourable clinical outcome in women with ovarian carcinoma, and are specific for the clear cell carcinoma subtype, research published this week in the online open access journal, BMC Medicine, reveals.

16 Nov 2007

Biomarkers for Alzheimer's can be trusted in clinical trials

The best-established biomarkers for Alzheimer’s disease have a low natural variation over two years. The results speak for the inclusion of these biomarkers in clinical trials of novel drugs against Alzheimer’s disease.

16 Nov 2007

YKL-40 protein may play a role in severe asthma

A protein measured in a simple blood test may be a new biomarker to identify patients with the most serious form of asthma, Yale School of Medicine researchers report in the New England Journal of Medicine.

15 Nov 2007

WaferGen and University of Pittsburgh to collaborate on SmartChip

WaferGen Biosystems, Inc. has announced that it has established a research collaboration with the University of Pittsburgh Medical School to have it serve as the alpha test site for WaferGen's SmartChip Real-Time PCR System.

14 Nov 2007

Researchers image a biomarker of neurogenesis

Mirjana Maletic-Savatic, M.D., Ph.D, and co-investigators from Stony Brook University Medical Center, Brookhaven National Laboratory and Cold Spring Harbor Laboratory have discovered a way to image a biomarker of neural stem and progenitor cells (NPCs) in the living human brain.

13 Nov 2007

Research highlights important indicators of early-stage ovarian cancer

New research explains why some ovarian cancer patients are dying, while others survive, despite similar surgical and post-operative treatment.

13 Nov 2007

Cell response to stress signals predicts tumors in women with common pre-breast cancer

A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS.

13 Nov 2007

Molecular markers predict risk for invasive breast cancer years before the tumor develops

A team of scientists from the University of California San Francisco has identified distinct molecular markers that predict whether or not a woman is likely to develop subsequent invasive cancer after initial diagnosis with a noninvasive form of early breast cancer.

13 Nov 2007

Osteopontin-c is a good biomarker of breast cancer.

Researchers have identified a molecule that may be more accurate than existing biological signposts used to predict which breast cancers will develop into advanced forms of the disease.

6 Nov 2007

Vitamin A derivative associated with reduced growth in some lung cells

Treatment with a derivative of vitamin A called retinoic acid was associated with reduced lung cell growth in a group of former heavy smokers, according to a study published online October 30 in the Journal of the National Cancer Institute.

31 Oct 2007

New brain marker predicts cognitive decline and the development of Alzheimer's disease

Duke University Medical Center researchers have used imaging technology to identify a new marker that may help identify those at greatest risk for cognitive decline and the development of Alzheimer's disease.

31 Oct 2007

Children would need different medical care in wake of dirty bomb

If terrorists were to attack with a dirty bomb, medical authorities should be prepared to treat children differently than adults because their developing bodies would absorb and respond to the radiation exposure in distinct ways, according to a new study from the University of Rochester Medical Center.

31 Oct 2007