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FDA clears mobile medical app to help increase retention in recovery program for opioid use disorder

Today, the U.S. Food and Drug Administration cleared a mobile medical application (app) to help increase retention (the amount of time a patient participates) in an outpatient treatment program for individuals with opioid use disorder.

10 Dec 2018

Novel therapeutic targets based on biology of aging show promise for Alzheimer's disease

A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent and treat Alzheimer's disease, according to research published in the December 7, 2018 online issue of Neurology.

10 Dec 2018

New data from TAILORx trial confirms lack of chemo benefit regardless of race or ethnicity

An analysis of race and ethnicity data from the TAILORx clinical trial was presented at the 2018 San Antonio Breast Cancer Symposium.

10 Dec 2018

Australian researchers to study gas inhalational anaesthetic and likelihood of cancer return

Researchers at Melbourne are embarking upon a worldwide study to see if there is a risk of relapse of cancers among persons who have undergone surgeries.

9 Dec 2018

Black women with breast cancer have worse outcomes despite receiving equivalent treatments as white women

Even with equivalent treatments in women with hormone receptor-positive, HER2-negative breast cancer, black women had significantly higher breast cancer recurrence and increased overall mortality compared to white women in a large phase III clinical trial, TAILORx, according to data presented at the 2018 San Antonio Breast Cancer Symposium, held Dec. 4-8.

7 Dec 2018

Liraglutide drug associated with lower risk of cardiovascular events

Real world data from a large Nordic study shows that use of liraglutide, a drug for type 2 diabetes, is associated with a lower risk of myocardial infarction, stroke or cardiovascular death.

6 Dec 2018

Study: Chemotherapy agent did not improve survival in patients with triple-negative breast cancer

Treating patients who had early-stage triple-negative breast cancer with the chemotherapy agent capecitabine after they completed surgery and standard chemotherapy did not significantly improve disease-free or overall survival compared with observation, according to data from the randomized, phase III GEICAM/CIBOMA clinical trial presented at the 2018 San Antonio Breast Cancer Symposium, held Dec. 4-8.

6 Dec 2018

Researchers create new approach to classify patients with Alzheimer's disease

Researchers studying Alzheimer's disease have created an approach to classify patients with Alzheimer's disease, a finding that may open the door for personalized treatments.

5 Dec 2018

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Researchers at the University of Maryland School of Medicine's Maryland Psychiatric Center and Institute for Genome Sciences, along with researchers at the University of Maryland School of Pharmacy, have been awarded a collaborative five-year $1.78 million grant to study the brain-to-gut connection in schizophrenia.

5 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

A new article published today in The Lancet Oncology shows 39 percent of large B cell lymphoma patients treated with the chimeric antigen receptor T-cell therapy Yescarta remained in remission more than two years following therapy, and more than half of the patients treated remain alive.

4 Dec 2018

New study launched in Burkina Faso to test typhoid conjugate vaccine

A new study has been launched in Burkina Faso for Bharat Biotech's typhoid conjugate vaccine. It is the second clinical study underway in Africa for the vaccine and the first in West Africa.

4 Dec 2018

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient's own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.

4 Dec 2018

New strategies may improve performance of CAR-T cell therapy in treating cancer

Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego.

3 Dec 2018

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common.

3 Dec 2018

New drug combination could kill melanoma cells more effectively, study shows

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient.

3 Dec 2018

Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

Chimeric antigen receptor T-cell therapy, or CAR T, was named the 2017 Advance of the Year by the American Society of Clinical Oncology. The FDA approved two CAR T products last year for treatment of adult large B-cell lymphoma based on the exceptional patient outcomes seen in clinical trials.

3 Dec 2018

UK scientists find new way to identify patients with aggressive lymphoma

UK scientists have found a new way to identify people with the most aggressive types of lymphoma who are less likely to respond to standard drugs.

3 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Research highlights ability of Bio-Rad's ddPCR in quantifying minimal residual disease

More than 30 abstracts presented at the 60th American Society of Hematology Annual Meeting & Exposition in San Diego, December 1-4, featured research highlighting the ability of Bio-Rad's Droplet Digital PCR to provide high sensitivity and accuracy in quantifying minimal residual disease -- those remaining cancer cells after therapy that are associated with relapse -- in blood diseases such as leukemia.

3 Dec 2018

Clinical Trial News and Research

FDA clears mobile medical app to help increase retention in recovery program for opioid use disorder

Novel therapeutic targets based on biology of aging show promise for Alzheimer's disease

New data from TAILORx trial confirms lack of chemo benefit regardless of race or ethnicity

Australian researchers to study gas inhalational anaesthetic and likelihood of cancer return

Black women with breast cancer have worse outcomes despite receiving equivalent treatments as white women

Liraglutide drug associated with lower risk of cardiovascular events

Study: Chemotherapy agent did not improve survival in patients with triple-negative breast cancer

Researchers create new approach to classify patients with Alzheimer's disease

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

International study increases group of lung cancer patients who may benefit from immunotherapy

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

New study launched in Burkina Faso to test typhoid conjugate vaccine

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

New strategies may improve performance of CAR-T cell therapy in treating cancer

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

New drug combination could kill melanoma cells more effectively, study shows

Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

UK scientists find new way to identify patients with aggressive lymphoma

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Research highlights ability of Bio-Rad's ddPCR in quantifying minimal residual disease

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