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MGH researchers identify a potential method for treating fragile X syndrome

New research has identified a potential method for treating fragile X syndrome, a leading cause of autism spectrum disorders that is characterized by an inherited repeat of certain nucleotides within the DNA sequence of the FMR1 gene.

19 May 2023

Tailored revascularization strategies can help improve outcomes for patients with chronic limb-threatening ischemia

New analysis of chronic limb-threatening ischemia (CLTI) treatment outcomes was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions.

19 May 2023

BCG vaccine associated with reduced risk of Alzheimer's disease and related dementias

The Bacillus Calmette-Guérin (BCG) vaccine - which prevents tuberculosis - offers multiple beneficial effects, and it's currently a recommended therapy for non–muscle-invasive bladder cancer.

19 May 2023

Study finds socio-economic inequalities in access to novel therapies for many NSCLC patients

Novel anti-cancer therapies were not accessible to more than half of the patients in England who were diagnosed with non-small cell lung cancer, according to a new study published in the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer.

19 May 2023

High-risk heart attack patients could benefit from a long-term treatment with blood thinners

A new study examining the criteria proposed by the European Society of Cardiology (ESC) to prescribe long-term treatment with more than one blood thinner after percutaneous coronary intervention was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions.

19 May 2023

Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

A new clinical trial is testing the effectiveness of chemotherapy treatment following surgery for a subset of pancreatic cancer patients.

19 May 2023

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

Valbenazine improves chorea associated with Huntington's disease

The drug valbenazine statistically improves chorea, a movement disorder commonly associated with Huntington's disease, when compared to a placebo, according to a recent international study led by UTHealth Houston researcher Erin Furr Stimming, MD, who served as principal investigator on behalf of the KINECT-HD Huntington Study Group.

19 May 2023

"Neighborhood safety" may be key to weight loss

Feeling safe where you live may be key to weight loss, the European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May) will hear.

19 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Whole body cryostimulation: Useful "add-on" treatment for obesity

Whole body cryostimulation is a useful "add-on" treatment for obesity, research being presented at the European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May) suggests.

19 May 2023

Researchers investigate the effect of sulfur water baths on rheological blood properties

Researchers evaluated the health benefits of sulfur balneotherapy (sulfur baths) on the rheological properties of the blood of osteoarthritis (OA) patients.

19 May 2023

Comparing clinical characteristics and outcomes of critically ill COVID-19 patients with a chohort admitted to ICU for influenza pneumonia

A recent study evaluated clinical differences between critically ill COVID-19 and influenza patients.

19 May 2023

Study hints at potential risk between unhealthy low-fat diets and postmenopausal breast cancer

Research explores the relationship between low-fat dietary patterns and breast cancer risk, emphasizing the significance of overall dietary choices beyond individual foods or nutrients. The study highlights the role of macronutrient source quality in influencing health outcomes.

19 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Nearly half of all cancer patients suffer from excessive weight loss due to the loss of adipose and skeletal muscle tissues, or cachexia.

18 May 2023

Research paves the way to safer, more effective treatment for children with aggressive blood cancers

Australian nanomedicine researchers have come up with a new approach to solving a decades-old clinical problem: getting treatment drugs to act selectively on cancer cells in the body.

18 May 2023

Long-term opioid use more common among patients with rheumatic and musculoskeletal conditions

Patients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumatoid arthritis or fibromyalgia, who take these drugs for the first time, potentially at risk, suggest the findings of a research letter, published online in the Annals of the Rheumatic Diseases.

18 May 2023

Heart transplant patients receiving COVID-19 positive donor hearts may face increased mortality risk

Heart transplant recipients receiving organs from active COVID-19 positive donors may have an increased risk of death at six months and one year when compared to those receiving organs from recently recovered COVID-19 patients and COVID-19 negative patients, according to a study published today in the Journal of the American College of Cardiology.

18 May 2023

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Research paper discusses the relationship between iron deficiencies and immune tolerance in patients with inflammatory bowel disease. The study shows that high cellular iron levels fostered by pentanoate, a short-chain fatty acid produced by intestinal microbiota, are necessary for the homeostasis of regulatory T cells in the intestine, and iron deficiencies in Treg can result in lethal autoimmune disease.

17 May 2023

Therapy News and Research

MGH researchers identify a potential method for treating fragile X syndrome

Tailored revascularization strategies can help improve outcomes for patients with chronic limb-threatening ischemia

BCG vaccine associated with reduced risk of Alzheimer's disease and related dementias

Study finds socio-economic inequalities in access to novel therapies for many NSCLC patients

High-risk heart attack patients could benefit from a long-term treatment with blood thinners

Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Valbenazine improves chorea associated with Huntington's disease

"Neighborhood safety" may be key to weight loss

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Whole body cryostimulation: Useful "add-on" treatment for obesity

Researchers investigate the effect of sulfur water baths on rheological blood properties

Comparing clinical characteristics and outcomes of critically ill COVID-19 patients with a chohort admitted to ICU for influenza pneumonia

Study hints at potential risk between unhealthy low-fat diets and postmenopausal breast cancer

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Research paves the way to safer, more effective treatment for children with aggressive blood cancers

Long-term opioid use more common among patients with rheumatic and musculoskeletal conditions

Heart transplant patients receiving COVID-19 positive donor hearts may face increased mortality risk

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

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