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Model that sheds light on severe Duchenne muscular dystrophy could pave the way for new therapies

Researchers have developed an experimental model of severe Duchenne muscular dystrophy that offers insight into the disease.

26 Mar 2020

Key protein in sperm production could aid male infertility treatments

Researchers have discovered that a key protein drives sperm production, knowledge that may help infertile couples conceive.

26 Mar 2020

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Lonza is a large, multinational corporation serving the entire pharmaceutical product development and manufacturing pipeline, from non-clinical research products to final dosage and delivery solutions.

From Lonza 26 Mar 2020

Public health officials to Newsom: Lockdown won’t work without enforcement

When Gov. Gavin Newsom last week ordered nearly all 40 million Californians to stay in their homes to combat the spread of COVID-19, he set the tone for the nation, becoming the first to issue a statewide lockdown.

26 Mar 2020

Lipid aids healing of scratches on the cornea

A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.

26 Mar 2020

California isn’t testing enough children for lead, prompting legislation

In some parts of California, a higher percentage of children who were tested had elevated levels of toxic lead in their blood than in Flint, Michigan, during the height of that city's water crisis.

26 Mar 2020

Mologic and partners begin validation process for COVID-19 point-of-need diagnostic test

Mologic Ltd today announced that it has initiated early validation of COVID-19 point-of-need diagnostic tests with the Liverpool School of Tropical Medicine.

26 Mar 2020

Does acupuncture relieve migraines?

Acupuncture is the subject of a new study from China published in The BMJ in March 2020, which reports that it is capable of reducing migraine headaches more effectively than either sham acupuncture or usual care.

25 Mar 2020

Hyped claims that AI outdoes doctors at diagnosis could harm patient safety

A number of studies claim that artificial intelligence (AI) does as well or better than doctors at interpreting images and diagnosing medical conditions. However, a recent study published in The BMJ in March 2020 reveals that most of this research is flawed, and the results exaggerated. The outcome could be that the decision to adopt AI as part of patient care is based upon faulty premises, compromising the quality of patient care for millions of people.

25 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Coronavirus is not mutating rapidly, hope for vaccine development

Despite the coronavirus infection numbers skyrocketing, there is still good news. A team of scientists found that the novel coronavirus is not mutating significantly, suggesting any vaccine developed to fight SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) would remain effective in the long term.

25 Mar 2020

New app-based research program will evaluate wearable data to improve viral illness detection

The Scripps Research Translational Institute has launched an app-based research program that will analyze participants' wearable health data--including heart rates, sleep and activity levels--to more quickly detect the emergence of influenza, coronavirus and other fast-spreading viral illnesses.

25 Mar 2020

Study shows disparities in guideline-concordant treatment for NSCLC patients

Lung cancer is the leading cause of cancer-associated deaths in the United States. Non-small cell lung cancer (NSCLC), a group of lung cancers named for the kinds of cells found in the cancer, constitutes more than 80% of all lung cancer cases.

25 Mar 2020

Critical guidance to identify COVID-19 patients at risk of drug-induced sudden cardiac death

SARS-CoV-2, the virus that causes COVID-19, continues to spread, leading to more than 20,000 deaths worldwide in less than four months. Efforts are progressing to develop a COVID-19 vaccine, but it's still likely 12 to 18 months away.

25 Mar 2020

Targeting critical enzyme for sperm formation could help address male infertility

While some of our body's cells divide in a matter of hours, the process of making sperm, meiosis, alone takes about 14 days from start to finish. And fully six of those days are spent in the stage known as the pachytene, when pairs of chromosomes from an individual's mother and father align and connect.

25 Mar 2020

Researchers use ultrasound technique to accurately localize cardiac arrhythmias

Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Currently, the 12-lead electrocardiogram is the noninvasive clinical gold standard used to diagnose and localize these conditions, but it has limited accuracy, cannot provide an anatomical tool to visually localize the source of the arrhythmia, and depending on which clinician is looking at the signals, there might be some interpretation variability.

25 Mar 2020

Trump’s boast about U.S., South Korea coronavirus testing misses the mark

Boasting about his administration's response to the coronavirus crisis — and arguing the outbreak would soon be under control — President Donald Trump claimed that recent American efforts to test widely for COVID-19 surpass those of other countries.

25 Mar 2020

Despite failures, chemotherapy still promising against fatal pediatric brain cancer

The pediatric brain cancer known as diffuse intrinsic pontine glioma is almost uniformly fatal. In part, this is due to where and how it grows, forming as a diffuse net of cells in a part of the brainstem called the pons, which controls essential functions like breathing and swallowing.

25 Mar 2020

Hospital suppliers take to the skies to combat dire shortages of COVID-19 gear

Hospitals in the New York City area are turning to a private distributor to airlift millions of protective masks out of China.

25 Mar 2020

Hotter temperatures linked to bad mental health

Hot days increase the probability that an average adult in the U.S. will report bad mental health, according to a study published on March 25, 2020 in the open-access journal PLOS ONE by Mengyao Li of the University of Georgia, and colleagues.

25 Mar 2020

Research News and Research

Model that sheds light on severe Duchenne muscular dystrophy could pave the way for new therapies

Key protein in sperm production could aid male infertility treatments

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Public health officials to Newsom: Lockdown won’t work without enforcement

Lipid aids healing of scratches on the cornea

California isn’t testing enough children for lead, prompting legislation

Mologic and partners begin validation process for COVID-19 point-of-need diagnostic test

Does acupuncture relieve migraines?

Hyped claims that AI outdoes doctors at diagnosis could harm patient safety

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Coronavirus is not mutating rapidly, hope for vaccine development

New app-based research program will evaluate wearable data to improve viral illness detection

Study shows disparities in guideline-concordant treatment for NSCLC patients

Critical guidance to identify COVID-19 patients at risk of drug-induced sudden cardiac death

Targeting critical enzyme for sperm formation could help address male infertility

Researchers use ultrasound technique to accurately localize cardiac arrhythmias

Trump’s boast about U.S., South Korea coronavirus testing misses the mark

Despite failures, chemotherapy still promising against fatal pediatric brain cancer

Hospital suppliers take to the skies to combat dire shortages of COVID-19 gear

Hotter temperatures linked to bad mental health

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