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NIH researchers shed light on role of S. epidermidis toxin in bacterial sepsis

Staphylococcus epidermidis bacteria are a significant health concern for hospitalized infants, children and anyone with implanted medical devices.

2 Feb 2017

New Zika vaccine candidate shows potential to protect against virus with single dose

A new Zika vaccine candidate has the potential to protect against the virus with a single dose, according to a research team led by scientists from the Perelman School of Medicine at the University of Pennsylvania.

2 Feb 2017

Increased growth factor protects retinal blood vessels in animal models with diabetes

Researchers from the Schepens Eye Research Institute of Massachusetts Eye and Ear have shown that a slight increase in transforming growth factor beta (TGF-β), which is present in preclinical animal models with diabetic eye disease, protects retinal blood vessels from damage that commonly occurs in the early stages of the disease.

2 Feb 2017

Virulence of bacterial infections dependent on presence of cytotoxins, study reports

Beginning in the mid-1980s, an epidemic of severe invasive infections caused by Streptococcus pyogenes (S. pyogenes), also known as group A streptococcus (GAS), occurred in the United States, Europe, and elsewhere.

2 Feb 2017

New study offers insights into how antidepressants work in the brain

When they work, antidepressant medications may take weeks or months to alleviate symptoms of depression.

2 Feb 2017

New analysis reveals low incidence of liver cancer in patients with cirrhosis

Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is four percent or lower.

1 Feb 2017

Mount Sinai study characterizes genetically modified rat model of autism and intellectual disability

Researchers at The Seaver Autism Center for Research and Treatment at Mount Sinai have generated and characterized a genetically modified rat model of autism and intellectual disability, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published January 31 in the journal eLife.

31 Jan 2017

Valo Therapeutics develops novel oncolytic viral vaccines for treatment of multiple forms of cancer

A spin-out from the University of Helsinki, Valo Therapeutics is developing novel oncolytic viral vaccines for the treatment of multiple forms of cancer.

31 Jan 2017

First stem cell study could lead to development of therapy to reduce inflammation caused by CF

A 39-year-old man with cystic fibrosis (CF) made history by becoming the first person to receive human adult stem cells in a new research study that researchers hope will someday lead to the development of a therapy to reduce the inflammation and infection caused by CF.

31 Jan 2017

Mini-gut model provides clues to enterovirus infections in infants

Using immature stem cells to create a miniature model of the gut in the laboratory, researchers at Washington University School of Medicine in St. Louis and the University of Pittsburgh have determined how infection-causing enteroviruses enter the intestine.

31 Jan 2017

Researchers discover genes that could serve as therapeutic targets to reverse Rett syndrome

Researchers have uncovered 30 genes that could, one day, serve as therapeutic targets to reverse Rett syndrome, a rare neurological disorder that affects only girls and is a severe form of an autism spectrum disorder.

31 Jan 2017

Delays in availability of new treatments and incomprehensible price rises disadvantage cancer patients

Cancer patients are living longer and in many cases the disease is becoming chronic rather than acute. Access to drugs that help extend life and improve quality of life, and fair prices for those drugs are therefore essential for more and more people.

28 Jan 2017

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading.

28 Jan 2017

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector.

28 Jan 2017

Virginia Tech researchers find new strategy to prevent inflammatory bowel disease, colon cancer

Could inflammatory bowel disease and colon cancer be prevented by changing the shape of a single protein?There is an intimate link between uncontrolled inflammation in the gut associated with inflammatory bowel disease and the eventual development of colon cancer.

27 Jan 2017

Therapeutics News and Research

NIH researchers shed light on role of S. epidermidis toxin in bacterial sepsis

New Zika vaccine candidate shows potential to protect against virus with single dose

Increased growth factor protects retinal blood vessels in animal models with diabetes

Virulence of bacterial infections dependent on presence of cytotoxins, study reports

New study offers insights into how antidepressants work in the brain

New analysis reveals low incidence of liver cancer in patients with cirrhosis

Mount Sinai study characterizes genetically modified rat model of autism and intellectual disability

Valo Therapeutics develops novel oncolytic viral vaccines for treatment of multiple forms of cancer

First stem cell study could lead to development of therapy to reduce inflammation caused by CF

Mini-gut model provides clues to enterovirus infections in infants

Researchers discover genes that could serve as therapeutic targets to reverse Rett syndrome

Delays in availability of new treatments and incomprehensible price rises disadvantage cancer patients

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Virginia Tech researchers find new strategy to prevent inflammatory bowel disease, colon cancer

Bacterial by-product helps correct gut microbiome imbalance in mouse model of ALS

Researchers shed light on basis of Parkinson’s disease and other ‘synucleinopathies’

Scientists discover critical role of biological molecule in protecting against infection

Medical experts issue new clinical guidelines for managing and treating short children

Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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