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AI-powered drug discovery offers hope for cystinosis patients

Artificial intelligence is becoming increasingly important in drug discovery. Advances in the use of Big Data, learning algorithms and powerful computers have now enabled researchers at the University of Zurich (UZH) to better understand a serious metabolic disease.

14 Jul 2023

Exercise can improve quality of life and reduce hospitalizations for dialysis patients

Patients who engage in light exercise while undergoing dialysis are physically fitter and are admitted to hospital less frequently than those who do not.

14 Jul 2023

New drug could overcome resistance to CDK4/6 inhibitors in breast cancer

Brest cancer is the most common cancer in women. Among breast tumors that spread to other organs (develop metastasis), 70% belong to a variant, called luminal, whose cells are sensitive to the female sex hormones estrogen and progesterone. In fact, the tumor forms when these hormones order the cells to divide.

14 Jul 2023

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

Study highlights lack of gold standard for measuring asthma control in pediatric patients

Researchers compared questionnaires assessing asthma control measures in children in primary care.

14 Jul 2023

Macrophages may play a major role in the development of atrial fibrillation

Current treatments for atrial fibrillation (AFib), a common heart condition characterized by fast and irregular beats that can lead to stroke and heart failure, have multiple side effects and are ineffective for preventing AFib recurrence.

13 Jul 2023

Combination therapy shows promise in treating advanced ER+ breast cancer

Advanced estrogen receptor-positive (ER+) breast cancer can be especially difficult to treat. A new study by researchers at Dartmouth Cancer Center led by Todd W. Miller, PhD, shows promise in using a combination of estrogen and a PARP inhibitor (a drug that suppresses DNA damage repair), to treat this type of cancer.

13 Jul 2023

Scientists discover mechanism of cell death in people living with HIV

Professor Simona Stäger's team has made a breakthrough in the study of the human immunodeficiency virus (HIV).

13 Jul 2023

Cryo-EM reveals structure of key enzyme involved in protein production

Transfer RNAs (tRNAs) are among the most common types of RNA in a cell and are indispensable for protein production in all known organisms.

13 Jul 2023

Internet-delivered therapy reduces self-harm in young people

Self-harming behaviour in young people causes suffering and increases the risk of suicide. Researchers at Karolinska Institutet, Stockholm, and Region Stockholm have now studied if an internet-delivered emotion regulation therapy can reduce self-harm in youth.

13 Jul 2023

New mobile app aims to bridge the gap in communication for people with ASD

Researchers from the Universitat Oberta de Catalunya (UOC) and Parc Taulí University Hospital have developed a mobile application that compiles and presents valuable pieces of information and advice for people who interact with children or adults with autism spectrum disorder (ASD).

13 Jul 2023

Green tea compound may offer new treatment option for uterine fibroids

In a pre-clinical, proof-of-concept study from Johns Hopkins Medicine, researchers found that epigallocatechin gallate (EGCG), a green tea compound with powerful antioxidant properties, could be promising for both treating and preventing uterine fibroids.

13 Jul 2023

New study reveals how lung tumors develop drug resistance

Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades.

13 Jul 2023

New precision medicine trial shows promise for treating rare brain tumors

Papillary craniopharyngiomas (PCPs) are a rare type of brain tumor that cause substantial morbidity for patients.

13 Jul 2023

Pembrolizumab combination therapies effective for advanced NSCLC, study shows

While pembrolizumab is an approved treatment for patients with stage III non-small cell lung cancer (NSCLC), only some patients respond to this therapy. Treatment failure, researchers say, is often caused by differences in the tumor microenvironment.

12 Jul 2023

Study: Shift to telehealth during the pandemic did not deter people seeking mental health services

People seeking mental health services during the COVID-19 pandemic were not deterred by the widespread shift to telehealth services, according to research findings published in the Journal of Counseling & Development, a journal of the American Counseling Association.

12 Jul 2023