Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Discovery of 'tell-tale' viral signature in blood that identifies underlying viral infection

Scientists have identified a genomic "signature" in circulating blood that reveals exposure to common upper respiratory viruses, like the cold or flu, even before symptoms appear.

6 Aug 2009

Pattern of gene expression in blood provides clues to etiology of respiratory infections

Scientists have shown that they can identify and characterize an individual's response to a respiratory viral infection by examining the pattern of gene expression in their blood.

6 Aug 2009

Scientists isolate protein that affects both the expression of genes and the transport of proteins

Scientists at UC Santa Barbara have isolated a unique protein that appears to have a dual function and could lead to a "boon in medicine." The findings are published in the August issue of the Journal of Cell Biology.

6 Aug 2009

Expression Analysis launches new look

The url stays the same, but www.ExpressionAnalysis.com looks a lot different today. The redesigned website allows researchers and scientists to more easily navigate and locate the information and services they are looking for, in most cases in just one click. Additionally a revamped search tool enables users to find valuable information on a wide range of scientific topics.

6 Aug 2009

Aptamers offer unique therapeutic advantages

A novel class of drugs composed of single strands of DNA or RNA, called aptamers, can bind protein targets with a high strength and specificity and are currently in clinical development as treatments for a broad range of common diseases, as described in a comprehensive review article published online ahead of print in Oligonucleotides.

5 Aug 2009

Common food additive lecithin may help control blood lipids and reduce disease risk

Scientists at Washington University School of Medicine in St. Louis have identified a substance in the liver that helps process fat and glucose. That substance is a component of the common food additive lecithin, and researchers speculate it may one day be possible to use lecithin products to control blood lipids and reduce risk for diabetes, hypertension or cardiovascular disease using treatments delivered in food rather than medication.

31 Jul 2009

Covance enters strategic genomic services agreement with Merck

Covance has announced it has entered into a definitive agreement with Merck & Co., Inc. relating to the supply of genomic analysis services.

30 Jul 2009

Maternal exposure to nanoparticles related to neurological dysfunction in the mouse

Maternal exposure to nanoparticles of titanium dioxide (TiO2) affects the expression of genes related to the central nervous system in developing mice. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology found that mice whose mothers were injected with the nanoparticles while pregnant showed alteration in gene expression related to neurological dysfunction.

28 Jul 2009

Gene expression patterns in cancer could aid early screening and prevention

Distinctive patterns of genes turned off - or left on - in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say.

28 Jul 2009

Smoking increases likelihood that pancreatic ductal adenocarcinoma will become metastatic

Smoking has once again been implicated in the development of advanced cancer. Exposure to nicotine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, according to researchers from the Kimmel Cancer Center at Jefferson.

27 Jul 2009

New clues about the roots of neurological disease

Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion, according to new research led by St. Jude Children's Research Hospital scientists.

27 Jul 2009

Scent soothes stress

Feeling stressed? Then try savoring the scent of lemon, mango, lavender, or other fragrant plants.

26 Jul 2009

Discovery of key event in prostate cancer progression

A study led by researchers at the Ohio State University Comprehensive Cancer Center and Dana-Farber Cancer Institute reveals how late-stage, hormone-independent prostate tumors gain the ability to grow without need of hormones.

24 Jul 2009

UT Southwestern Medical Center grant aids study of lung cancer in people who never smoked

Researchers at UT Southwestern Medical Center are among an elite group of cancer scientists to share a $2 million grant to find biomarkers for lung cancer that develops in people who have never smoked.

21 Jul 2009

Discovery of new molecular pathway for targeting cancer

A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new treatments and targeted drugs using this approach.

20 Jul 2009

TGF beta blocker prevents epilepsy following traumatic brain injury

Dr. Alon Friedman, a neurosurgeon, professor and researcher at Ben-Gurion University of the Negev, working with researchers from UC Berkeley, California have identified a TGF Beta Blocker that when given to rats prevents epilepsy after brain damage, according to a new study appearing in the July 15 issue of the Journal of Neuroscience.

19 Jul 2009

Researchers map how staph infections alter immune system

Infectious disease specialists at UT Southwestern Medical Center have mapped the gene profiles of children with severe Staphylococcus aureus infections, providing crucial insight into how the human immune system is programmed to respond to this pathogen and opening new doors for improved therapeutic interventions.

14 Jul 2009