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Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.

18 Aug 2016

Study reveals crucial role of TERRA in preservation of telomeres

Despite their especially compact structure that is difficult to access, telomeres transcribe information like the rest of the DNA.

18 Aug 2016

Schizophrenia vulnerability emerged after divergence of modern humans from Neanderthals

Schizophrenia poses an evolutionary enigma. The disorder has existed throughout recorded human history and persists despite its severe effects on thought and behavior, and its reduced rates of producing offspring.

17 Aug 2016

MSU scientists show how special genes stay open to fight against infections

A new discovery at Michigan State University has revealed how special genes stay open for business, helping diagram a mechanism that plays a key role in fighting inflammation and infections.

17 Aug 2016

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Maintaining appropriate levels of proteins within cells largely relies on a cellular component called the proteasome, which degrades unneeded or defective proteins to recycle the components for the eventual assembly of new proteins.

16 Aug 2016

Latinos age more slowly than other ethnic groups, reveals UCLA study

A UCLA study is the first to show that Latinos age at a slower rate than other ethnic groups. The findings, published in the current issue of Genome Biology, may one day help scientists understand how to slow the aging process for everyone.

16 Aug 2016

Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows

Computers can be trained to be more accurate than pathologists in assessing slides of lung cancer tissues, according to a new study by researchers at the Stanford University School of Medicine.

16 Aug 2016

Mathematicians developing new statistical methods to predict bacterial epidemics

Mathematicians are now developing completely new statistical calculations on the world's fastest computers in order to be able to predict how epidemics of dangerous hospital bacteria spread.

16 Aug 2016

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.

16 Aug 2016

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients.

16 Aug 2016

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

Synthego, a leading provider of genome engineering solutions, officially launches today. Synthego’s flagship product line, CRISPRevolution, features synthetic guide RNA products designed to accelerate CRISPR/Cas9 and Cpf1 genome engineering research. CRISPRevolution is the first product line to offer economical access to fully synthetic RNA for high fidelity editing and increased precision in genome editing.

12 Aug 2016

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

Scientists at The Institute of Cancer Research, London, have identified how an inherited genetic variant, associated with an increased risk of developing the most common type of leukaemia, helps cancer cells survive. The findings could lead to new ways to target the disease.

12 Aug 2016

Scientists discover key molecule that drives regeneration in planarian stem cells

Many living creatures possess exceptional abilities that set them apart from other species. Cheetahs can run up to 60 miles per hour; ants can lift 100 times their body weight; flatworms can regrow amputated body parts.

12 Aug 2016

Study provides detailed picture of genetics underlying type 2 diabetes

The largest study of its kind into type 2 diabetes has produced the most detailed picture to date of the genetics underlying the condition.

12 Aug 2016

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Researchers have used CRISPR -- a revolutionary new genetic engineering technique -- to convert cells isolated from mouse connective tissue directly into neuronal cells.

11 Aug 2016

Novel computational analysis of prostate cancer suggests potential targets for therapy

Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and proteins that enable prostate cancer cells to proliferate and evade treatment.

11 Aug 2016

Genome News and Research

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

Study reveals crucial role of TERRA in preservation of telomeres

Schizophrenia vulnerability emerged after divergence of modern humans from Neanderthals

MSU scientists show how special genes stay open to fight against infections

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Latinos age more slowly than other ethnic groups, reveals UCLA study

Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows

Mathematicians developing new statistical methods to predict bacterial epidemics

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

Scientists discover key molecule that drives regeneration in planarian stem cells

Study provides detailed picture of genetics underlying type 2 diabetes

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Novel computational analysis of prostate cancer suggests potential targets for therapy

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

Researchers develop computational algorithm to analyze big genomic data for different cancers

Researchers develop machine-learning program that helps identify hundreds of ASD-related genes

UTA researcher to design computing tools to analyze large, complex patient data

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