Therapy News and Research

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Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Study aims to optimize radiotherapy treatment for patients with anal cancer

Reducing the dose and duration of radiotherapy treatments for anal cancer may result in fewer side effects, recent clinical trial results have shown.

15 May 2023

Dietary recommendations for cardiovascular health challenged by new evidence on saturated fatty acids' effects on LDL-C and Lp(a) levels

Researchers discussed current dietary recommendations to reduce the intake of saturated fatty acids.

15 May 2023

Use of prognostication and withdrawal of care decisions in severe traumatic brain injury

More than 40 traumatic brain injury experts were surveyed on the use of prognostication and withdrawal of care decisions in severe traumatic brain injury (TBI).

15 May 2023

Experts provide a new clinical picture of sarcopenic obesity

Proteins and weight training could help if obese patients are suffering from muscle atrophy. However, the problem is usually not recognized, according to Prof. Dr. Bischoff from the University of Hohenheim.

15 May 2023

Hormone replacement therapy for treating menopausal symptoms: Benefits and risks

Hot flashes, night sweats and sleep disturbances are common symptoms of menopause that can affect health, quality of life and work productivity.

15 May 2023

Humanized mouse model for rare genetic disease developed for the first time

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

15 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

Newly identified biomarker may predict NSCLC patients' treatment response to chemoimmunotherapy

Cutting-edge cancer treatments like immunotherapy are offering new hope for patients, often in combination with more common approaches such as chemotherapy. But determining the best treatment combination isn't always straightforward.

12 May 2023

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).

12 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

Young Geneva researcher wins SAKK Trial Network Award for clinical research on lymphoma

A young researcher from the Geneva University Hospital (HUG) and the University of Geneva (UNIGE), Dr Noémie Lang, wins the prestigious Swiss Group for Clinical Cancer Research (SAKK) Trial Network Award, with the intent to carry out a study evaluating early detection of central nervous system involvement in lymphomas.

12 May 2023

Therapy News and Research

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Newly identified genetic variant provides protection from Alzheimer's disease

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Study aims to optimize radiotherapy treatment for patients with anal cancer

Dietary recommendations for cardiovascular health challenged by new evidence on saturated fatty acids' effects on LDL-C and Lp(a) levels

Use of prognostication and withdrawal of care decisions in severe traumatic brain injury

Experts provide a new clinical picture of sarcopenic obesity

Hormone replacement therapy for treating menopausal symptoms: Benefits and risks

Humanized mouse model for rare genetic disease developed for the first time

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Newly identified biomarker may predict NSCLC patients' treatment response to chemoimmunotherapy

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Using an intracellular toolkit to map organelle bio-geography in stem cells

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Young Geneva researcher wins SAKK Trial Network Award for clinical research on lymphoma

Vector Biolabs expands viral vector manufacturing capacity and adds to QC capabilities

Targeting the hemoglobin problem in sickle cell disease using a new drug

Fatty liver promotes the spread of colorectal cancer to the liver

Short-term therapy sessions offer wonderful benefits to mothers, children in homeless shelters

Scarring to the collagen framework causes dysfunction in Duchenne muscular dystrophy

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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