Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Study: Antibody neutralizes dengue and Zika virus in mice

Brazil and other areas hardest hit by the Zika virus – which can cause babies to be born with abnormally small heads – are also home to dengue virus, which is spread by the same mosquito species.

25 Sep 2017

Triple-action antibody to be tested as HIV vaccine

Scientists from the National Institutes of Health (NIH) in collaboration with the pharmaceutical company Sanofi have engineered a three-pronged antibody that protected monkeys from two strains of Human Immunodeficiency Virus (HIV) better than the equivalent naturally occurring antibodies.

22 Sep 2017

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

Researchers design novel small antibody fragment with improved crystallizability

Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four polypeptide chains: two heavy chains and two light chains joined to form a Y-shaped molecule.

21 Sep 2017

Immune cells may play crucial role in helping the brain heal after hemorrhage or stroke

While immune cells called neutrophils are known to act as infantry in the body's war on germs, a National Institutes of Health-funded study suggests they can act as medics as well. By studying rodents, researchers showed that instead of attacking germs, some neutrophils may help heal the brain after an intracerebral hemorrhage, a form of stroke caused by ruptured blood vessels.

20 Sep 2017

Researchers propose new treatment strategy for colon cancer patients

Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. In a new study, researchers demonstrate for the first time that a previously uncharacterized protein is increased in colon cancer. The protein is immunoglobulin containing proline rich receptor-1 (IGPR-1) which was recently identified in the same laboratory as a cell adhesion molecule.

20 Sep 2017

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

In a multi-institutional collaborative study, scientists at The Wistar Institute and the Medical University of Vienna, Austria, have identified the role of tumor-infiltrating or tumor-associated B-cells ("TABs") in melanoma progression and resistance to targeted therapy.

20 Sep 2017

'Pocket' project develops new low-cost test for accurate TB detection

Tuberculosis (TB) is a major global health issue. According to the World Health Organisation (WHO), every year there are worldwide 8.8 million new active TB cases and nearly 2 million TB deaths - 5000 every day - mostly in the poorest communities of the developing world.

19 Sep 2017

$Study compares effect of two osteoporosis medicines on fractures$

Study compares effect of two osteoporosis medicines on fractures

A new treatment for osteoporosis provides major improvements in bone density and more effective protection against fractures than the current standard treatment.

19 Sep 2017

Carbohydrates on surface of malaria parasites could be key to effective vaccine

An international research team has shown for the first time that carbohydrates on the surface of malaria parasites play a critical role in malaria's ability to infect mosquito and human hosts.

18 Sep 2017

Combination treatment improves progression-free survival in patients with advanced urothelial cancer

Ramucirumab plus docetaxel improves progression-free survival in patients with advanced or metastatic urothelial cancer who have progressed on platinum-based chemotherapy, according to late-breaking results from the phase III RANGE trial presented today at the ESMO 2017 Congress in Madrid to be published in The Lancet.

14 Sep 2017

New discovery by TSRI scientists could speed efforts to develop effective HIV vaccine

Scientists at The Scripps Research Institute have made a discovery that could speed efforts to develop a successful HIV vaccine.

14 Sep 2017

Novel technology holds promise for improving accuracy of type 1 diabetes tests

Researchers from the Johns Hopkins University School of Medicine, Stanford University and the University of Florida report the development of a novel antibody detection technology that holds promise for improving the accuracy of diagnostic tests for type 1 diabetes in young children and making populationwide screening practical.

13 Sep 2017

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

The most common test strip people might think of for diagnosis is a home pregnancy test. Pregnant women have steadily increasing levels of the biomarker human chorionic gonadotropin (hCG), which is easily detectable in urine and a thin, colorful strip of antibodies will appear when hCG is present.

13 Sep 2017

Researchers overcome major stumbling blocks in developing HIV vaccine

An international team of researchers has demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV: the ability to generate immune cells that stay in circulation long enough to respond to and stop virus infection.

13 Sep 2017

Chemists examine radioactive metal complexes for tumor diagnosis and treatment

A team under the direction of chemist Prof. Dr Peter Comba is investigating radioactive metal complexes for use in the diagnosis and treatment of tumors.

12 Sep 2017

$New medication shows potential to reduce fracture risk in women with osteoporosis$

New medication shows potential to reduce fracture risk in women with osteoporosis

A new drug that boosts bone formation has been shown to reduce the risk of fracture in women with osteoporosis when compared to one of the most commonly used osteoporosis medications.

12 Sep 2017

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

Scientists at The Scripps Research Institute have found a new approach to the "reprogramming" of ordinary adult cells into stem cells.

12 Sep 2017

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

An antibody treatment reduces the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant chronic obstructive pulmonary disease (COPD), according to the results of two large international trials presented today at the European Respiratory Society International Congress in Milan, Italy, and simultaneously published in the New England Journal of Medicine.

12 Sep 2017

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

Oncology researchers studying high-risk children's cancers have identified a protein that offers a likely target for immunotherapy--harnessing the immune system in medical treatments. In cell cultures and animal models, a potent drug attached to an antibody selectively zeroes in on cancer cells without harming healthy cells.

11 Sep 2017

Antibody News and Research

Further Reading

Study: Antibody neutralizes dengue and Zika virus in mice

Triple-action antibody to be tested as HIV vaccine

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Researchers design novel small antibody fragment with improved crystallizability

Immune cells may play crucial role in helping the brain heal after hemorrhage or stroke

Researchers propose new treatment strategy for colon cancer patients

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

'Pocket' project develops new low-cost test for accurate TB detection

Study compares effect of two osteoporosis medicines on fractures

Carbohydrates on surface of malaria parasites could be key to effective vaccine

Combination treatment improves progression-free survival in patients with advanced urothelial cancer

New discovery by TSRI scientists could speed efforts to develop effective HIV vaccine

Novel technology holds promise for improving accuracy of type 1 diabetes tests

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

Researchers overcome major stumbling blocks in developing HIV vaccine

Chemists examine radioactive metal complexes for tumor diagnosis and treatment

New medication shows potential to reduce fracture risk in women with osteoporosis

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

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