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Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Researchers used a genetically engineered porcine donor to develop kidney grafts.

11 Oct 2023

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation.

11 Oct 2023

Advancing neurotoxicity research with INTEGRA pipettes

INTEGRA Biosciences has awarded 31 EVOLVE manual pipettes, GRIPTIPS® pipette tips worth US $1000, and lab accessories to the bioanalytical company DNTOX as part of its recent ‘INTEGRA supports start-ups’ competition, which ran until April 2023.

From INTEGRA Biosciences 10 Oct 2023

Fragile X syndrome may be unfolding in brain cells even before birth

Fragile X syndrome, the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later.

10 Oct 2023

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer's early stages, when it's easiest to treat.

10 Oct 2023

Study sheds light on the role of immune cells in fat tissue inflammation and obesity

Fat tissue, for as much as it's been vilified, is an incredibly complex and essential bodily organ involved in energy storage and hormone production, among other functions.

10 Oct 2023

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Non-melanoma skin cancer (NMSC) is causing a greater number of global deaths than melanoma, the more serious form of skin cancer, a new study presented today at the European Academy of Dermatology and Venerology (EADV) Congress 2023 has found.

10 Oct 2023

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

Genes may be responsible for third of complex regional pain syndrome cases. But the condition is less common in men, even though they are more likely to have the 4 genetic variations implicated in heightened risk, suggesting that there may be sex specific causes, say the researchers.

10 Oct 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Yale researchers uncover key role of protein CXCR4 in pregnancy

Immune cells play a key role during pregnancy, adjusting immune system response in a way that enables the fetus to develop while also protecting the parent and fetus from outside assaults like viruses.

10 Oct 2023

Macrophages play a central role in intestinal cell renewal, study reveals

A research team from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has now demonstrated for the first time the central role of macrophages in the renewal of intestinal cells, which sheds light on the complex interplay between immune cells and tissue regeneration.

10 Oct 2023

COVID-19 vaccine response lower in patients with lung conditions, study finds

Clinicians and researchers at National Jewish Health studied COVID vaccine effectiveness in patients with underlying lung conditions such as asthma, chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD).

10 Oct 2023

Protein antigen from a childhood vaccine can help refocus the body's immune system against cancer

A University of Massachusetts Amherst team has demonstrated in theory that a protein antigen from a childhood vaccine can be delivered into the cells of a malignant tumor to refocus the body's immune system against the cancer, effectively halting it and preventing its recurrence.

10 Oct 2023

SARS-CoV-2 RNA found in ocular tissues at autopsy, despite minimal inflammation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), infects tissues throughout the human body, including the eye.

10 Oct 2023

Liquid biopsies could be used as an early marker of immunotherapy response, study finds

Liquid biopsies are blood tests that can serially measure circulating tumor DNA (cell-free DNA that is shed into the bloodstream by dying cancer cells).

9 Oct 2023

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

The intricate control of cellular metabolism relies on the coordinated and harmonious interplay between the nucleus and mitochondria.

9 Oct 2023

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found.

9 Oct 2023

Drug combo safely decreases pancreatic cancer growth in mice

A new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel, a new study finds.

9 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Study provides evidence for combination therapy as first-line treatment for relapsed ITP

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, conducted a multicenter comprehensive retrospective analysis to assess the effectiveness and safety of primary single-agent and combination therapies in treating adult patients with relapsed immune thrombocytopenia (ITP).

9 Oct 2023

B Cell News and Research

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Advancing neurotoxicity research with INTEGRA pipettes

Fragile X syndrome may be unfolding in brain cells even before birth

New blood test could detect ovarian cancer early, improve treatment

Study sheds light on the role of immune cells in fat tissue inflammation and obesity

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

DNA aptamers: A versatile tool for regenerative medicine and beyond

Yale researchers uncover key role of protein CXCR4 in pregnancy

Macrophages play a central role in intestinal cell renewal, study reveals

COVID-19 vaccine response lower in patients with lung conditions, study finds

Protein antigen from a childhood vaccine can help refocus the body's immune system against cancer

SARS-CoV-2 RNA found in ocular tissues at autopsy, despite minimal inflammation

Liquid biopsies could be used as an early marker of immunotherapy response, study finds

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

Drug combo safely decreases pancreatic cancer growth in mice

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

Study provides evidence for combination therapy as first-line treatment for relapsed ITP

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