Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New tool for use in addressing lead poisoning

Lead in goat blood might not be on the top of your shopping list, but for U.S. medical personnel who each year perform more than 2 million human blood measurements, Standard Reference Material (SRM) 955c from the National Institute of Standards and Technology (NIST) can't be beat.

6 Aug 2007

Potential biomarker to predict acute kidney injury earlier than current tests

Clinicians currently lack advance warning of acute kidney injury (AKI) for patients where kidney injury timing is unknown.

3 Aug 2007

Jump in cancer-related clots

Blood clots are increasingly common in cancer patients, but University of Rochester Medical Center researchers have created a novel risk model that can predict, with 98 percent certainty, which patients will not get a blood clot.

3 Aug 2007

Phase II study of TroVax vaccine in patients with metastatic colorectal cancer

A therapeutic cancer vaccine has shown effectiveness when given alongside chemotherapy to patients with metastatic colorectal cancer in a phase II trial, according to researchers at Oxford BioMedica (UK) Ltd.

2 Aug 2007

Delta-9-tetrahydrocannabinol opens door for virus that causes Kaposi's sarcoma

The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply, according to a team of researchers at Harvard Medical School.

2 Aug 2007

Nimesulide delays pancreatic cancer precursors in mice

Nimesulide, a cyclooxygenase-2 (COX-2) inhibitor, delays the progression of precancerous pancreatic lesions in mice, according to researchers at David Geffen School of Medicine at UCLA.

2 Aug 2007

Recent research into HPV and cervical cancer

The development of the first vaccine for the prevention of cancer came 30 years after Harald zur Hausen first hypothesized that human papilloma virus (HPV) might be associated with cervical cancer.

1 Aug 2007

Gene expression pattern could lead to improved treatment of pediatric septic shock

A consortium of researchers headed by Cincinnati Children's Hospital Medical Center has discovered a gene expression pattern that could lead to improved diagnosis and treatment of pediatric septic shock , still a serious public health problem despite today's potent antibiotics and pediatric intensive care units.

27 Jul 2007

Merck appoints David Kelley, M.D., to key role in growing Diabetes and Obesity franchise

Merck & Co., Inc. has announced that David E. Kelley, M.D., has been named vice president, franchise integrator for Diabetes & Obesity. Dr. Kelley joins Merck after 20 years on staff at the University of Pittsburgh, where he most recently served as professor of medicine and director of the Obesity & Nutrition Research Center.

24 Jul 2007

Adult survivors of childhood leukemia exercise less putting themselves at risk for obesity

Overcoming pediatric cancer may only mark the beginning of a young survivor's lifelong battle to stay healthy.

24 Jul 2007

Gold nanorods identify metastatic tumor cells

Using a series of gold nanorods, each with its own characteristic optical signature, researchers at Purdue University have developed a method for rapidly assaying the cellular composition of breast tumors.

23 Jul 2007

Obesity a risk factor for multiple myeloma

An obese person is more likely than a lean person to develop multiple myeloma, according to researchers from Brigham and Women's Hospital, Harvard Medical School, and Harvard School of Public Health.

20 Jul 2007

Obesity a risk factor for multiple myeloma

An obese person is more likely than a lean person to develop multiple myeloma, according to researchers from Brigham and Women’s Hospital, Harvard Medical School, and Harvard School of Public Health.

19 Jul 2007

New method for early disease diagnosis

Purdue University researchers worked with the Indiana University School of Medicine to establish a technique that provides a new approach for detecting a number of genetic disorders found in infants and young children.

18 Jul 2007

Curing canine cancer - human cancer benefit

One of the major issues associated with longer life expectancy in man and his best friend is an increase in the incidence of cancer.

13 Jul 2007

Western diet increases breast cancer risk in Asian women

A study on the dietary habits of Chinese women has found that those who ate a Western diet increased their risk for breast cancer.

11 Jul 2007

Scientists identify two brain networks in Parkinson's

The disease that causes tremors, rigidity and slowed movements in a million Americans also targets another brain network that regulates cognitive thought and the ability to carry out everyday tasks.

10 Jul 2007

Researchers discover how microRNAs control protein synthesis

While most RNAs work to create, package, and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression.

10 Jul 2007

Debate on folic acid fortification

Since the institution of nationwide folic acid fortification of enriched grains in the mid 1990s, the number of infants born in the United States and Canada with neural tube defects has declined by 20 percent to 50 percent.

10 Jul 2007

Postmenopausal Asian women who eat a Western diet at greater risk of developing breast cancer

Postmenopausal Asian women who eat a "meat-sweet" or Western diet are at greater risk of developing breast cancer than those who eat a "vegetable-soy" diet, according to a new study. The findings mark the first time an association between a Western diet and breast cancer has been identified in Asian women.

10 Jul 2007