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Scientists decode genetic profile of rare inherited disorder that can cause genital ambiguity

A complete clinical and genetic profile of a rare inherited disorder, steroid 11-hydroxylase deficiency, which can cause genital masculinization in females, is being reported by an international group of researchers led by investigators at the Icahn School of Medicine at Mount Sinai.

30 Jan 2017

Scientists identify potential therapeutic solutions to combat age-related fibrosis

The wear and tear of life takes a cumulative toll on our bodies. Our organs gradually stiffen through fibrosis, which is a process that deposits tough collagen in our body tissue. Fibrosis happens little by little, each time we experience illness or injury. Eventually, this causes our health to decline.

30 Jan 2017

Scientists synthesize and evaluate mono/di-halogenated coumarins for anticancer activity

Throughout the world, many medicinal compounds are being discovered. Scientists have learnt to modify the chemical structures of active compounds so that they can improved therapeutic activity and reduced the toxicity.

30 Jan 2017

NTNU researcher uses big data to understand how immune system responds to viral attack

An enzyme found in many bacteria, including the bacterium that gives us strep throat, has given mankind a cheap and effective tool with which to edit our own genes.

30 Jan 2017

Single-molecule compounds may become basis for new antioxidant therapies

Treated particles of graphene derived from carbon nanotubes have demonstrated remarkable potential as life-saving antioxidants, but as small as they are, something even smaller had to be created to figure out why they work so well.

28 Jan 2017

Study reveals new mechanism that helps increase reductive power during high sugar intake

Animal diet has a tremendous natural variation, ranging from meat-eating carnivores to sugar-loving nectarivores. Omnivores, like humans, can adopt different types of diets and still remain healthy.

28 Jan 2017

Scientists identify key 'survival gene' that reduces mutation rates in mycobacteria

Scientists have discovered a key 'survival gene' that prevents strains of tuberculosis (TB) from mutating into drug-resistant 'superbugs'.

28 Jan 2017

Light emitted from digital screens can cause irreversible damage to eyes, research shows

The University Complutense of Madrid (UCM), one of the oldest Universities in the world, presents the results of its latest research confirming the irreversible damage to animals’ eyes caused by light emitted from digital screens.

27 Jan 2017

Researchers shed light on basis of Parkinson’s disease and other ‘synucleinopathies’

Parkinson's disease (PD) and other "synucleinopathies" are known to be linked to the misfolding of alpha-synuclein protein in neurons.

27 Jan 2017

New gene therapy for Pompe disease may replace currently available treatments

After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients.

27 Jan 2017

Chromatrap® kit shown to excel in DNA purification

Chromatrap® reports on the excellent results achieved by customers using their 96 well high throughput plates for ultra-pure DNA purification.

From Chromatrap® - Porvair Sciences Ltd 26 Jan 2017

Researchers design antibody that recognizes and destroys blood cancer stem cells

A protein-sugar molecule, CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) and the related myelodysplastic syndromes.

25 Jan 2017

IU study shows how fruit fly growth shares biochemical similarities with cancer cells

Scientists who study a molecule known to play a role in certain types of cancers and neurodegenerative disorders have a powerful new tool to study this compound due to research conducted at Indiana University.

25 Jan 2017

Caspase-2 enzyme deficiency linked to higher cancer risk

Researchers from the Centre for Cancer Biology at the University of South Australia have found that a deficiency of caspase-2 enzymes place people at a higher risk of developing tumours.

25 Jan 2017

TSRI researchers develop first stable semisynthetic single-celled organism

Life’s genetic code has only ever contained four natural bases. These bases pair up to form two “base pairs”—the rungs of the DNA ladder—and they have simply been rearranged to create bacteria and butterflies, penguins and people. Four bases make up all life as we know it.

25 Jan 2017

Study identifies key molecule that may pave way for personalized heart failure treatment

An international multicenter study has identified a molecule that will open the door to personalized treatment for heart failure.

25 Jan 2017

TSRI scientists receive $1.8 million grant to develop drug candidates for multiple diseases

Scientists from the Florida campus of The Scripps Research Institute have been awarded approximately $1.8 million from the National Institute of General Medical Sciences of the National Institutes of Health to develop a series of drug candidates for a number of diseases, including heart disease, rheumatoid arthritis and several neurodegenerative disorders.

24 Jan 2017

Penn researchers unravel missing steps involved in movement of cellular cargo

Every time a hormone is released from a cell, every time a neurotransmitter leaps across a synapse to relay a message from one neuron to another, the cell must undergo exocytosis.

24 Jan 2017

Researchers show how MPO enzyme kills pathogens without collateral tissue damage

Researchers from the University of Basel in Switzerland have clarified the role of the enzyme MPO.

24 Jan 2017

Characterizing the Brain - Cell by Cell

My group develops approaches to study cell-to-cell signaling in the brain – how the cells of the brain talk to each other. The brain is heterogeneous, probably more so than any other organ in our body, and many of its functions depend on the unique characteristics of these cells.

From Pittcon 23 Jan 2017

Enzyme News and Research

Scientists decode genetic profile of rare inherited disorder that can cause genital ambiguity

Scientists identify potential therapeutic solutions to combat age-related fibrosis

Scientists synthesize and evaluate mono/di-halogenated coumarins for anticancer activity

NTNU researcher uses big data to understand how immune system responds to viral attack

Single-molecule compounds may become basis for new antioxidant therapies

Study reveals new mechanism that helps increase reductive power during high sugar intake

Scientists identify key 'survival gene' that reduces mutation rates in mycobacteria

Light emitted from digital screens can cause irreversible damage to eyes, research shows

Researchers shed light on basis of Parkinson’s disease and other ‘synucleinopathies’

New gene therapy for Pompe disease may replace currently available treatments

Chromatrap® kit shown to excel in DNA purification

Researchers design antibody that recognizes and destroys blood cancer stem cells

IU study shows how fruit fly growth shares biochemical similarities with cancer cells

Caspase-2 enzyme deficiency linked to higher cancer risk

TSRI researchers develop first stable semisynthetic single-celled organism

Study identifies key molecule that may pave way for personalized heart failure treatment

TSRI scientists receive $1.8 million grant to develop drug candidates for multiple diseases

Penn researchers unravel missing steps involved in movement of cellular cargo

Researchers show how MPO enzyme kills pathogens without collateral tissue damage

Characterizing the Brain - Cell by Cell

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