Genes News and Research

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Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, is a leading cause of autism.

15 Sep 2021

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity.

15 Sep 2021

Single protein is a key player in two very common forms of dementia, study reveals

Dementia has many faces, and because of the wide range of ways in which it can develop and affect patients, it can be very challenging to treat.

15 Sep 2021

Genetic capacity of the gut microbiome determines weight loss success or failure

The strongest associations with weight loss success or failure – independent of BMI – are found in the genetic capacity of the gut microbiome.

15 Sep 2021

New technology offers a faster, easier and more efficient way to study gene function

Studying the role genes play on basic biology and disease is now easier, faster and more efficient, say researchers at Baylor College of Medicine.

15 Sep 2021

Flu shots and COVID-19 immunity

A new paper finds that the influenza vaccine may influence both the response to and incidence of infection by the SARS-CoV-2.

14 Sep 2021

Researchers build the ovarian environment using mouse stem cells

Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells.

14 Sep 2021

Gut microbiome can help or confer resistance to weight loss

Gut microbiota influences the ability to lose weight in humans, according to new research. The findings were published this week in mSystems, an open-access journal of the American Society for Microbiology.

14 Sep 2021

Cholesterol appears to play a key role in the development of Alzheimer’s disease

Cholesterol manufactured in the brain appears to play a key role in the development of Alzheimer's disease, new research indicates.

14 Sep 2021

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

Digital spatial profiling of individual glomeruli from HIV and COVID-19 patients

Now, a new study posted to the bioRxiv* server by scientists from the University of Washington explores the use of NanoString’s GeoMx digital spatial profiling (DSP) to investigate CG caused by HIV and SARS-Cov-2 infections.

14 Sep 2021

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

A synthetic molecular code shows promise towards improving the response of some cancer patients to immunotherapy treatments.

14 Sep 2021

Study identifies broadly neutralizing antibody panel against SARS-like viruses

A recent study describes 40 broadly neutralizing antibodies from two individuals with a history of COVID-19 who were recently immunized against the virus.

13 Sep 2021

New SARS-CoV-2 mechanism of host gene suppression

A new study finds that the viral non-coding RNA dubbed vmiR-5p, derived from the viral gene ORF7a, appears to reduce host transcription.

13 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

RNF5 protein plays an unusual role in acute myeloid leukemia, study shows

A new study led by scientists at Sanford Burnham Prebys has shown that the protein RNF5 plays an unusual role in acute myeloid leukemia (AML).

13 Sep 2021

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

13 Sep 2021

Functional impairment of HIV-specific T cells precedes aborted virus control

HIV is a master of evading the immune system, using a variety of methods to prevent the body from being able to find and kill it.

13 Sep 2021

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

A new study published in the journal Frontiers of Medicine indicated that Barrett's esophagus (BE) and gastroesophageal reflux disease (GERD) may represent novel comorbidities associated with SARS-CoV-2 disease. A previous study had estimated that in the United States, 5.6% of adults have BE, a disease where esophageal squamous mucosa gets damaged by GERD.

12 Sep 2021

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

A clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and Johns Hopkins Sidney Kimmel Comprehensive Cancer Center found that high-dose cytarabine followed by subsequent immunotherapy treatment with pembrolizumab benefited patients with resistant or relapsed acute myeloid leukemia (AML), a highly aggressive cancer.

12 Sep 2021

Genes News and Research

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Fountain of youth for the epigenome could become important in the treatment of osteoporosis

Single protein is a key player in two very common forms of dementia, study reveals

Genetic capacity of the gut microbiome determines weight loss success or failure

New technology offers a faster, easier and more efficient way to study gene function

Flu shots and COVID-19 immunity

Researchers build the ovarian environment using mouse stem cells

Gut microbiome can help or confer resistance to weight loss

Cholesterol appears to play a key role in the development of Alzheimer’s disease

Researchers explore whether cocoa supplementation can reduce aging

Digital spatial profiling of individual glomeruli from HIV and COVID-19 patients

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

Study identifies broadly neutralizing antibody panel against SARS-like viruses

New SARS-CoV-2 mechanism of host gene suppression

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

RNF5 protein plays an unusual role in acute myeloid leukemia, study shows

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

Functional impairment of HIV-specific T cells precedes aborted virus control

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

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