Genetic News and Research

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Biological underpinnings of a reproductive disorder caused by mutation of autism gene

A University of California, Riverside, study has identified the biological underpinnings of a reproductive disorder caused by the mutation of a gene.

5 Apr 2023

Antioxidant supplementation shows potential to improve male fertility

A new study discusses the benefits of antioxidant supplementation on male fertility.

4 Apr 2023

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

Researchers explored the interaction of white adipose tissue mitochondria with gut microbiota in obesity.

4 Apr 2023

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

4 Apr 2023

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

Poor quality sleep may bolster a person's genetic susceptibility to asthma, potentially doubling their risk of being diagnosed with the condition, suggests a large UK Biobank study, published in the open access journal BMJ Open Respiratory Research.

4 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

New software tool uses genetic data to improve cancer modeling technology

Lifestyle behaviors such as eating well and exercising can be significant factors in one's overall health. But the risk of developing cancer is predominantly at the whim of an individual's genetics.

4 Apr 2023

Unique brain proteins may be critical regulators of body weight

Genetic factors could contribute to up to 50-75% of the variance in body mass index, or BMI, in the population.

4 Apr 2023

Innovative approach to customize treatments for colorectal cancer

How to determine the most effective treatment for colon cancer? The response to chemotherapy varies greatly from one patient to another.

4 Apr 2023

Live attenuated nasal vaccine elicits superior immunity to SARS-CoV-2 variants in hamsters

Since the beginning of the COVID-19 pandemic, researchers have been working on mucosal vaccines that can be administered through the nose.

4 Apr 2023

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

A team led by engineers at the University of California San Diego has developed a biodegradable polymer system to treat rheumatoid arthritis, an autoimmune and inflammatory disease, by working in concert with the power of the human immune system.

4 Apr 2023

What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Researchers examined the significance of dietary lipids in the gut-brain axis of individuals with T2DM.

4 Apr 2023

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease - about a half million people in the United States alone suffer from the condition.

4 Apr 2023

Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

4 Apr 2023

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Obesity is a significant risk factor for premature mortality due to the predisposition to metabolic and cardiovascular disease. However, is this effect independent of the birth weight? A new research paper examines this aspect of adult obesity, measuring the effect of parental body mass index (BMI) and birth weight on the mortality risk.

3 Apr 2023

Study investigates vitamin C's effectiveness in treating gout and hyperuricemia

Scientists at the University of Minnesota, USA, have initiated a study entitled “the Hmong Microbiome and Gout, Obesity, Vitamin C (HMANGO-C) study” to determine the effect of vitamin C supplementation on serum urate levels in Hmong adults with or without gout. Hmong (pronounced mung) is a racial group originally from the Southwest of China.

3 Apr 2023

Spike protein could be responsible for memory loss in post-COVID-19 syndrome

Patients diagnosed with post-COVID-19 syndrome often experience cognitive and memory impairments. A new study by researchers from the Federal University of Rio de Janeiro (UFRJ) and UniRio provides insight into the mechanism behind this phenomenon.

3 Apr 2023

Study elucidates the genetics of preterm birth and pregnancy length

New knowledge of the genetic factors behind premature delivery and gestational duration has now emerged.

3 Apr 2023

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

Julia TCW, PhD, assistant professor of pharmacology & experimental therapeutics at Boston University Chobanian & Avedisian School of Medicine, has received a five-year, $3.9 million grant from the National Institutes of Health's National Institute on Aging.

3 Apr 2023

Age at menopause and hormone therapy use associated with increased risk of Alzheimer’s disease

Women are more likely than men to develop Alzheimer's disease (AD), with women making up two-thirds of the population living with AD.

3 Apr 2023

Genetic News and Research

Biological underpinnings of a reproductive disorder caused by mutation of autism gene

Antioxidant supplementation shows potential to improve male fertility

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

New software tool uses genetic data to improve cancer modeling technology

Unique brain proteins may be critical regulators of body weight

Innovative approach to customize treatments for colorectal cancer

Live attenuated nasal vaccine elicits superior immunity to SARS-CoV-2 variants in hamsters

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Study investigates vitamin C's effectiveness in treating gout and hyperuricemia

Spike protein could be responsible for memory loss in post-COVID-19 syndrome

Study elucidates the genetics of preterm birth and pregnancy length

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

Age at menopause and hormone therapy use associated with increased risk of Alzheimer’s disease

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