Immune System News and Research

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Re-trafficking proteins to defend against Salmonella infections

When humans get infected by pathogenic bacteria, the body's immune system tries to eliminate the intruders.

9 Jun 2020

Immune cell discovery could help develop new treatments for hepatitis B

For the first time, researchers at The Westmead Institute for Medical Research have identified and described a new and unique subset of human cells that are involved in the immune response against hepatitis B (HBV) infection. The discovery could help develop new treatments for HBV and inform future vaccine design.

9 Jun 2020

Researchers examine bat genome assemblies to find solution for COVID-19

While questions remain about the origin of COVID-19, many scientists now believe the virus spread to humans from bats. Two Texas Tech University researchers are now taking a closer look at whether bats also could offer a solution to the pandemic.

9 Jun 2020

New syndrome associated with SARS-CoV-2 is new and distinct from Kawasaki disease

A study on children suffering from severe inflammatory symptoms shows the condition is new and distinct from Kawasaki disease.

8 Jun 2020

Census of viral spike protein antigens could benefit development of SARS-CoV-2 therapeutics

A group of researchers has determined how different proteins associated with SARS-CoV-2 - the virus that causes COVID-19 - generate immune responses when given to rabbits as immunizations.

8 Jun 2020

Georgia State researcher receives $1.95 million NIH grant to study cause of autoimmunity

Dr. Leszek Ignatowicz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $1.95 million federal grant to study what causes autoimmunity in the human body.

8 Jun 2020

Novel compound shows promise for ANCA-associated vasculitis

ANCA-associated vasculitis (AAV) is a systemic disease involving the formation of special autoantibodies (so-called anti-neutrophil cytoplasmic antibodies/ANCA) and vascular inflammation.

8 Jun 2020

Tocilizumab in COVID-19 patients on mechanical ventilation

Now, a new study by researchers from the University of Michigan and published on the online preprint server medRxiv* in June 2020 shows that the cytokine inhibitor tocilizumab could have a favorable effect on survival in the most severely infected patients who require mechanical ventilation. This needs to be confirmed by clinical trials.

7 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

People suffering from rheumatoid arthritis with increased disease activity are more often affected by thrombosis.

5 Jun 2020

Kidney impairment significantly higher among hospitalized COVID-19 patients

Germany was not hit as hard by the SARS-CoV-2 pandemic as many other European countries. The reason for this is that the wave of infection reached Germany later, that the authorities were warned by the situation in Italy and Spain and at an early stage ordered a lockdown and conducted extensive testing.

5 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

T cells can counteract dangerous phenomenon of mosquito-borne viruses

Every year, more than 68,000 people end up with a clinical case of Japanese encephalitis. One in four of these patients will die. The mosquito-borne virus, which is most common in Southeast Asia, also causes severe neurological damage and psychiatric disorders.

5 Jun 2020

New research focuses on protein-coding gene's role in inflammatory bowel disease

A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside.

4 Jun 2020

New technology to monitor anti-drug antibodies in MS patients may have potential for COVID-19 testing

A new study led by Queen Mary University of London has demonstrated the effectiveness of using a novel light technology to monitor the presence of anti-drug antibodies in the treatment of multiple sclerosis, which can lead to drug resistance and treatment failure.

4 Jun 2020

Intranasal delivery of MSC-EVs shows promise for treating Alzheimer's disease

In the search for a cure for Alzheimer's disease, mesenchymal stem cells and their derived extracellular vesicles (MSC-EVs) offer much promise, thanks to their protective and anti-inflammatory properties.

4 Jun 2020

Study says vitamin-magnesium combo may reduce severity of COVID-19 in seniors

The COVID-19 pandemic that began in late December 2019 has spread to over 188 countries and territories, causing over 6.5 million cases and 385,000 deaths. With no effective therapeutic COVID-19 drug or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in sight, researchers are exploring different strategies to limit its spread and mortality.

4 Jun 2020

Hesperos’ immune system-on-a-chip emulates immune reactions for tissue damage and acute inflammation

Hesperos Inc., pioneers of the Human-on-a-Chip in vitro system, today announced the publication of a new peer-reviewed publication that describes how the company’s technology can be used to investigate immune responses following treatment with biological therapeutics for multi-organ systemic diseases, including cancer, infectious diseases and inflammatory disorders.

4 Jun 2020

AFFiRiS announces preclinical results of monoclonal antibody mAB C6-17 in Huntington's

AFFiRiS, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies, today announced that detailed preclinical results with its monoclonal antibody mAB C6-17 to treat Huntington's Disease were published in the peer-reviewed journal Neurobiology of Disease.

3 Jun 2020

Tumors cause disruption of the immune system throughout the body, study finds

Cancer treatment has advanced with the advent of immunotherapies that, in some cancers, can overcome tumors' ability to evade the immune system by suppressing local immune responses.

3 Jun 2020

Immune System News and Research

Re-trafficking proteins to defend against Salmonella infections

Immune cell discovery could help develop new treatments for hepatitis B

Researchers examine bat genome assemblies to find solution for COVID-19

New syndrome associated with SARS-CoV-2 is new and distinct from Kawasaki disease

Census of viral spike protein antigens could benefit development of SARS-CoV-2 therapeutics

Georgia State researcher receives $1.95 million NIH grant to study cause of autoimmunity

Novel compound shows promise for ANCA-associated vasculitis

Tocilizumab in COVID-19 patients on mechanical ventilation

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

Kidney impairment significantly higher among hospitalized COVID-19 patients

GMU researchers studying effect of cannabidiol on exosome release

T cells can counteract dangerous phenomenon of mosquito-borne viruses

New research focuses on protein-coding gene's role in inflammatory bowel disease

New technology to monitor anti-drug antibodies in MS patients may have potential for COVID-19 testing

Intranasal delivery of MSC-EVs shows promise for treating Alzheimer's disease

Study says vitamin-magnesium combo may reduce severity of COVID-19 in seniors

Hesperos’ immune system-on-a-chip emulates immune reactions for tissue damage and acute inflammation

AFFiRiS announces preclinical results of monoclonal antibody mAB C6-17 in Huntington's

Tumors cause disruption of the immune system throughout the body, study finds

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