Central Nervous System News and Research

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MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Francesca Marassi, PhD, professor and chair of biophysics at the Medical College of Wisconsin (MCW), has been awarded a five-year, $13 million program project grant (PPG) by the National Institutes of Health (NIH) to study misplaced calcification in the eyes and brains of patients suffering from age-related macular degeneration (AMD) and Alzheimer's disease (AD).

18 Jul 2023

Study highlights the potential of cell replacement therapy for Huntington's disease

New research appearing in the journal Nature Biotechnology answers important questions about the viability of treatments that seek to replace diseased and aged cells in the central nervous system with healthy ones.

17 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

A team led by researchers at the Mechanisms of Inherited Kidney Disorders (MIKADO) group at the University of Zurich (Zurich, Switzerland) has used Insilico Medicine's generative artificial intelligence (AI) target discovery engine, PandaOmics, to identify actionable drug targets for the lysosomal storage disease cystinosis and to validate them in preclinical models of the disease.

14 Jul 2023

New study reveals mast cells' surprising role in allergy-related avoidance behavior

Researchers showed that mast cells and IgE are the key orchestrators of antigen-specific avoidance.

14 Jul 2023

Study uncovers pathogenic variants in the chromatin modifier EZH1 as the cause of neurodevelopmental disorders

Study identified pathogenic variants in the EZH1 as a cause of neurodevelopmental disorders.

14 Jul 2023

New precision medicine trial shows promise for treating rare brain tumors

Papillary craniopharyngiomas (PCPs) are a rare type of brain tumor that cause substantial morbidity for patients.

13 Jul 2023

Scientists identify signal essential for blood-brain barrier formation

What makes the vital layer of protective cells around the brain and spinal cord - the blood-brain barrier - more or less permeable has been one of the more mystifying questions in neuroscience.

12 Jul 2023

New technique could help identify rare genetic disorders while preserving privacy

Macquarie University researchers have demonstrated a new way of linking personal records and protecting privacy. The first application is in identifying cases of rare genetic disorders. There are many other potential applications across society.

10 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

Tick season is here: How to avoid ticks

It's tick season now and researchers from the University of Agder in Norway shed light on the myths and facts about these parasites.

7 Jul 2023

Quantum medicine: the way forward?

Study examines how quantum physics can contribute to medicine.

7 Jul 2023

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Regular physical exercise, such as resistance training, can prevent Alzheimer's disease, or at least delay the appearance of symptoms, and serves as a simple and affordable therapy for Alzheimer's patients.

3 Jul 2023

Myelin can be harmful to axons in multiple sclerosis

Multiple sclerosis (MS) is a serious neurological disease that usually causes permanent disability. Approximately 2.9 million people are affected worldwide, 240,000 in Germany alone.

30 Jun 2023

WHO to declare artificial sweetener aspartame as possible carcinogen

The World Health Organization recently indicated that aspartame will likely be declared a “possible carcinogen to humans.”

29 Jun 2023

Understanding the biological effects of SARS-CoV-2 persistence in children

Researchers analyzed the most recent knowledge about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

29 Jun 2023

New study reveals alarming cognitive impairments in long COVID patients

Persistent COVID-19 symptoms can lead to cognitive deficits in recovered patients. This systematic review highlights the need for further research and interventions to address long-term cognitive impairments.

28 Jun 2023

Looking into the future: infant visual preference for mother's face predicts emotional resilience

Investigated the trajectories of infant visual preference for the mother's face and how these are related to the development.

26 Jun 2023

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

A new study in rats suggests that xylazine, the active ingredient in a non-opioid veterinary tranquilizer not approved for human use, can worsen the life-threatening effects of opioids.

21 Jun 2023

Central Nervous System News and Research

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Study highlights the potential of cell replacement therapy for Huntington's disease

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

New study reveals mast cells' surprising role in allergy-related avoidance behavior

Study uncovers pathogenic variants in the chromatin modifier EZH1 as the cause of neurodevelopmental disorders

New precision medicine trial shows promise for treating rare brain tumors

Scientists identify signal essential for blood-brain barrier formation

New technique could help identify rare genetic disorders while preserving privacy

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Tick season is here: How to avoid ticks

Quantum medicine: the way forward?

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Myelin can be harmful to axons in multiple sclerosis

WHO to declare artificial sweetener aspartame as possible carcinogen

Understanding the biological effects of SARS-CoV-2 persistence in children

New study reveals alarming cognitive impairments in long COVID patients

Looking into the future: infant visual preference for mother's face predicts emotional resilience

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

Event guide: The 7th CNS Drug Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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