Central Nervous System News and Research

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Cure Mito Foundation releases the first-of-its-kind online resource about Leigh syndrome

The Cure Mito Foundation, a parent-led organization dedicated to advancing research and treatments for Leigh syndrome, has launched the first-of-its-kind online resource about Leigh syndrome, the most common type of pediatric mitochondrial disease.

5 Jun 2023

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Three clinical trials led by researchers at The University of Texas MD Anderson Cancer Center demonstrated positive results from the targeted therapy erdafitinib for patients with multiple tumor types harboring FGFR alterations.

5 Jun 2023

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

Immune system's ability to respond to spinal cord injuries diminishes with age, study suggests

New research suggests that the immune system's ability to respond to spinal cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

2 Jun 2023

New insights into how axons grow could lead to effective therapies for blindness, paralysis

Injuries to the nerves can blind or paralyze because adult nerve cells don't regenerate their connections. Now, a team of UConn School of Medicine researchers report in Development that at least a small population of nerve cells exist in everyone that could be coaxed to regrow, potentially restoring sight and movement.

31 May 2023

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

Newborn babies who experience low levels of oxygen in their body tissues (hypoxia) due to sleep apnea, for example, tend to develop respiratory problems and hypertension (high blood pressure) in adulthood, and these problems may persist for the rest of their lives.

31 May 2023

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

This new article publication from Acta Pharmaceutica Sinica B, discusses click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries.

31 May 2023

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

To commemorate World Multiple Sclerosis (MS) Day, we speak to Dr. Cameron McAlpine about his latest research that sought to understand better the proteins and signals that act as messengers between brain and immune cells in MS.

30 May 2023

Two key physiological systems found to be involved in high-salt-induced hypertension and dementia

Dementia is defined as the loss of cognitive functioning - including thinking, remembering, and reasoning - and is very prevalent in Japan.

29 May 2023

Exploring the long-term risk of major adverse cardiovascular events following ischemic stroke and transient ischemic attack

The risk of major adverse cardiovascular events following transient ischemic attack or ischemic stroke.

25 May 2023

Immune system’s ability to respond to spinal cord injuries reduces with age, research suggests

New research suggests that the immune system’s ability to respond to spinal-cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

25 May 2023

Microplastics in the digestive tract of seabirds alters gut microbiome, finds study

Scientists have been worried about the potential harms of microplastics for years. These small plastic particles less than 5 mm in length have been found everywhere because of plastic pollution - from the Earth's deep oceans to remote regions in Antarctica, and even the seafood we eat. But, are microplastics really harmful?

25 May 2023

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

Epstein-Barr virus (EBV) has a significant role in the development of multiple sclerosis (MS), with evidence linking EBV infection to increased MS risk and immune dysregulation. Understanding the mechanisms underlying this connection is crucial for advancing MS therapies and prevention strategies.

24 May 2023

New strategies to improve the transition from school to work for young people with disabilities

A deeper level and different kind of coordination, collaboration, and cooperation are needed to narrow the gap in employment opportunities between youth and young adults with and without disabilities.

23 May 2023

Cancer researchers join together to fight lethal childhood brain cancer

Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC have joined a Children's National Hospital effort to treat deadly brain tumors with ultrahigh frequency sound waves.

22 May 2023

Blood vessel abnormalities in the eye could drive Alzheimer's disease

Blood vessel abnormalities in the eye are a major factor in the progression of Alzheimer's disease, according to research from Cedars-Sinai investigators published in the peer-reviewed journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

22 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Combining generative AI and quantum computing to accelerate drug discovery

Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it combined two rapidly developing technologies, quantum computing and generative AI, to explore lead candidate discovery in drug development and successfully demonstrated the potential advantages of quantum generative adversarial networks in generative chemistry.

19 May 2023

Long-term ketogenic diet boosts survival rates in advanced cancer patients

Long-term ketogenic diet shows improved survival rates in cancer patients, with a significantly better overall survival for those following the diet for ≥12 months. Promising results for cancer therapy.

18 May 2023

Post-COVID condition varies by variant and vaccination status

Research investigates the post-COVID-19 condition, analyzing its profiles based on viral variants and vaccination status. Understanding these profiles can aid in personalized patient care.

17 May 2023

Central Nervous System News and Research

Cure Mito Foundation releases the first-of-its-kind online resource about Leigh syndrome

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Immune system's ability to respond to spinal cord injuries diminishes with age, study suggests

New insights into how axons grow could lead to effective therapies for blindness, paralysis

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Two key physiological systems found to be involved in high-salt-induced hypertension and dementia

Exploring the long-term risk of major adverse cardiovascular events following ischemic stroke and transient ischemic attack

Immune system’s ability to respond to spinal cord injuries reduces with age, research suggests

Microplastics in the digestive tract of seabirds alters gut microbiome, finds study

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

New strategies to improve the transition from school to work for young people with disabilities

Cancer researchers join together to fight lethal childhood brain cancer

Blood vessel abnormalities in the eye could drive Alzheimer's disease

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Combining generative AI and quantum computing to accelerate drug discovery

Long-term ketogenic diet boosts survival rates in advanced cancer patients

Post-COVID condition varies by variant and vaccination status

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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