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Serological antibody response to SARS-CoV-2 infection at a population level

The scientists in this study used pooled convalescent serum to examine the serologic response in a population at risk of infection.

6 Jan 2022

Booster dose elicits cross-reactive humoral immunity against SARS-CoV-2 Delta and Omicron variants

Researchers determine the cross-reactivity of the SARS-CoV-2 spike glycoprotein-induced antibodies before and after a third SARS-CoV-2 vaccine dose.

5 Jan 2022

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

Exploring vaccine-induced cellular immunity against SARS-CoV-2 Omicron variant

In a new study, researchers determined CD8+ and CD4+ T cell responses against the SARS-CoV-2 Omicron variant in 51 individuals vaccinated with the messenger ribonucleic acid (mRNA)-based Pfizer and adenovirus vector-based Johnson & Johnson vaccines.

5 Jan 2022

Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources

Sino Biological, Inc. (SZSE: 301047) has recently deposited reagents for the Omicron variant, including recombinant proteins to Spike and Nucleocapsid, and antibody products to BEI Resources, a central repository for reagents to support infectious disease research.

From Sino Biological Inc. 4 Jan 2022

NAbs activity against SARS-CoV-2 variants, including Omicron, in an elderly vaccinated cohort

Researchers investigate the neutralizing antibody activity against different variants of SARS-CoV-2 in fully immunized elderly individuals.

3 Jan 2022

TriSb92 as a potential inhibitor against SARS-CoV-2 variants including Omicron

New findings indicate that TriSb92 is a potent inhibitor of SARS-CoV-2 infection targeting a conserved site in the RBD of the spike, which is insensitive for immune escape mutations found in the relevant variants of concern, including Omicron

31 Dec 2021

At least 3 exposures to vaccine or virus needed for minimum protection against SARS-CoV-2 Omicron

Researchers determine the serum neutralizing and binding activity against the SARS-CoV-2 Omicron variant in individuals with different levels of immunity.

29 Dec 2021

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

A new study found that the presence of a subset of antibodies with broad neutralizing activities against all circulating variants of concern in the three-dose vaccines' memory B-derived antibody repertoire suggests that the Omicron/future variants infection may elicit selective and rapid recall of humoral responses, conferring secondary protection directed by memory etched in the immune system.

29 Dec 2021

Pre-existing immunity against influenza can lower SARS-CoV-2 infection burden and spread

A recent study by a team of European researchers demonstrated how antibodies induced by currently circulating influenza A H1N1 strains can cross-react with the important part of the SARS-CoV-2 spike glycoprotein that interacts with the human cell receptor. Their paper is currently available on the medRxiv* preprint server while it undergoes peer review.

28 Dec 2021

Extended interval between second and third vaccination beneficial against SARS-CoV-2 Omicron variant

A new study proposes a multi-boost vaccine strategy with a longer duration between the second and third dose, as that would be beneficial in acquiring immunity against severely mutated SARS-CoV-2 variants.

22 Dec 2021

Broad neutralization of SARS-CoV-2 spike protein by an unconventional antibody fragment

A new preprint research paper posted to the bioRxiv* server examines the nature and effects of the spike mutations and identifies a vulnerable point that could help develop broad-spectrum protection against circulating variants.

21 Dec 2021

Receptor binding of SARS-CoV-2 Omicron variant compared to other variants

Researchers compared the binding of the new SARS-CoV-2 VOC Omicron’s RBD and ACE2 receptor with the original Wuhan SARS-CoV-2 strain and other VOCs such as Beta and Delta.

15 Dec 2021

Containing a Nipah virus outbreak amidst the COVID-19 pandemic

A new study deals with a single case of Nipah virus that occurred in 2021, with no discoverable chain of transmission, apparently ending with the death of the index patient in Kerala.

15 Dec 2021

Providing quick & efficient CRO services with Sino Biological

In this interview, News-Medical talks to Dr. Lin Yutao, head of project management at Sino Biological, about the work she does and how Sino provides quick and efficient recombinant CRO services.

From Sino Biological Inc. 15 Dec 2021

SARS-CoV-2 patients exhibit high specialized pro-resolving molecule serum levels

In a new study, researchers compared the serum levels of bioactive lipids in a cohort of 50 in-patients who had confirmed symptomatic SARS-CoV-2 infection with that of a control group.

14 Dec 2021

Vaccinated seropositive individuals are able to induce high anti-spike SIgA responses

Results of a new study show that the induction of anti-SARSCoV-2 spike saliva SIgA antibodies after vaccination is independent of the gender or type of vaccine received.

14 Dec 2021

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

A new study published on the bioRxiv preprint server has hypothesized that T cell receptors (TCR) repertoire can measure the response to vaccines, as it would identify the TCR of clones that respond to the vaccination.

13 Dec 2021

Novel assay using finger-prick samples provides COVID-19 vaccine efficacy data

Researchers estimate vaccine efficacy over a period post-vaccination using quantitative antibody assay on finger-prick blood samples.

13 Dec 2021

Cellular properties of SARS-CoV-2 spike protein RBD in virus-infected African green monkey kidney epithelial cells

Researchers from the Biological Defence Programme of Singapore have investigated six of these antibodies.

13 Dec 2021

ELISA News and Research

Serological antibody response to SARS-CoV-2 infection at a population level

Booster dose elicits cross-reactive humoral immunity against SARS-CoV-2 Delta and Omicron variants

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

Exploring vaccine-induced cellular immunity against SARS-CoV-2 Omicron variant

Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources

NAbs activity against SARS-CoV-2 variants, including Omicron, in an elderly vaccinated cohort

TriSb92 as a potential inhibitor against SARS-CoV-2 variants including Omicron

At least 3 exposures to vaccine or virus needed for minimum protection against SARS-CoV-2 Omicron

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

Pre-existing immunity against influenza can lower SARS-CoV-2 infection burden and spread

Extended interval between second and third vaccination beneficial against SARS-CoV-2 Omicron variant

Broad neutralization of SARS-CoV-2 spike protein by an unconventional antibody fragment

Receptor binding of SARS-CoV-2 Omicron variant compared to other variants

Containing a Nipah virus outbreak amidst the COVID-19 pandemic

Providing quick & efficient CRO services with Sino Biological

SARS-CoV-2 patients exhibit high specialized pro-resolving molecule serum levels

Vaccinated seropositive individuals are able to induce high anti-spike SIgA responses

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

Novel assay using finger-prick samples provides COVID-19 vaccine efficacy data

Cellular properties of SARS-CoV-2 spike protein RBD in virus-infected African green monkey kidney epithelial cells

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