Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

Antibodies aren't the only immune cells needed to fight off COVID-19 - T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine.

27 May 2021

Which biomarkers can help predict adverse outcomes in COVID-19?

A team of researchers has conducted a systematic review to identify laboratory factors that can predict the risk of severe and critical COVID-19 as well as associated mortality rates. The team – from institutions in India and the USA – recently published their findings in the Journal of Clinical Medicine Research.

24 May 2021

Study shows how human bodies develop from a single cell

New insights into how our bodies come into being from a single cell have been generated by researchers at the Wellcome Sanger Institute, the Wellcome-MRC Cambridge Stem Cell Institute and the University of Cambridge.

21 May 2021

Blocking TGFβ1 could improve hematopoiesis in AML patients, indicates study

Bone marrow failure due to acute myeloid leukemia (AML) is a significant factor behind the disease's high rate of morbidity and mortality. Previous studies in mice suggest that AML cells inhibit healthy hematopoietic (blood) stem and progenitor cells (HSPC).

20 May 2021

Study validates predictive model for identifying pediatric patients at risk for developing blood clots

Monroe Carell Jr. Children's Hospital at Vanderbilt has launched a study to determine the impact of a predictive model for identifying pediatric patients at risk for developing blood clots or venous thromboembolisms (VTEs).

19 May 2021

Machine learning technique detects epigenetic drivers of cancers

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease.

10 May 2021

Esophageal cancers turn on ancient viral DNA hidden in our genome

Scientists have discovered that many esophageal cancers turn on ancient viral DNA that was embedded in our genome hundreds of millions of years ago.

10 May 2021

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

St. Jude Children's Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature Genetics.

7 May 2021

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

Researchers have identified a gene expressed in children with acute myeloid leukemia (AML) that could serve as a new immunotherapy treatment target, according to a new study published today in Blood Advances, a journal of the American Society of Hematology.

5 May 2021

Study uncovers protein 'signature' of severe COVID-19

Researchers at Massachusetts General Hospital have identified the protein "signature" of severe COVID-19, which they describe in a new study published in Cell Reports Medicine.

4 May 2021

Cancer researchers receive $3 million NCI grant to study cognitive dysfunction after chemotherapy

Cancer researchers at the University of Pittsburgh School of Medicine and Indiana University received a five-year, $3 million grant from the National Cancer Institute (NCI) to study cognitive dysfunction after chemotherapy.

4 May 2021

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

New research published in the Centers for Disease Control and Prevention’s journal Emerging Infectious Diseases has confirmed the emergence of a new SARS-CoV-2 variant called HMN.19B from the viral clade 19B in France. The 19B viral clade — which includes the D614G variant — was prevalent in late 2019 but had since been rarely observed since early 2020 because of newer viral clades.

3 May 2021

Study evaluates first tumor-uninformed ctDNA assay to detect residual cancer cells after treatment

After patients with cancer undergo surgery to remove a tumor and sometimes additional chemotherapy, tools are used to identify patients at highest risk of recurrence.

30 Apr 2021

Quality improvement program improves depression screening among cancer patients

Depression screening among cancer patients improved by 40 percent to cover more than 90 percent of patients under a quality improvement program launched by a multidisciplinary team at UT Southwestern Medical Center and Southwestern Health Resources.

29 Apr 2021

Guidance on diagnosis and management of cerebral venous sinus thrombosis after a COVID-19 vaccine

Last Friday, the Centers for Disease Control and Prevention and the U.S. Food & Drug Administration lifted the pause in administration of the Johnson & Johnson (Janssen) COVID-19 vaccine in the U.S.

29 Apr 2021

Cognitive outcomes in survivors of childhood cancers have been largely understudied

In a new study led by Yale Cancer Center, researchers report many survivors of childhood cancers receive systemic therapies associated with cognitive effects and chronic health conditions that may impact long-term cognitive outcomes with downstream effects on education, employment, and income.

23 Apr 2021

Artificial intelligence helps identify new key-lock pairs against coronavirus

The human immune defense is based on the ability of white blood cells to accurately identify disease-causing pathogens and to initiate a defense reaction against them.

23 Apr 2021

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

In a study by Yale Cancer Center, researchers report on the discovery of a common mechanism that promotes both autoimmune diseases and blood cancers, including the blood diseases Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL).

19 Apr 2021

Study shows adverse outcomes associated with use of more blood thinners

More blood thinners aren't automatically better, another study confirms. A new publication in JAMA Internal Medicine focuses on the minimal pros and the concerning cons of combining a daily aspirin with a drug from the newer class of anticoagulants that include apixaban, dabigatran, edoxaban and rivaroxaban.

19 Apr 2021

Hematology News and Research

Further Reading

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

Which biomarkers can help predict adverse outcomes in COVID-19?

Study shows how human bodies develop from a single cell

Blocking TGFβ1 could improve hematopoiesis in AML patients, indicates study

Study validates predictive model for identifying pediatric patients at risk for developing blood clots

Machine learning technique detects epigenetic drivers of cancers

Esophageal cancers turn on ancient viral DNA hidden in our genome

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

Study uncovers protein 'signature' of severe COVID-19

Cancer researchers receive $3 million NCI grant to study cognitive dysfunction after chemotherapy

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

Study evaluates first tumor-uninformed ctDNA assay to detect residual cancer cells after treatment

Quality improvement program improves depression screening among cancer patients

Guidance on diagnosis and management of cerebral venous sinus thrombosis after a COVID-19 vaccine

Cognitive outcomes in survivors of childhood cancers have been largely understudied

Artificial intelligence helps identify new key-lock pairs against coronavirus

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

Study shows adverse outcomes associated with use of more blood thinners

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