Malignant News and Research

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Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Studying mice has filled encyclopedias with breakthrough medical discoveries. But when it comes to brain cancers, the little rodents have long exhibited fundamental limitations.

30 Nov 2022

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue between the two?

30 Nov 2022

Review: Phenotypes and origins of myeloid-derived suppressor cells

A new review was published in Oncotarget's Volume 13 on November 17, 2022, entitled, "Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more."

30 Nov 2022

New machine learning fusion model for better diagnosis of ovarian lesions

Although ovarian cancer is the deadliest type of cancer for women, only about 20% of cases are found at an early stage, as there are no real screening tests for them and few symptoms to prompt them.

29 Nov 2022

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Although tumors in the nasal cavity and the paranasal sinus are confined to a small space, they encompass a very broad spectrum with many tumor types.

29 Nov 2022

Frequent surveillance imaging not linked to better outcomes following lung cancer surgery

Regular postsurgical screening is critical for patients with lung cancer, the United States' second most prevalent type of cancer and leading cause of cancer deaths.

28 Nov 2022

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

28 Nov 2022

The potential for automatic diagnosis of palpable breast lumps without a radiologist or sonographer

A new study evaluated the efficacy of the volume sweep imaging ultrasound scans and artificial intelligence in providing fully automated and inexpensive breast ultrasound scans and interpretation without the need for experienced radiologists or sonographers.

28 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

The role of bacteria in cancer growth

Tumor-associated microbiota is an important component of the tumor microenvironment (TME) across 33 types of human cancer. However, little evidence is available regarding the spatial distribution and localization of these microbes in tumor cells.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

New approach for delivering medication across the blood-brain barrier to treat brain tumors

Researchers have demonstrated in mice a new approach for delivering medication across the blood-brain barrier to treat tumors that cause aggressive, lethal brain cancer.

20 Nov 2022

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

A new molecular imaging radiotracer can precisely diagnose a variety of cancers, providing a roadmap to identify patients who may benefit from targeted radionuclide therapies.

20 Nov 2022

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

A recent study demonstrated a novel method for delivering anti-cancer drugs, conjugated to modified cell-penetrating peptides across the blood-brain barrier, in mice to treat glioblastoma.

18 Nov 2022

Unique peptides with anti-cancer potential discovered

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.

14 Nov 2022

Updated EULAR recommendations on the use of DMARDs for people with RA

Since their first publication in 2010, the EULAR recommendations for the use of disease-modifying anti-rheumatic treatments (DMARDs) in people with RA have become a most important publication in the field, and their updates are relied upon by many healthcare professionals, professional organizations and other stakeholders to offer an up-to-date and robust analysis on an optimal approach to the application of available treatment options in clinical practice.

11 Nov 2022

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

A multidisciplinary team of Weill Cornell Medicine researchers have received a five-year $5.7 million grant from the National Cancer Institute at the National Institutes of Health to fund a center aimed at developing messenger RNA (mRNA) vaccines to deter cancer development in at-risk groups.

11 Nov 2022

Study identifies a subset of melanoma patients with very low risk of death

Although melanoma is the most serious type of skin cancer, most patients have high chances of surviving the disease.

7 Nov 2022

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

A new treatment developed at Tel Aviv University may significantly enhance the efficacy of chemotherapy in breast cancer patients, reducing the risk for lung metastasis following chemo from 52% to only 6%.

7 Nov 2022

Researchers identify gene expression correlated with response to chemotherapy in medulloblastomas

An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with response to chemotherapy in medulloblastomas, a highly malignant brain tumor affecting pediatric, adolescent, and young adult populations.

7 Nov 2022

Malignant News and Research

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

Review: Phenotypes and origins of myeloid-derived suppressor cells

New machine learning fusion model for better diagnosis of ovarian lesions

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Frequent surveillance imaging not linked to better outcomes following lung cancer surgery

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

The potential for automatic diagnosis of palpable breast lumps without a radiologist or sonographer

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

The role of bacteria in cancer growth

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

New approach for delivering medication across the blood-brain barrier to treat brain tumors

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

Unique peptides with anti-cancer potential discovered

Updated EULAR recommendations on the use of DMARDs for people with RA

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

Study identifies a subset of melanoma patients with very low risk of death

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

Researchers identify gene expression correlated with response to chemotherapy in medulloblastomas

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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