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Gene chips provide new technique to evaluate organ rejection in kidney transplants

A new article appearing in American Journal of Transplantation describes a revolutionary technique for more clearly identifying the possibility of organ rejection in kidney transplants.

19 Nov 2007

Kisspeptin and GPR54 may be the future of ovarian cancer treatment

Kisspeptin and its receptor GPR54 predict a favourable clinical outcome in women with ovarian carcinoma, and are specific for the clear cell carcinoma subtype, research published this week in the online open access journal, BMC Medicine, reveals.

16 Nov 2007

Why are males in evolutionary overdrive even though they have essentially the same genes as females?

The observation that males evolve more quickly than females has been around since 19th century biologist Charles Darwin noted the majesty of a peacock's tail feather in comparison with the plainness of the peahen's.

15 Nov 2007

GPRC5A gene found to be a tumor-suppressor for lung cancer

The GPRC5A gene, which is under-expressed in human lung cancer cells, suppresses lung tumors in mouse models and could provide a key to attacking lung cancer in humans, researchers at The University of Texas M. D. Anderson Cancer Center report in the Nov. 21 edition of The Journal of the National Cancer Institute.

14 Nov 2007

Tumor-suppressor gene for lung cancer identified

14 Nov 2007

Large dose dexamethasone plays important roles in severe acute pancreatitis

Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 - 30% mortality, mainly due to multiple organ failure at its early stage.

5 Nov 2007

Discovery of novel mechanism to predict survival in older women with early stage lung cancer

A novel mechanism to predict survival in older women with early stage lung cancer has been uncoverecd by researchers at UCLA's Jonsson Comprehensive Cancer Center, a discovery that may have significant implications for new treatment approaches.

2 Nov 2007

Blood gene expression signatures predict exposure levels

In a new study, researchers found they could detect toxic levels of acetaminophen in laboratory animals by analyzing gene expression in the blood.

1 Nov 2007

Many medical disorders may be languishing in mountains of discarded gene data

Previously hidden obesity-related genes have been uncovered from old experiments by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

24 Oct 2007

New genetic and phenotypic data involved in autism released to researchers worldwide

The Autism Consortium, a group of researchers, clinicians and families dedicated to radically accelerating research and enhancing clinical care for autism, announced today that it has completed the first genome scan for Autism Spectrum Disorders (ASD) through its Autism Gene Discovery Project and has released the reference data set to a database that autism researchers around the world can use.

22 Oct 2007

Baicalin shows promise for severe acute pancreatitis

¡°Qingyitang¡±, a representative prescription of Traditional Chinese Medicine for SAP was widely used in the orients countries.

18 Oct 2007

Discovery of new antibody that helps detect type 1 diabetes

Researchers at the Barbara Davis Center for Childhood Diabetes and University of Colorado at Denver and Health Sciences Center's School of Medicine have discovered a fourth antibody in human blood which will help more accurately predict who is predisposed to type 1 diabetes.

17 Oct 2007

Direct selection of human genomic loci by microarray hybridization

Researchers at Baylor College of Medicine and Roche NimbleGen Inc., a fully integrated part of Roche Applied Science, have published details of a highly efficient and cost-effective method for capturing targeted regions of the genome via NimbleChip microarrays in preparation for high-throughput 454 Sequencing.

16 Oct 2007

Microarray-based genomic selection accelerates discovery of subtle DNA variations

A new technology developed by scientists at Emory University will allow researchers to more easily discover subtle and overlooked genetic variations that may have serious consequences for health and disease.

15 Oct 2007

Fungus genome yielding answers to protect grains, people and animals

Why a pathogen is a pathogen may be answered as scientists study the recently mapped genetic makeup of a fungus that spawns the worst cereal grains disease known and also can produce toxins potentially fatal to people and livestock.

8 Oct 2007

Gene-chip studies provide new leads in treating abnormal lung development in premature newborns

Some 20 to 40 percent of extremely premature infants suffer abnormal lung development leading to bronchopulmonary dysplasia, a chronic lung disease that can cause long-term breathing problems.

4 Oct 2007

Missouri-Columbia researchers look at mechanisms of cisplatin drug sensitivity

Resistance to chemotherapy treatments can be the worst news a cancer patient ever receives. A pair of researchers at the University of Missouri-Columbia is working steadfastly to learn why some tumors eventually build a tolerance to the common chemotherapy drug cisplatin, in hopes of identifying the particular genes that can be manipulated to make treatment as effective as possible.

3 Oct 2007

Space flight makes bacteria more infectious

Space flight has been shown to have a profound impact on human physiology as the body adapts to zero gravity environments.

25 Sep 2007

DNA microarray chips improved therapy in some patients with incurable cancer

Like many oncologists, Eric P. Lester, M.D., was faced with a dilemma: seven patients with advanced, incurable cancer, an arsenal of drugs that may or may not help them, and not enough solid proof about treatment efficacy to guide him.

20 Sep 2007

New Rensselaer tools speed stem cell research

Engineers at Rensselaer Polytechnic Institute have developed tools to help solve two of the main problems slowing the progress of stem cell research - how to quickly test stem cell response to different drugs or genes, and how to create a large supply of healthy, viable stem cells to study from only a few available cells.

13 Sep 2007