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Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Claudio Franceschi, a world-renowned scientist, professor at the University of Bologna (Italy) and head of the Research Laboratory for Systems Medicine of Healthy Aging at Lobachevsky University, together with other members of an international research team, has described the mechanisms underlying chronic inflammation and identified several risk factors leading to disease.

29 Jan 2020

Study tracks milestones in the history of human disease genetics

Genetic discoveries over the past 25 years have substantially advanced understanding of both rare and common diseases, furthering the development of treatment and prevention for ailments ranging from inflammatory bowel diseases to diabetes, according to a study published in Nature Research in January.

27 Jan 2020

Iron overload, variant gene and malaria resistance linked in African study

A new study shows that a rare genetic mutation giving rise to a variant of the TP53 gene called P47S causes several linked biological processes.

24 Jan 2020

How fast can a new internet standard for sharing patient data catch fire?

Medical professionals have been storing personal health information in electronic form for more than a decade, but it is cumbersome for patients to gather disparate computer and paper records scattered across doctors' offices, hospitals and medical labs.

22 Jan 2020

New technology systematically identifies drug targets in living animals

Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases.

21 Jan 2020

Study shows superior functionality of Duodenum Intestine-Chip populated with organoids

Emulate, Inc. announced today a published study in collaboration with Johns Hopkins University School of Medicine, that demonstrated superior functionality of the Duodenum Intestine-Chip populated with organoids, compared to organoids alone.

14 Jan 2020

The circadian clock is key to reducing radiation‐induced cardiotoxicity

Treatment for breast cancer commonly includes radiation therapy, which offers good chances of success but comes with a serious long-term side effect: toxicity due to radiation that reaches the heart, causing DNA damage in healthy heart cells. Over time, this can lead to heart disease and eventually heart failure.

13 Jan 2020

Study of glycobiology and glycan diagnostics in personalized medicine featured in OMICS special issue

An in-depth look at the science of glycobiology and glycan diagnostics, and their promise in personalized medicine in the current post-genomic era are featured in a special issue of OMICS: A Journal of Integrative Biology, the peer-reviewed interdisciplinary journal published by Mary Ann Liebert, Inc., publishers.

13 Jan 2020

New mathematical model can efficiently model the expression of enzymes in living cells

All living things are made of carbon, and sugars, e.g. glucose, are a very common source of it. Consequently, most cells are good at eating sugars, using enzymes to digest them through a series of chemical reactions that transform the initial sugar into a variety of cell components, including amino acids, DNA building blocks, and fats.

13 Jan 2020

New research demonstrates the importance of personalized brain models

New research conducted by Professors Christophe Bernard and Viktor Jirsa of Aix Marseille Univ, Inserm, Institut de Neurosciences des Systèmes, Marseille, France and Professor Itamar Kahn, director of the Brain Systems Organization in Health and Disease Lab in the Technion's Rappaport Faculty of Medicine, demonstrates the importance of personalized brain models.

12 Jan 2020

New method uses MRI, machine learning to forecast genetic mutations in glioma tumors

Researchers at Osaka University have developed a computer method that uses magnetic resonance imaging (MRI) and machine learning to rapidly forecast genetic mutations in glioma tumors, which occur in the brain or spine. The work may help glioma patients to receive more suitable treatment faster, giving better outcomes.

9 Jan 2020

DNA tests to provide rapid diagnosis of rare diseases in critically ill infants

NHS England is will now provide new DNA testing that can rapidly diagnose rare diseases in critically ill babies and children.

3 Jan 2020

Study uncovers novel targetable axis in mesothelioma patients

A collaborative study of researchers from Thomas Jefferson University, Sbarro Institute for Cancer Research and Molecular Medicine of Temple University, University of Siena, and from the Spanish Center for the Applied Medical Research of the University of Navarra have discovered a novel targetable axis in mesothelioma patients.

26 Dec 2019

Researchers develop powerful computer algorithm for large-scale genomic analysis

Haplotypes are a set of genetic variations that, located side by side on the same chromosome, are transmitted in a single group to the next generation. Their examination makes it possible to understand the heritability of certain complex traits, such as the risk of developing a disease.

20 Dec 2019

AI identifies previously unknown features relevant to cancer prognosis

Artificial intelligence technology developed by the RIKEN Center for Advanced Intelligence Project in Japan has successfully found features in pathology images from human cancer patients, without annotation, that could be understood by human doctors.

18 Dec 2019

Zebrafish 'avatars' help distinguish radiosensitive from radioresistant tumors

Radiotherapy can effectively reduce or even eliminate some tumors; others, however, show enduring resistance. Considering the potentially harmful side effects of radiotherapy, clinicians agree that it is paramount to be able to determine if a patient will benefit from radiotherapy before exposing them to any of the associated risks.

17 Dec 2019