Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

COVID-19 can cause long-term lung damage to children and teens

In a recent study published in the Radiology journal, researchers in Germany assessed the pulmonary dysfunction observed after pediatric coronavirus disease 2019 (COVID-19).

27 Sep 2022

What is the association between body fat and COVID-19?

Researchers recently assessed the association between adipose tissues and COVID-19 by evaluating autopsy cases and profiling adipose tissue responses to SARS-CoV-2 infections.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

Study compares monkeypox PCR testing protocols and efficiency at two U.S. reference labs

In a recent study posted to the medRxiv* preprint server, researchers examined sample collection practices, epidemiological characteristics, and cycle threshold (Ct) values for polymerase chain reaction (PCR) tests used in two reference laboratories in the United States (U.S.) to detect monkeypox virus (MPXV).

25 Sep 2022

How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

Does BA.2 breakthrough infection shift cross-neutralization activity towards the BA.4 and BA.5 Omicron sublineages?

Researchers investigated the SARS-CoV-2 VOC Omicron's immune escape mechanisms.

22 Sep 2022

Can a commercial breath analysis test detect SARS-CoV-2?

Researchers demonstrated the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by a commercial breath analysis test (BAT).

22 Sep 2022

How feasible and accurate are self-collected samples for the diagnosis of monkeypox?

Researchers evaluated the performance of monkeypox virus (MPXV)-infected patients' self-collected versus physician-collected clinical samples, including skin lesions, pharyngeal, and rectal swabs in the diagnostic tests.

22 Sep 2022

How frequent was SARS-CoV-2 and malaria co-infection during the first wave of the pandemic?

Researchers determined the prevalence of circulating SARS-CoV-2 variants and the frequency of co-occurrence of COVID-19 and malaria in Burkina Faso, West Africa.

22 Sep 2022

Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

Population-wide cohort study detects increase in major arterial and venous thrombotic events immediately after COVID-19 diagnoses

In a new study, researchers explored the association between coronavirus disease 2019 (COVID-19) and vascular thrombotic events using a population-wide cohort study across England and Wales.

21 Sep 2022

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

In a new study, researchers assessed the efficacy of the scFv76 antibody against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung damage.

21 Sep 2022

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Researchers evaluated the association between guild-level microbiome signature and the severity and prognosis of SARS-CoV-2 infections by a genome-level metagenomic analysis.

21 Sep 2022

Vaccination drives superior functional antibody breadth compared to natural infection with SARS-CoV-2

Researchers assessed the potency and breadth of antibody recognition and effector function among healthy and high-risk individuals following natural SARS-CoV-2 infection or mRNA COVID-19 vaccination.

21 Sep 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients.

21 Sep 2022

Evidence A.2 lineage of monkeypox is mutating

In a recent study posted to the bioRxiv* preprint server, a team of researchers from India analyzed the whole genome sequences of the monkeypox virus isolated from monkeypox patients with and without international travel histories to understand the phylogenetic relations and genomic evolution of the virus that could contribute to higher transmission rates.

21 Sep 2022

Clinical and epidemiologic features of SARS-CoV-2 in companion animals

In a recent study posted to the Research Square* preprint server, researchers explored the clinical and epidemiologic characteristics of coronavirus disease 2019 (COVID-19) in dogs and cats.

21 Sep 2022

Viable monkeypox virus found in nearly all environmental samples from patient's room in first week of infection

In a new study, researchers investigated the presence of viable monkeypox virus (MPXV) in a room occupied by an infected male patient admitted to the National Centre for Infectious Diseases (NCID), Singapore.

20 Sep 2022

Polymerase Chain Reaction News and Research

Further Reading

COVID-19 can cause long-term lung damage to children and teens

What is the association between body fat and COVID-19?

Common germline variants of APOE contribute to differential COVID-19 outcomes

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

Study compares monkeypox PCR testing protocols and efficiency at two U.S. reference labs

How smallpox and monkeypox viruses affect the nervous system

Does BA.2 breakthrough infection shift cross-neutralization activity towards the BA.4 and BA.5 Omicron sublineages?

Can a commercial breath analysis test detect SARS-CoV-2?

How feasible and accurate are self-collected samples for the diagnosis of monkeypox?

How frequent was SARS-CoV-2 and malaria co-infection during the first wave of the pandemic?

Virology of the human monkeypox virus

Population-wide cohort study detects increase in major arterial and venous thrombotic events immediately after COVID-19 diagnoses

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Vaccination drives superior functional antibody breadth compared to natural infection with SARS-CoV-2

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Why fatigue from long COVID goes beyond simply feeling tired

Evidence A.2 lineage of monkeypox is mutating

Clinical and epidemiologic features of SARS-CoV-2 in companion animals

Viable monkeypox virus found in nearly all environmental samples from patient's room in first week of infection

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