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Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Results of a cellular therapy clinical trial for traumatic brain injury (TBI) using a patient's own stem cells showed that the therapy appears to dampen the body's neuroinflammatory response to trauma and preserve brain tissue, according to researchers at The University of Texas Health Science Center at Houston.

4 Nov 2016

Immune checkpoint cancer therapies may cause rare cardiac side effects linked to unexpected immune response

Combination therapy utilizing two approved immunotherapy drugs for cancer treatment may cause rare and sometimes fatal cardiac side effects linked to an unexpected immune response.

4 Nov 2016

Researchers engineer new weapon to destroy antibiotic-resistant bacteria

Over the past few decades, many bacteria have become resistant to existing antibiotics, and few new drugs have emerged.

2 Nov 2016

Study of new polymer-free DFS indicates non-inferior in-stent late lumen loss at nine-months

A first-in-human study of a new polymer-free drug-filled stent, which provides controlled drug elution from an internal lumen, indicated non-inferior in-stent late lumen loss at nine-months compared with historical zotarolimus-eluting stent (Resolute) data. In addition, there was no binary restenosis, and a high degree of early stent strut coverage with minimal malapposition.

2 Nov 2016

Transcatheter cerebral embolic protection effectively captures embolic debris and safe in TAVR patients

An international study has found that transcatheter cerebral embolic protection (TCEP) is safe, provides effective capture of embolic debris and does not change neurocognitive function for transcatheter aortic valve replacement (TAVR) patients.

2 Nov 2016

NOBLE study shows superiority of CABG over PCI for treatment of left main coronary artery disease

Coronary artery bypass (CABG) surgery is the standard treatment for revascularization in patients with left main coronary artery (LMCA) disease, but use of percutaneous coronary intervention (PCI) for this indication is increasing.

2 Nov 2016

Fred Hutchinson opens first-of-its-kind clinic to provide new immunotherapies for cancer patients

Fred Hutchinson Cancer Research Center today announced the official opening of a first-of-its-kind clinic dedicated to providing innovative immunotherapies for cancer patients in clinical trials.

2 Nov 2016

PLATINUM DIVERSITY study evaluates clinical outcomes after stent implantation in women, minorities

A dedicated stent study conducted exclusively in women and minority patients evaluated clinical outcomes within the era of contemporary PCI, comparing these results to a parallel cohort of white male patients.

2 Nov 2016

RESPECT study: PFO closure more beneficial than medical management in reducing recurrent stroke

Final results from the RESPECT trial found that percutaneously closing a patent foramen ovale (PFO) using the Amplatzer PFO Occluder was superior to medical management in the prevention of recurrent ischemic stroke in patients who previously had a cryptogenic stroke.

2 Nov 2016

TCT 2016 features first report investigations on novel bioresorbable stents

The 28th annual Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation featured a number of first report investigations on novel stents that could become the next generation of bioresorbable stents in patients.

1 Nov 2016

Second annual conference at UofL focuses on improving access to quality health care for adults with IDD

Thanks to advances in medical science and a highly developed network of specialized pediatric health care services, people with intellectual and developmental disabilities (IDD) are much more likely to live into adulthood than they were several decades ago.

1 Nov 2016

Stents can be as effective as surgery for many patients with left main coronary artery disease

A major international study has found that drug-eluting stents, a less-invasive alternative to bypass surgery, are as effective as surgery for many patients with a blockage in the left main coronary artery.

1 Nov 2016

Researchers develop new, less invasive method to perform TAVR for treating aortic valve stenosis

Researchers at the National Institutes of Health have developed a new, less invasive way to perform transcatheter aortic valve replacement (TAVR), a procedure widely used to treat aortic valve stenosis, a lethal heart condition.

31 Oct 2016

Researchers identify two new potential drug targets for treating atherosclerosis

Researchers at Brigham and Women's Hospital have found two new potential drug targets for treating arterial diseases such as atherosclerosis.

31 Oct 2016

OCT offers safe and better guidance for patients undergoing PCI to treat coronary artery disease

Optical coherence tomography (OCT) provides safe and improved guidance for patients undergoing percutaneous coronary intervention to treat coronary artery disease, according to results from the ILLUMIEN III: OPTIMIZE PCI trial.

31 Oct 2016

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

National Institutes of Health researchers have identified a novel role for a gene known as heat shock protein 60 (Hsp60), finding that it is critical in tissue regeneration and wound healing.

27 Oct 2016

Researchers identify genetic risk factor for binge eating

Researchers have identified a gene (CYFIP2) associated with binge eating. This finding represents one of the first examples of a genome-wide significant genetic factor to be identified for binge eating in model organisms or humans.

26 Oct 2016

Researchers use new gene-editing system to hasten quest to cure HIV+ patients

Researchers at UC San Francisco and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.

26 Oct 2016

Novel C. elegans worm strain could serve as tool for testing interventions against AD

Researchers from Yale-NUS College have partnered with researchers from the National University of Singapore and SingHealth Group to develop a novel Caenorhabditis elegans (C. elegans) worm strain which expresses an amyloid beta protein fragment involved in the development of human Alzheimer's Disease (AD).

25 Oct 2016

MTPConnect to provide $7.4 million funding for 14 national projects in medtech, biotech and pharmaceutical sector

MTPConnect - the Medical Technologies and Pharmaceuticals Industry Growth Centre - today announced it will provide $7.4 million of funding over two years for 14 national projects in the medtech, biotech and pharmaceutical (MTP) sector.

25 Oct 2016

Therapeutics News and Research

Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Immune checkpoint cancer therapies may cause rare cardiac side effects linked to unexpected immune response

Researchers engineer new weapon to destroy antibiotic-resistant bacteria

Study of new polymer-free DFS indicates non-inferior in-stent late lumen loss at nine-months

Transcatheter cerebral embolic protection effectively captures embolic debris and safe in TAVR patients

NOBLE study shows superiority of CABG over PCI for treatment of left main coronary artery disease

Fred Hutchinson opens first-of-its-kind clinic to provide new immunotherapies for cancer patients

PLATINUM DIVERSITY study evaluates clinical outcomes after stent implantation in women, minorities

RESPECT study: PFO closure more beneficial than medical management in reducing recurrent stroke

TCT 2016 features first report investigations on novel bioresorbable stents

Second annual conference at UofL focuses on improving access to quality health care for adults with IDD

Stents can be as effective as surgery for many patients with left main coronary artery disease

Researchers develop new, less invasive method to perform TAVR for treating aortic valve stenosis

Researchers identify two new potential drug targets for treating atherosclerosis

OCT offers safe and better guidance for patients undergoing PCI to treat coronary artery disease

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

Researchers identify genetic risk factor for binge eating

Researchers use new gene-editing system to hasten quest to cure HIV+ patients

Novel C. elegans worm strain could serve as tool for testing interventions against AD

MTPConnect to provide $7.4 million funding for 14 national projects in medtech, biotech and pharmaceutical sector

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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