Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Health effects of passive somking studied in first-of-a-kind clinical study

Until bans on in-flight smoking took effect, beginning in 1988, flight attendants were regularly exposed to secondhand smoke.

1 Feb 2007

New testing approach to predict outcome in patients with bladder cancer

A new testing approach has been shown to be effective in identifying patients at the highest risk of cancer relapse after surgery for bladder cancer, say researchers in the February issue of The Lancet Oncology.

29 Jan 2007

Simple diagnostic test detects genetic signs of lung cancer in sputum

DNA coughed up along with phlegm could point to lung cancer, say researchers at the University of Maryland School of Medicine who are developing an inexpensive and non-invasive gene probe to help diagnose early stage lung cancer in current and former smokers.

18 Jan 2007

Selective marker found to indicate aggressive form of breast cancer

Researchers have linked a structural protein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment.

16 Jan 2007

Simple blood test for NT-proBNP level may help predict cardiovascular events

A blood test for patients with coronary heart disease could help predict their risk for subsequent cardiovascular events or death, according to a study in the January 10 issue of JAMA: The Journal of the American Medical Association.

9 Jan 2007

Several specific genetic alterations associated with development of smoking-related cancers

Preliminary research indicates that several specific genetic alterations are associated with the development of smoking-related head and neck skin cancers, according to a report in the January 10 issue of JAMA: The Journal of the American Medical Association.

9 Jan 2007

Simple blood test for the protein NT-proBNP predicts cardiac events

A simple blood test for the protein NT-proBNP accurately predicts the risk of heart attack, heart failure, stroke, and death in patients with known cardiovascular disease, according to a study led by a researcher at the San Francisco VA Medical Center.

9 Jan 2007

Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA

Researchers from the Swiss Nanoscience Institute in Basel have developed a rapid method to detect the activity of a gene involved in controlling tumor growth.

18 Dec 2006

Successful lung cancer surgery not enough to break nicotine dependence in many smokers

A new study has found that close to half of 154 smokers who had surgery to remove early stage lung cancer picked up a cigarette again within 12 months of their potentially curative operation, and more than one-third were smoking at the one year mark. Sixty percent of patients who started smoking again did so within two months of surgery.

12 Dec 2006

Exercise can reduce a smoker's lung cancer risk, but quitting smoking is still most important

In a study of more than 36,000 women, researchers observed that smokers can reduce their risk of developing lung cancer by being physically active. However, they strongly caution that any relative benefit is dwarfed by the benefits gained from quitting smoking.

12 Dec 2006

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

In attempt to identify biological markers, or biomarkers, that can signal the presence of cancer and help oncologists determine the best course of therapy when cancer is present, teams of investigators are scouring stored tissue samples obtained from thousands of cancer patients.

4 Dec 2006

Low-field magnetic separation of monodisperse Fe3O4 nanocrystals

Whether the goal is to separate different types of cells or molecules, methods that rely on the age-old principle of magnetism are a staple among researchers.

20 Nov 2006

Cancer Research Technology and University of Manchester announce collaboration in oncology with AstraZeneca

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, and The University of Manchester have entered into an agreement with AstraZeneca to establish a clinical pharmacology biomarker research and discovery collaboration.

20 Nov 2006

Cigarette smoking and high HPV concentrations associated with greater risk of cervical cancer

Cigarette smoking and concurrent infection with high levels of the virus associated with cervical cancer can increase cancer risk by as much as 27 times, according to a study published in the November 2006 issue of Cancer Epidemiology, Biomarkers & Prevention.

19 Nov 2006

Gene expression and lung cancer prognosis

While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients.

19 Nov 2006

Testosterone replacement therapy appears to be safe - has little effect on the prostate gland

Preliminary research suggests that testosterone replacement therapy for men with low testosterone levels appears to have little effect on the prostate gland, contrary to some reports that this therapy may be harmful, according to a study in the November 15 issue of JAMA: The Journal of the American Medical Association.

14 Nov 2006

Food can have an impact in preventing cancer

With cancer, researchers don't believe "you are what you eat"; that disease is always a direct result of what is, or what isn't, on your dinner plate.

14 Nov 2006

Cancer Research Technology to present discovery updates at BioEurope 2006

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, today announce that Phil L'Huillier, the Director of Business Management, will present at the BioEurope 2006 Annual International Partnering Conference.

6 Nov 2006

Potential for first diagnostic DNA test to guide antidepressant treatment

Treatment of depression is difficult for both patients and for psychiatrists. While there are numerous drugs available that work, finding the right one -- or right combination -- is, at times, a matter of trial and error.

31 Oct 2006

Nanogen announces new patents for inventions related to diabetes and Alzheimer's disease biomarkers

Nanogen has announced that it has been issued four patents by the U.S. Patent and Trademark Office for inventions related to diabetes and Alzheimer's disease biomarkers.

30 Oct 2006

Biomarker News and Research

Further Reading

Health effects of passive somking studied in first-of-a-kind clinical study

New testing approach to predict outcome in patients with bladder cancer

Simple diagnostic test detects genetic signs of lung cancer in sputum

Selective marker found to indicate aggressive form of breast cancer

Simple blood test for NT-proBNP level may help predict cardiovascular events

Several specific genetic alterations associated with development of smoking-related cancers

Simple blood test for the protein NT-proBNP predicts cardiac events

Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA

Successful lung cancer surgery not enough to break nicotine dependence in many smokers

Exercise can reduce a smoker's lung cancer risk, but quitting smoking is still most important

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

Low-field magnetic separation of monodisperse Fe3O4 nanocrystals

Cancer Research Technology and University of Manchester announce collaboration in oncology with AstraZeneca

Cigarette smoking and high HPV concentrations associated with greater risk of cervical cancer

Gene expression and lung cancer prognosis

Testosterone replacement therapy appears to be safe - has little effect on the prostate gland

Food can have an impact in preventing cancer

Cancer Research Technology to present discovery updates at BioEurope 2006

Potential for first diagnostic DNA test to guide antidepressant treatment

Nanogen announces new patents for inventions related to diabetes and Alzheimer's disease biomarkers

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo