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Study pinpoints new marker that can predict Crohn’s disease subtype

Crohn's disease, a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years.

16 Oct 2018

WRAIR clinical study evaluates safety and immunogenicity of Marburg vaccine

The Walter Reed Army Institute of Research this week administered the first vaccine in a Phase 1 clinical trial to evaluate the safety and immunogenicity of a Marburg vaccine candidate in healthy adult volunteers.

15 Oct 2018

Simple procedure could be efficacious intervention for failed back surgery

Failed back surgery (continued low back and leg pain after surgery) is relatively common. With each reoperation, success, as defined by pain reduction, becomes less likely and most patients do not improve.

15 Oct 2018

First-of-its-kind study to test a personalized vaccine in cancer patient

Tamara Strauss has been living with high-grade, stage IV pancreatic neuroendocrine cancer for more than three years. Current treatments, although effective for her, are highly toxic.

15 Oct 2018

Lab study shows effectiveness of potential therapy for treatment-resistant hypothyroidism

A new "metal-coordinated" drug-delivery technology potentially could be used to supplement the standard therapy for hypothyroidism, which affects nearly 10 million Americans, and many more patients worldwide, according to results of a study published in the journal Thyroid this month.

15 Oct 2018

Studies demonstrate effect of Ketogenic Diet on cognitive health in animals

We've all experienced a "gut feeling" -- when we know deep down inside that something is true. That phenomenon and others (like "butterflies in the stomach") aptly describe what scientists have now demonstrated: that the gut and the brain are more closely connected than we once thought, and in fact the health of one can affect the other.

12 Oct 2018

$New guideline supports hypofractionated radiation therapy for men with prostate cancer$

New guideline supports hypofractionated radiation therapy for men with prostate cancer

Three prominent medical societies today issued a new clinical guideline for physicians treating men with early-stage prostate cancer using external beam radiation therapy (EBRT). Adoption of the guideline could make treatment shorter and more convenient for many patients with prostate cancer, the most common malignancy among American men.

12 Oct 2018

Pitt/UPMC researchers awarded NIH grants for brain computer interface research

A team of University of Pittsburgh and UPMC researchers was recently awarded two grants from the National Institutes of Health (NIH) totaling over $8 million to expand their groundbreaking brain computer interface (BCI) research in collaboration with researchers at the University of Chicago and Carnegie Mellon University.

12 Oct 2018

Two major studies on canine cancers may provide clues on human cancers

Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and solid tumors, may be eligible for enrollment.

12 Oct 2018

Research holds promise for treatment of pediatric brain cancer

New research published in Nature Communications from scientists at Huntsman Cancer Institute at the University of Utah, in collaboration with the Stanford University School of Medicine, shows a specific protein regulates both the initiation of cancer spreading and the self-renewal of cancer cells in medulloblastoma, a type of pediatric brain cancer.

12 Oct 2018

Cornell dots equipped with antibody fragments offer a new cancer weapon

Antibody-based imaging of a particularly aggressive form of breast cancer is undergoing clinical trials worldwide, but the path from trial to application is being hampered by a major obstacle: safety.

12 Oct 2018

Gut microbiota could play greater role in pathogenesis of MS than previously thought

In multiple sclerosis, a defective response of the body’s own immune system leads to brain tissue damage. Gastrointestinal microbiota could play a far greater role in the pathogenesis of the disease than previously assumed, researchers at the University of Zurich have now found.

11 Oct 2018

Phase 2 results on tazemetostat EZH2 inhibitor to be presented at ESMO 2018

Epizyme, Inc., a clinical-stage company developing novel epigenetic therapies, announced today that updated efficacy and safety data from the fully enrolled cohort of epithelioid sarcoma (ES) patients in its ongoing Phase 2 trial of tazemetostat will be presented in a poster discussion session at the European Society for Medical Oncology (ESMO) 2018 Congress to be held October 19-23 in Munich, Germany.

10 Oct 2018

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

New research on autism has found, in a mouse model, that drug treatment at a young age can reverse social impairments. But the same intervention was not effective at an older age.

10 Oct 2018

Pioneering software system hopes to make epilepsy surgery safer and easier

A team of researchers, clinicians and engineers from UCLH, UCL, King's College London and the Epilepsy Society have developed a world-leading software system called EpiNav, which stands for epilepsy navigation, and their work is being featured on tonight's episode of the BBC's Trust Me I'm a Doctor.

10 Oct 2018

Cleveland Clinic awarded $6 million NIH grant to study techniques used for ACL reconstruction

The National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, has awarded Cleveland Clinic $6 million to study techniques used for anterior cruciate ligament reconstruction.

10 Oct 2018

Study examines effect of immediate vs delayed pushing during labor on delivery outcomes

The best time to push during the second stage of labor (when the cervix is completely dilated through delivery) is unknown and it's unclear whether the timing affects rates of natural delivery or possible complications.

10 Oct 2018

New hope for children with aggressive form of cancer

Children with an aggressive form of cancer are being given new hope in a world-first trans-Atlantic clinical trial that will test a new three-part treatment.

10 Oct 2018

Unrecognized childhood infections far greater threat than previously realized

Children around the world are suffering from unnoticed infections that are stunting their growth and mental development, new research from an international coalition of scientists reveals.

10 Oct 2018

Personal Genome Diagnostics’ pan-cancer assay being used in new clinical trial

Personal Genome Diagnostics, Inc., a leader in cancer genomics and pioneer in liquid biopsy, today reported that its non-invasive, pan-cancer plasma assay is being used in an important new clinical trial, Nivolumab, Ipilimumab in Patients With Hyper Mutated Cancers Detected in Blood, led by the Cancer Research Institute and Canadian Cancer Trials Group.

9 Oct 2018