Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Study links inflammation and calcium signaling in heart attack

A new study led by University of Iowa researchers has found an unexpected new link between this inflammation in heart muscle following a heart attack and a previously known enzyme called calcium/calmodulin-dependent protein kinase II or CaM kinase II.

10 Mar 2009

BDNF gene shows promise as target for treating obesity

With obesity reaching epidemic levels, researchers at the Ohio State University Medical Center are studying a potentially long-term treatment that involves injecting a gene directly into one of the critical feeding and weight control centers of the brain.

10 Mar 2009

Breakthrough method produces Parkinson's disease patient-specific stem cells free of harmful reprogramming genes

Whitehead Institute researchers have developed a novel method to remove potential cancer-causing genes during the reprogramming of skin cells from Parkinson's disease patients into an embryonic-stem-cell-like state.

8 Mar 2009

Virus-free embryonic-like stem cells made from skin of Parkinson's disease patients

Researchers reporting in the March 6th issue of the journal Cell , a Cell Press publication, have developed a new way to produce human embryonic-like stem cells that are free of the viruses used to insert the key ingredients.

5 Mar 2009

Discovery of new gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH), MIT, the Broad Institute, King's College London (KCL) and other institutions has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

5 Mar 2009

Genetic mutations suggest link between type 1 diabetes and common viral infection

Scientists from Cambridge University have discovered four rare mutations of a gene associated with type 1 diabetes (T1D) that reduce the risk of developing the disease.

5 Mar 2009

Breakthrough produces Parkinson's patient-specific stem cells free of harmful reprogramming genes

Deploying a method that removes potentially cancer-causing genes, Whitehead Institute researchers have "reprogrammed" human skin cells from Parkinson's disease patients into an embryonic-stem-cell-like state.

5 Mar 2009

Bigger genomes more useful

Biologists analyzing DNA in search of the molecular underpinnings of life have consistently favored species with small genomes, which are cheaper to sequence and lack the repetitive "junk" that clutters bigger genomes.

3 Mar 2009

Broccoli and other cruciferous vegetables may protect against asthma, allergic rhinitis and COPD

Here's another reason to eat your broccoli: UCLA researchers report that a naturally occurring compound found in broccoli and other cruciferous vegetables may help protect against respiratory inflammation that causes conditions like asthma, allergic rhinitis and chronic obstructive pulmonary disease.

2 Mar 2009

New gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King's College London (KCL) has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

26 Feb 2009

Why do teeth form in a single row?

A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published in the journal Science.

26 Feb 2009

New insight into the expression of microRNAs

Two independent, upcoming G&D papers lend new insight into the expression of microRNAs and their targets during vertebrate development.

25 Feb 2009

Scientists identify stem-cell genes that help form plant organs

Plant stem-cells are master cells located at the tip of the stem and are part of a structure called the shoot apical meristem (SAM).

24 Feb 2009

Investigational protein may reverse neurodegenerative diseases

An investigational protein that transformed normal laboratory mice into super-jocks holds great promise in developing new treatments for neurodegenerative diseases like Parkinson's, Alzheimer's and ALS (Lou Gehrig's Disease), say researchers at the University of Virginia Health System.

24 Feb 2009

New technique to determine tumor methylation status

Current research suggests that a new technique to determine tumor methylation status can be used in archived tissue samples.

23 Feb 2009

Calculating protein and gene connections in a Parkinson's model

Researchers have created an algorithm that meshes existing data to produce a clearer step-by-step flow chart of how cells respond to stimuli.

22 Feb 2009

Newly discovered mutation can hold the key to treat a large number of different cancers

Scientists have discovered a mutation responsible for cancer progression, a finding with potential implications for the development of treatment against not one, but a series of cancer types since this mutation can be linked to an abnormality recently discovered to exist in all malignancies.

18 Feb 2009

Researchers show how immune system reacts to a hepatitis B infection

Researchers at the Helmholtz Centre in Braunschweig demonstrate how the immune system reacts to a hepatitis B infection.

17 Feb 2009

Discovery of gene network that gave rise to first tooth

A paper in this week's PLoS Biology reports that a common gene regulatory circuit controls the development of all dentitions, from the first teeth in the throats of jawless fishes that lived half a billion years ago, to the incisors and molars of modern vertebrates, including you and me.

10 Feb 2009

New genomic test can personalize breast cancer treatment

A set of 50 genes can be used to reliably identify the four known types of breast cancer, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

9 Feb 2009