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Researchers identify blood-based biomarkers of Parkinson's disease

Researchers at University of California San Diego School of Medicine and Arizona State University have received funding from The Michael J. Fox Foundation for Parkinson's Research to launch a multi-year, $1.7-million effort to identify blood-based biomarkers of Parkinson's disease, which could improve care and accelerate new treatments for the neurodegenerative disorder, which affects nearly 1 million Americans, with 60,000 new cases diagnosed annually.

5 Feb 2019

Oxford Nanopore launches new cDNA Kits for its sequencing technology

Oxford Nanopore has launched new '109' cDNA Kits for its real-time, scalable sequencing technology. The new kits provide high throughput whilst generating complete sequences of full-length cDNA strands, with a low input option of just 1ng PolyA+ RNA.

4 Feb 2019

Mapping mutations in esophageal cancer could improve treatment options

Mutations that cause oesophageal adenocarcinoma have been mapped in unprecedented detail - unveiling that more than half could be targeted by drugs currently in trials for other cancer types.

4 Feb 2019

Study sheds new light on genetics of diabetes in Japanese population

The genetic and genomic revolutions have led to an abundance of data about the genetic factors that confer a predisposition to type 2 diabetes, alongside environmental and lifestyle-related causes.

4 Feb 2019

Developing a Cervical Cancer Test That’s 100% Predictive

An interview with Professor Attila Lorincz, discussing the development of a new cervical cancer test that is able to predict cervical cancer and pre-cancer in 100% cases.

4 Feb 2019

Newly launched CINECA enables researchers to access clinical research data

Registered researchers will have rapid access to an "unprecedented scale" of clinical research data through the new Common Infrastructure for National Cohorts in Europe, Canada and Africa, launched today.

4 Feb 2019

Genetic testing improves diagnoses of abnormalities in developing babies

Genetic testing improves the diagnoses of abnormalities in developing babies that are picked up during ultrasound scans, scientists report today (31 January) in The Lancet.

1 Feb 2019

Discovery of proteins that control mucin secretion reveals clues to treating colon, airway diseases

Cells produce mucins at a constant rate, and when exposed to an allergen or pathogen, they produce more mucin in a rapid burst. Both the constant and rapid mucin secretion is controlled by calcium.

1 Feb 2019

Study reveals how whipworms cause destruction in the gut

Signaling through interleukin-10 (IL-10) receptors on gut immune cells plays a critical role in protecting the gut lining and microbiota from disruption caused by whipworms, according to a study published January 31 in the open-access journal PLOS Pathogens by María Duque-Correa of the Wellcome Sanger Institute in the UK, and colleagues.

1 Feb 2019

Tumor-fighting protein also promotes cancer growth, shows study

Search for a description of "p53" and it becomes clear that this human protein is widely known for its cancer-fighting benefits, leading to its renown as "the guardian of the genome."

1 Feb 2019

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms.

1 Feb 2019

New link found between psychiatric disorders and events during the prenatal stage

Particular genetic variants in the human genome that are important for the development of the brain early in the life of the fetus are frequently found in psychiatric disorders. This is shown by a study carried out by iPSYCH.

31 Jan 2019

Metagenomic analysis helps understand role of bacterial species in Crohn's disease

Research on gut metagenome of patients with Crohn's disease elucidates how it influences the taxonomic and functional composition of intestinal microbiota.

31 Jan 2019

New approach helps clinicians to decide most effective antibiotic treatment courses

A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic - potentially helping overcome antibiotic resistance.

31 Jan 2019