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Molecular signatures reveal why women are more likely to die from glioblastoma

Scientists have discovered molecular signatures that reveal why women are more likely to develop and die from the brain cancer, glioblastoma.

2 Jan 2019

Researchers compile atlas of genetic influences on osteoporosis

A ground-breaking new study led by researchers from the Lady Davis Institute (LDI) at the Jewish General Hospital (JGH) has succeeded in compiling an atlas of genetic factors associated with estimated bone mineral density (BMD), one of the most clinically relevant factors in diagnosing osteoporosis.

2 Jan 2019

Genetically diverse mouse models improves usability for precision medicine for Alzheimer's

Incorporating genetic diversity into a mouse model of Alzheimer's disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging, part of the National Institutes of Health.

28 Dec 2018

Kidney disease risk gene found in more populations than previously known

In the largest population genomics investigation to date, a team of researchers at the Icahn School of Medicine at Mount Sinai, Stanford University, and the University of Colorado have discovered that kidney disease risk variants of the gene APOL1, previously known to affect African and African American populations, are also found at appreciable frequencies in Caribbean and Latin American populations.

28 Dec 2018

Himalayan marmot genome offers clues to high-altitude adaptation

Himalayan marmots can survive at altitudes up to 5,000 meters in the Himalayan regions of India, Nepal, and Pakistan and on the Qinghai-Tibetan Plateau of China, where many of them face extreme cold, little oxygen, and few other resources.

27 Dec 2018

White colonies on kimchi surface is not formed by molds but by yeasts, finds study

WiKim reported that the white colonies on the surface of kimchi is not formed by molds but by "yeasts" and that genomic data was acquired regarding the hygienic safety of the yeast strains.

27 Dec 2018

New study reveals twist in how intoxication happens

As New Year's Eve approaches, many people will experience the familiar buzz that comes from imbibing a favorite cocktail or glass of wine.

27 Dec 2018

New method of cancer stem cells activation to destroy tumors

This risky method of anti-cancer therapy was suggested by scientists of Far Eastern Federal University (FEFU). Their review of mechanisms for molecular activation of stem cells of gliomas (most widely-spread brain tumors) was approved for publishing in the Frontiers in Cellular Neuroscience journal.

26 Dec 2018

Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

In the largest genetic analysis of polycystic ovary syndrome (PCOS) performed to date, an international consortium, including researchers at the Icahn School of Medicine at Mount Sinai, conducted a whole genome association study to identify common genetic architecture for different diagnostic criteria used to define the syndrome.

24 Dec 2018

Researchers identify hundreds of new genes linked to blindness in lab mice

Hundreds of new genes linked to blindness and other vision disorders have been identified in a screen of mouse strains. Many of these genes are likely important in human vision and the results could help identify new causes of hereditary blindness in patients.

24 Dec 2018

Cell-free DNA can be used to predict biological age, according to a new study

Scientists have found that cell-free DNA (cfDNA) within in the blood can reflect differences in the age and health of individuals.

21 Dec 2018

Change in genome of Caucasians could explain higher rates of esophageal cancer

A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds.

21 Dec 2018

Researchers discover new changes occurring in the brain in early Alzheimer's disease

Researchers at the University of Eastern Finland have discovered new changes occurring in the human brain in the early stages of Alzheimer's disease.

21 Dec 2018

Study lays foundation for addressing unresolved questions in human aging

Doctors have long observed that biological age and chronological age are not always one and the same. A 55-year-old may exhibit many signs of old age and have numerous age-related diseases, whereas an 80-year-old may be healthy and robust.

20 Dec 2018

Fundamentals, applications and methods of machine learning used in epigenetics

Machine learning is the study of algorithms and statistical models that computer systems use to progressively improve their performance on a specific task.

20 Dec 2018

Researchers discover cost-efficient, accurate method to examine effectiveness of cardiomyocytes

A faster, more cost-efficient, and more accurate method of examining the effectiveness of human pluripotent stem-cell-derived cardiac muscle cells has been discovered, according to researchers from Penn State.

20 Dec 2018

Genetically modified houseplant can efficiently detoxify indoor air

Our homes are supposed to be safe havens from the outside world. However, studies have shown that household air is more polluted than either office or school air, exposing children and home workers to higher levels of carcinogens than the general population.

19 Dec 2018

Researchers uncover genes that play a key role in the inactivation of X chromosomes

In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference?

19 Dec 2018

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

Genome News and Research

Molecular signatures reveal why women are more likely to die from glioblastoma

Researchers compile atlas of genetic influences on osteoporosis

Genetically diverse mouse models improves usability for precision medicine for Alzheimer's

Kidney disease risk gene found in more populations than previously known

Himalayan marmot genome offers clues to high-altitude adaptation

White colonies on kimchi surface is not formed by molds but by yeasts, finds study

New study reveals twist in how intoxication happens

New method of cancer stem cells activation to destroy tumors

Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

Researchers identify hundreds of new genes linked to blindness in lab mice

Cell-free DNA can be used to predict biological age, according to a new study

Change in genome of Caucasians could explain higher rates of esophageal cancer

Researchers discover new changes occurring in the brain in early Alzheimer's disease

Study lays foundation for addressing unresolved questions in human aging

Fundamentals, applications and methods of machine learning used in epigenetics

Researchers discover cost-efficient, accurate method to examine effectiveness of cardiomyocytes

Genetically modified houseplant can efficiently detoxify indoor air

Researchers uncover genes that play a key role in the inactivation of X chromosomes

Active ingredient in eye drops shows promise for treating aggressive blood cancer

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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