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Ethosomes may be effective carrier system for transdermal delivery

Ethosomes are ethanolic nanovesicles that possess abundant amount of ethanol in its core which provides fluidity to the lipid bilayers and thus by this effect, improves the delivery of molecules into the deep skin layers.

7 Oct 2016

Researchers discover mass migration of inhibitory neurons into the brain's frontal cortex after birth

Researchers at UC San Francisco have discovered a previously unknown mass migration of inhibitory neurons into the brain's frontal cortex during the first few months after birth, revealing a stage of brain development that had previously gone unrecognized.

6 Oct 2016

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

As demand for the widely used blood thinning drug heparin continues to grow, experts worry of possible shortages of the essential medication.

6 Oct 2016

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata--an autoimmune disease that causes patchy, and less frequently, total hair loss--had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

5 Oct 2016

Researchers identify new way to prevent chemotherapy resistance in lung and breast cancers

Researchers at the University of Bradford have discovered a way to prevent chemotherapy resistance in lung cancer by blocking a protein found in cancer cells.

4 Oct 2016

BUSM scientists discover new strategy to treat colon cancers driven by mutant KRAS genes

Researchers from Boston University School of Medicine have discovered a possible strategy to treat colon cancers that are caused by the mutant KRAS gene, which is responsible for approximately half of all colon cancer cases.

4 Oct 2016

Study finds potential therapeutic target for KRAS-driven cancers

Approximately 20 percent of all human cancers have mutations in a gene called KRAS. KRAS-mutant cancers are among the most difficult to treat, with poor survival and resistance to chemotherapy.

3 Oct 2016

Researchers discover how cells know when to stop producing mRNA

A new scientific study conducted by a team of leading geneticists has characterized how cells know when to stop translating DNA into proteins, a critical step in maintaining healthy protein levels and cell function.

30 Sep 2016

Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease

Researchers at Johns Hopkins report they have identified a protein that enables a toxic natural aggregate to spread from cell to cell in a mammal's brain — and a way to block that protein's action.

29 Sep 2016

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

The Alzheimer's Drug Discovery Foundation announces a $2.1 million grant awarded to R. Scott Turner, MD, PhD, of Georgetown University Medical Center to conduct a phase II clinical trial of low-dose nilotinib (marketed as Tasigna for use as a cancer therapy) in patients with Alzheimer's disease.

29 Sep 2016

Component in red wine and grapes can suppress inflammation linked to airway disease

A component of red wine and grapes can help control inflammation induced by a bacterial pathogen that is linked to upper respiratory tract inflammatory diseases such as asthma, chronic obstructive pulmonary diseases (COPD) and middle ear infection (otitis media), according to a study by researchers at Georgia State University.

28 Sep 2016

Department of Defense funds cardiac cell therapy trial for heart failure patients

Building on the results of a recent Cedars-Sinai Heart Institute study published just six months ago, the Department of Defense has awarded a $10 million grant to fund a cardiac cell therapy trial for patients diagnosed with a common but difficult-to-treat form of heart failure.

28 Sep 2016

Researchers identify process in the brains of mice that may explain repetitive actions in Rett patients

Three-year-old Naomi slaps her forehead a few times, bites her fingers and toddles across the doctor's office in her white and pink pajamas before turning her head into a door with a dull thud.

27 Sep 2016

Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

Researchers for the first time have identified the skin phenotype of pediatric eczema or atopic dermatitis (AD) in infants, opening the door for personalized treatment approaches for young children with eczema.

23 Sep 2016

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

Using high-resolution electron microscopy, Columbia University Medical Center researchers have uncovered new details of the structure and function of an intracellular channel that controls the contraction of skeletal muscle.

22 Sep 2016

JAK inhibitors may be first effective treatment for people with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata—an autoimmune disease that causes patchy, and less frequently, total hair loss—had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

22 Sep 2016

Therapeutics News and Research

Ethosomes may be effective carrier system for transdermal delivery

Researchers discover mass migration of inhibitory neurons into the brain's frontal cortex after birth

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Researchers identify new way to prevent chemotherapy resistance in lung and breast cancers

BUSM scientists discover new strategy to treat colon cancers driven by mutant KRAS genes

Study finds potential therapeutic target for KRAS-driven cancers

Researchers discover how cells know when to stop producing mRNA

Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

Component in red wine and grapes can suppress inflammation linked to airway disease

Department of Defense funds cardiac cell therapy trial for heart failure patients

Researchers identify process in the brains of mice that may explain repetitive actions in Rett patients

Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

JAK inhibitors may be first effective treatment for people with alopecia areata

AXT to exclusively distribute Unchained Labs biologics research tools in Australia, New Zealand

Sarepta Therapeutics wins accelerated approval from FDA for Duchenne muscular dystrophy drug

Research findings may help better understand genetic origins of Familial Mediterranean Fever

New study provides most comprehensive picture to date of head and neck cancer stem cells

Next-generation therapeutics eBook eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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