Clinical Trial News and Research

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Researchers prove that UTIs can be prevented by drinking water

University of Miami researchers have shown that drinking enough water can halve the risk of developing a UTI in pre-menopausal women.

2 Oct 2018

Cancer drug trials focus on progression-free survival and overlook health-related quality of life

A McMaster University-led review and analysis of randomized clinical trials is questioning whether interventions which prolong progression-free survival in cancer patients, improve their health-related quality of life.

1 Oct 2018

Study using DFMO shows positive results for children with high risk neuroblastoma

A paper published September 27 in Scientific Reports shows the positive results of a phase II clinical trial using the oral medication DFMO to prevent relapse in children with High Risk Neuroblastoma.

1 Oct 2018

Bowel Cancer UK and Royal College of Surgeons of Edinburgh launch fundraising appeal to enhance surgical research

Bowel Cancer UK, in partnership with the Royal College of Surgeons of Edinburgh, launch a £430,000 fundraising appeal for surgical bowel cancer research to establish Scotland’s first Colorectal Cancer Surgical Research Chair.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Researchers identify genes that could help predict treatment outcomes for parasitic disease

Researchers at the University of York have identified genes in a parasite that could help clinicians predict drug treatment outcomes for patients with visceral leishmaniasis in Brazil.

1 Oct 2018

International conference features cutting-edge research studies on cancer immunotherapy

The Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, to be held in New York, Sept. 30-Oct. 3, will feature cutting-edge research studies from around the world that endeavor to answer urgent questions in the field of cancer immunotherapy to advance progress more rapidly for patients.

1 Oct 2018

$Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors$

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

FDA approves new drug for treatment of lung disease caused by Mycobacterium avium complex

The U.S. Food and Drug Administration today approved a new drug, Arikayce, for the treatment of lung disease caused by a group of bacteria, Mycobacterium avium complex in a limited population of patients with the disease who do not respond to conventional treatment.

29 Sep 2018

Early Parkinson’s disease patients wait too long before seeking medical attention

The time between diagnosis and the institution of symptomatic treatment is critical in the effort to find a cure for Parkinson's Disease.

29 Sep 2018

Common biomarker of kidney disease may also indicate COPD

A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

28 Sep 2018

New combination therapy shows potential in treating incurable HPV-related cancers

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.

28 Sep 2018

Loyola announces plans to produce CAR-T cells for treating cancer

Loyola University Chicago and Loyola Medicine have announced plans to become the first Chicago center to produce cancer-fighting CAR-T cells to treat leukemia and lymphoma.

28 Sep 2018

Broadly neutralizing antibodies offer a new approach to treating HIV infection

A new generation of broadly neutralizing antibodies provides a novel approach to treating HIV infection.

28 Sep 2018

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved VIZIMPRO [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

28 Sep 2018

Non-small cell lung cancer patients survive longer when treated with durvalumab

Non-small cell lung cancer patients survive longer when their treatment includes durvalumab following platinum-based chemoradiotherapy, according to research led by Moffitt Cancer Center.

27 Sep 2018

UCI researchers receive $3.4 million grant to study new class of cancer killing immunotherapeutics

UCI School of Medicine researchers have been awarded a $3.4 million grant by the National Cancer Institute as part of the Beau Biden Cancer Moonshot initiative.

27 Sep 2018

Clinical Trial News and Research

Researchers prove that UTIs can be prevented by drinking water

Cancer drug trials focus on progression-free survival and overlook health-related quality of life

Study using DFMO shows positive results for children with high risk neuroblastoma

Bowel Cancer UK and Royal College of Surgeons of Edinburgh launch fundraising appeal to enhance surgical research

Why patients with ALL relapse after CAR-T cell therapy

Why patients with ALL relapse after CAR-T cell therapy

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Researchers identify genes that could help predict treatment outcomes for parasitic disease

International conference features cutting-edge research studies on cancer immunotherapy

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

FDA approves new drug for treatment of lung disease caused by Mycobacterium avium complex

Early Parkinson’s disease patients wait too long before seeking medical attention

Common biomarker of kidney disease may also indicate COPD

New combination therapy shows potential in treating incurable HPV-related cancers

Loyola announces plans to produce CAR-T cells for treating cancer

Broadly neutralizing antibodies offer a new approach to treating HIV infection

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Non-small cell lung cancer patients survive longer when treated with durvalumab

UCI researchers receive $3.4 million grant to study new class of cancer killing immunotherapeutics

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