Genetic News and Research

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Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

16 Mar 2023

Highly contagious killer fungus likely to spread and cause epizootics across Africa

Researchers studied the prevalence of the fungus Batrachochytrium dendrobatidis (Bd) in a total of 16,900 historical and recent museum specimens, wild-living individuals, and literature records of amphibians from Africa.

16 Mar 2023

Dementia risk is reduced by a Mediterranean diet

A new study in the journal BMC Medicine aimed to analyze the association between dementia incidence and MedDiet adherence as well as assess the interaction between genetic risk and diet for dementia.

15 Mar 2023

Chemists reveal a whole new role for molecular mirroring

With the aid of some sea slugs, University of Nebraska–Lincoln chemists have discovered that one of the smallest conceivable tweaks to a biomolecule can elicit one of the grandest conceivable consequences: directing the activation of neurons.

15 Mar 2023

Malfunctioning of novel regulatory brain mechanism may be an early contributor of Alzheimer's disease

Researchers from Drexel University have uncovered a novel regulatory mechanism in the brain that is essential for making the right kinds of proteins that promote healthy brain function, and its malfunctioning may be an early contributor of the development of Alzheimer's disease.

15 Mar 2023

Researchers uncover new clue as to how "whole genome doubling" drives cancer

A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils.

15 Mar 2023

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Hypnosis is an effective treatment for pain for many individuals but determining which patients will benefit most can be challenging. Hypnotizability testing requires special training and in-person evaluation rarely available in the clinical setting.

15 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

Higher plasma caffeine levels may reduce adiposity and risk of type 2 diabetes

A high blood caffeine level might curb the amount of body fat a person carries and their risk of type 2 diabetes, suggests research published in the open access journal BMJ Medicine.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

A convergent coexpression approach identifies novel genes associated with autism

The current study analyzes transcriptional convergence across many autism risk genes.

14 Mar 2023

How does the gut microbiome affect muscle strength?

Researchers use fecal microbiome transplantation in mouse models to examine the role of gut microbiota in determining muscle strength.

14 Mar 2023

New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

Scientists find a good treatment target for pulmonary hypertension

The vascular smooth muscle cells that normally give blood vessel walls strength and flexibility proliferate and become destructive in pulmonary hypertension, a typically rapidly progressing condition that makes it hard to get blood inside our lungs and oxygen to our bodies.

14 Mar 2023

Study identifies abnormal biomarkers associated with obesity in early elementary-aged Latino youth

In the United States, low-income, Latino youth are disproportionately affected by obesity with 25.8% of Latino youth aged 2-19 considered to have obesity, which is approximately two times more likely when compared to their non-Latino white counterparts.

14 Mar 2023

Genetic News and Research

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

Highly contagious killer fungus likely to spread and cause epizootics across Africa

Dementia risk is reduced by a Mediterranean diet

Chemists reveal a whole new role for molecular mirroring

Malfunctioning of novel regulatory brain mechanism may be an early contributor of Alzheimer's disease

Researchers uncover new clue as to how "whole genome doubling" drives cancer

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Researchers design a virus-resistant, more useful E. coli bacteria

Higher plasma caffeine levels may reduce adiposity and risk of type 2 diabetes

An emerging target for chronic kidney disease treatment - DNA-PKcs

Embryonic stem cells used to recreate thyroid cancer histotypes

A convergent coexpression approach identifies novel genes associated with autism

How does the gut microbiome affect muscle strength?

New genetic animal model may inform potential therapeutic options for Down syndrome

Scientists find a good treatment target for pulmonary hypertension

Study identifies abnormal biomarkers associated with obesity in early elementary-aged Latino youth

The development of the pediatric oral resistome and its role in dental caries

CN Bio appoints Deepak Singh as Vice President of Sales and Marketing

Study reveals the shared genetic basis for endometriosis and other pain conditions

Summarizing the evidence of respiratory transmission of mpox

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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