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Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Children with ALL living in extreme poverty face two-fold greater risk of relapse

Children with acute lymphoblastic leukemia (ALL) who live in extreme poverty and were undergoing maintenance therapy faced an almost two-fold greater risk of relapse compared with kids who weren't as poor, according to a study published in today's issue of Blood.

18 Apr 2023

Did COVID-19-associated lockdowns increase the rate of memory decline in patients with cognitive impairments?

Researchers investigated whether COVID-19-associated lockdown measures had an impact on the cognitive decline rate.

18 Apr 2023

As pandemic emergencies end, people battling long covid feel ‘swept under the rug’

Lost careers. Broken marriages. Dismissed and disbelieved by family and friends.

18 Apr 2023

Lactobacillus probiotics improve vaginal health in asymptomatic women

This study investigated the effect of administering Lactobacillus probiotics (LBPs) on vaginal dysbiosis in asymptomatic women. The results showed that oral intake of LBPs improved vaginal health in women with high Nugent scores.

17 Apr 2023

Lipid molecules enable uptake of therapies into the brain after a stroke

To get therapies into the brain after a stroke, researchers are increasingly making use of the blood–brain barrier, which allows only certain molecules to pass from the blood into the brain.

17 Apr 2023

Digitized brain-heart atlas opens the door for innovative therapies

A team of UCF College of Medicine researchers has created a digital topographical map of the cardiac sympathetic neural network, the region that controls the body's heart rate and its "fight-or-flight" response.

17 Apr 2023

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Metagenomic sequencing can provide rapid and actionable antimicrobial resistance predictions to treat bloodstream infections much faster than conventional laboratory tests, and has the potential to save lives and better manage the use of antibiotics, according to new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April).

17 Apr 2023

Emotion-focused psychotherapy for bipolar disorder increases amygdala activation

A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, identifies a therapeutic tool focused on emotional awareness that increased activation and connectivity of an emotion-regulating center in the brain.

17 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Pre- and post-surgical immunotherapy-based treatment significantly improved lung cancer outcomes

A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to Phase III trial results presented today by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2023.

17 Apr 2023

Experimental mRNA vaccine plus an immunotherapy reduced the likelihood of melanoma recurrence

The combination of an experimental mRNA vaccine with an immunotherapy reduced the likelihood of melanoma recurring or causing death by 44% when compared to immunotherapy alone, a new clinical trial shows.

17 Apr 2023

Many melanoma patients could avoid the risk for toxicity from combination therapies, study suggests

Data from a national clinical trial shows that a striking 89% of patients with desmoplastic melanoma responded to immunotherapy (pembrolizumab) alone, suggesting that many patients could avoid the risk for toxicity from combination therapies and achieve cancer control with this approach to treatment.

17 Apr 2023

Therapy News and Research

Precise genome editing approach can correct mutation that causes sickle cell disease

Children with ALL living in extreme poverty face two-fold greater risk of relapse

Did COVID-19-associated lockdowns increase the rate of memory decline in patients with cognitive impairments?

As pandemic emergencies end, people battling long covid feel ‘swept under the rug’

Lactobacillus probiotics improve vaginal health in asymptomatic women

Lipid molecules enable uptake of therapies into the brain after a stroke

Digitized brain-heart atlas opens the door for innovative therapies

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Emotion-focused psychotherapy for bipolar disorder increases amygdala activation

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Pre- and post-surgical immunotherapy-based treatment significantly improved lung cancer outcomes

Experimental mRNA vaccine plus an immunotherapy reduced the likelihood of melanoma recurrence

Many melanoma patients could avoid the risk for toxicity from combination therapies, study suggests

People with Down syndrome are living longer, but the health system still treats many as kids

A review of the risk factors associated with cancer evolution

Substituting processed or red meat with plant-based foods may reduce risk of type 2 diabetes

Statin use reduces stroke risks in patients with atrial fibrillation

Researchers develop new approach for studying HBV in the lab

Study uncovers hallmarks to improving pancreatic cancer therapy

VR training shown to be as effective as inpatient training for nursing students

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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