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New bioinformatic framework identifies protein that plays key role in diabetic kidney disease

A new bioinformatic framework developed by researchers at University of California San Diego School of Medicine has identified key proteins significantly altered at the gene-expression level in biopsied tissue from patients with diabetic kidney disease, a result that may reveal new therapeutic targets.

16 Nov 2016

Crowdsourcing new prediction tool for better prognosis of metastatic castration-resistant prostate cancer

Knowing the likely course of cancer can influence treatment decisions. Now a new prediction model published today in Lancet Oncology offers a more accurate prognosis for a patient's metastatic castration-resistant prostate cancer.

16 Nov 2016

Retinitis pigmentosa can be slowed by reprogramming metabolism of photoreceptors, study shows

Columbia University Medical Center researchers have demonstrated that vision loss associated with a form of retinitis pigmentosa (RP) can be slowed dramatically by reprogramming the metabolism of photoreceptors, or light sensors, in the retina.

15 Nov 2016

Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

The length of your telomeres appears to be a window into your heart health and longevity, and scientists are measuring them to see if vitamin D and omega-3 supplements really improve both.

14 Nov 2016

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Molecular clocks in cells throughout the body control many physiologic changes in a 24-hour day/night circadian rhythm -- among them the timing of sleep and wakefulness.

14 Nov 2016

Research shows corticotrophs in the brain can influence avoidance behavior after onset of stress

German Resilience Center presents new findings on the resistance to stress. A person exposed to stress can usually rapidly adapt the own behavior to the specific situation.

14 Nov 2016

Stem-cell-derived gap junction cells could be important therapeutic target for treatment of hereditary deafness

A collaboration, including researchers from Juntendo University, demonstrate differentiation from stem cells into specialised cells thought to be the most important therapeutic target for the treatment of hereditary deafness.

14 Nov 2016

HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

A new study presented this week at The Liver Meeting — held by the American Association for the Study of Liver Diseases — found patients with hepatitis C who take direct-acting antiviral medication are at no higher risk for developing liver cancer than those who do not take the medication.

11 Nov 2016

Study shows how Zika virus infection leads to production of smaller disease-causing RNAs

Researchers, led by scientists at the University of Colorado School of Medicine, have found basic molecular processes used by the Zika virus to "hijack" the cells that it infects and potentially how it makes molecules that are directly linked to disease.

11 Nov 2016

Researchers lay foundation for improved TB treatment by targeting new enzyme

Researchers at Johns Hopkins report they have laid the foundation to develop novel antibiotics that work against incurable, antibiotic-resistant bacteria like tuberculosis by targeting an enzyme essential to the production and integrity of bacterial cell walls.

10 Nov 2016

Elucidating IDP behaviour on crowded membranes

IDPs are proteins that contain stretches of amino-acid sequence that are flexible and do not comprise stable structure in isolation. This is in contrast with a more traditional view of proteins as largely occupying a stable native structure that correlates with functions such as enzyme activity or binding.

10 Nov 2016

Exposure to licorice compound disrupts steroid sex hormone production in ovary

A study of mouse reproductive tissues finds that exposure to isoliquiritigenin, a compound found in licorice, disrupts steroid sex hormone production in the ovary, researchers report.

9 Nov 2016

UPCI scientists reveal how cancer cells hijack DNA repair pathways to stay alive

Research by scientists at the University of Pittsburgh Cancer Institute has revealed how cancer cells hijack DNA repair pathways to prevent telomeres, the endcaps of chromosomes, from shortening, thus allowing the tumor to spread. The findings are published today in the journal Cell Reports.

8 Nov 2016

Mild to moderate rise in blood fats increases risk of developing acute pancreatitis

New research from the University of Copenhagen shows that mild to moderate levels of blood fats equals an increased risk developing acute pancreatitis. It is far more serious than we previously believed it to be, according to the professor behind the study.

8 Nov 2016

Scientists identify new way to block action of genetic mutations found in most cancers

Researchers at the University of Illinois at Chicago have identified a new way to block the action of genetic mutations found in nearly 30 percent of all cancers.

7 Nov 2016

High-altitude dwellers prone to chronic mountain sickness produce huge amounts of red blood cells

To better understand why some people adapt well to life at high altitude while others don't, researchers at University of California San Diego School of Medicine studied red blood cells derived from representatives of both groups living in the Andes Mountains.

7 Nov 2016

Researchers create new culture model of human intestine to study inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk.

2 Nov 2016

Researchers identify possible trigger of chronic inflammation in people with diabetes

Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School of Medicine in St. Louis have identified a possible trigger of chronic inflammation.

2 Nov 2016

UGA researchers find new way to improve cancer-killing power of chemotherapy

University of Georgia researchers have found a way to enhance chemotherapy's cancer-killing powers, bringing science one step closer to a more complete cancer treatment.

2 Nov 2016

Two widely prescribed antibiotics may combat bacteria differently than previously thought

Two widely prescribed antibiotics -- chloramphenicol and linezolid -- may fight bacteria in a different way from what scientists and doctors thought for years, University of Illinois at Chicago researchers have found.

2 Nov 2016

Enzyme News and Research

New bioinformatic framework identifies protein that plays key role in diabetic kidney disease

Crowdsourcing new prediction tool for better prognosis of metastatic castration-resistant prostate cancer

Retinitis pigmentosa can be slowed by reprogramming metabolism of photoreceptors, study shows

Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Research shows corticotrophs in the brain can influence avoidance behavior after onset of stress

Stem-cell-derived gap junction cells could be important therapeutic target for treatment of hereditary deafness

HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

Study shows how Zika virus infection leads to production of smaller disease-causing RNAs

Researchers lay foundation for improved TB treatment by targeting new enzyme

Elucidating IDP behaviour on crowded membranes

Exposure to licorice compound disrupts steroid sex hormone production in ovary

UPCI scientists reveal how cancer cells hijack DNA repair pathways to stay alive

Mild to moderate rise in blood fats increases risk of developing acute pancreatitis

Scientists identify new way to block action of genetic mutations found in most cancers

High-altitude dwellers prone to chronic mountain sickness produce huge amounts of red blood cells

Researchers create new culture model of human intestine to study inflammatory bowel disease

Researchers identify possible trigger of chronic inflammation in people with diabetes

UGA researchers find new way to improve cancer-killing power of chemotherapy

Two widely prescribed antibiotics may combat bacteria differently than previously thought

Understanding the DNA Damage Response in Innate Immunity eBook

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