Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Computation and genomics data drive bacterial research into new golden age

A potent combination of powerful new analysis methods and abundant data from genomics projects is carrying microbiology forward into a new era.

10 Dec 2008

Networks of interactive genes may predict Leukemia's development

Rather than testing for individual marker genes or proteins, researchers at the University of California, San Diego (UC San Diego) and the Moores UCSD Cancer Center have evidence that groups, or networks, of interactive genes may be more reliable in determining the likelihood that a form of leukemia is fast-moving or slow-growing.

8 Dec 2008

Study links cone death in retinitis pigmentosa to metabolic problem

Rods and cones coexist peacefully in healthy retinas. Both types of cells occupy the same layer of tissue and send signals when they detect light, which is the first step in vision.

8 Dec 2008

Breakthrough in understanding the phenomenon of nucleolar dominance

Since the machinery involved in nucleolar dominance is some of the same machinery that can go haywire in diseases such as cancer, Pikaard and his collaborators' research may have important implications for applied medical research.

5 Dec 2008

Model unravels rules that govern how genes are switched on and off

For years, scientists have struggled to decipher the genetic instruction book that details where and when the 20,000 genes in a human cell will be turned on or off.

5 Dec 2008

Genetic ancestry of African-Americans reveals new insights about gene expression

The amount of proteins produced in cells—a fundamental determinant of biological outcomes collectively known as gene expression—varies in African American individuals depending on their proportion of African or European genetic ancestry.

5 Dec 2008

Chromatin packaging helps decipher how cancer develops

To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging.

5 Dec 2008

A new approach improves prioritization of disease-associated SNPs

The more often a gene is differentially expressed, the more likely it is to contain disease-associated DNA variants.

5 Dec 2008

New technique provides closer look at DNA and mRNA

In a study in the advance online edition of Nature Structural and Molecular Biology, researchers from Albert Einstein College of Medicine describe a technique for looking more precisely at a fundamental step of a cell's life - a gene, DNA, being read into a message, mRNA.

3 Dec 2008

Scientists find key to keeping killer T cells in prime shape for fighting infection, cancer

Like tuning a violin to produce strong, elegant notes, researchers at The Wistar Institute have found multiple receptors on the outside of the body's killer immune system cells which they believe can be selectively targeted to keep the cells in superb infection- and disease-fighting condition.

30 Nov 2008

Researchers provide new evidence that aging can be slowed

New evidence may explain why it is that we lose not only our youthful looks, but also our youthful pattern of gene activity with age.

26 Nov 2008

Researchers provide new insight into adaptive ability of cells

The Stowers Institute's Rong Li Lab has published findings that shed light on the ability of cells to adapt to disruptions to their basic division machineries - findings that may help explain how cancer cells elude the body's natural defense mechanisms or chemotherapy treatment.

26 Nov 2008

Researchers identify a potentially universal mechanism of aging

Like our current financial crisis, the aging process might also be a product excessive deregulation.

26 Nov 2008

New understanding of processes that regulate genes

Scientists at Penn State have shed light on some of the processes that regulate genes -- such as the processes that ensure that proteins are produced at the correct time, place, and amount in an organism -- and they also have shed light on the evolution of the DNA regions that regulate genes.

25 Nov 2008

Scientists shed light on how DNA is unwound so that its code can be read

Researchers at The Scripps Research Institute have figured out how a macromolecular machine is able to unwind the long and twisted tangles of DNA within a cell's nucleus so that genetic information can be "read" and used to direct the synthesis of proteins, which have many specific functions in the body.

24 Nov 2008

New model predicts risk of recurrence in early stage colon cancer patients

Researchers in the Duke Institute for Genome Sciences & Policy have developed a model for predicting risk of recurrence in early stage colon cancer patients, and have used the model to also predict sensitivity to chemotherapy and targeted therapy regimens.

24 Nov 2008