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Scientists take another step in understanding bacteria that cause Salmonella epidemic

Scientists at the University of Liverpool have taken another step forward in understanding the bacteria that are causing a devastating Salmonella epidemic currently killing around 400,000 people each year in sub-Saharan Africa.

16 Jan 2019

Study points to potential new biomarker and drug target for amyotrophic lateral sclerosis

Research led by stem cell scientists at Harvard University points to a potential new biomarker and drug target for amyotrophic lateral sclerosis, a neurological disease that is extremely difficult to diagnose and treat.

16 Jan 2019

Study shows how herpes viruses and tumors have learned to manipulate the same ancient RNA

Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors have been found to manipulate, Mount Sinai researchers have shown for the first time.

14 Jan 2019

Differences in geographic origin of genes may affect mitochondrial function

Differences in the geographic origin of genes may affect the function of human mitochondria--energy-generating organelles inside of cells--according to a new study.

14 Jan 2019

Researchers identify multiple new subtypes of most common childhood cancer

Like cartographers completing a map, investigators have identified multiple new subtypes of the most common childhood cancer--research that will likely improve the diagnosis and treatment of high-risk patients.

14 Jan 2019

Molecular hallmarks of tumor hypoxia across 19 cancer types discovered

Unlike healthy tissues, tumors thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despite being a well-known cause of therapy resistance and metastasis, the impact of low oxygen, known as hypoxia, on tumor cells is poorly understood.

14 Jan 2019

Genetic variants linked with risk tolerance and risky behaviors

As part of an international research project, a group of scientists from the University of Zurich found genetic variants associated with risk tolerance and risky behaviors. It is one of the first studies to link genetic variants with behavioral outcomes, which are relevant to social science research.

14 Jan 2019

Conducting ChIP-Seq with Low Cell Numbers

An interview with Dr. Kathyrn Cunningham at SfN 2018, providing advice on carrying out Chromatin Immunoprecipitation Sequencing (ChIP-seq) with low cell numbers.

From Active Motif 14 Jan 2019

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications.

11 Jan 2019

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX.

11 Jan 2019

Study shows an unusual mechanism could have thwart the invasion of human genome by junk DNA

In the January 7th edition of Communications Biology, researchers at InsideOutBio argue that an unusual form of DNA with a reverse twist may have helped thwart the invasion of the human genome by junk DNA.

11 Jan 2019

Staphylococcus aureus: Study describes development of resistance to antibiotic for the first time

The Staphylococcus aureus bacterium is one of the commonest pathogens and can even cause sepsis. The new antibiotic dalbavancin is very effective against many bacterial pathogens.

10 Jan 2019

New biomarker may help better predict outcomes in patients with HPV-related head and neck cancers

By analyzing variations in the level of human papillomavirus (HPV) in head and neck cancers, researchers at The University of Texas MD Anderson Cancer Center have discovered a gene signature associated with treatment response and survival in patients.

10 Jan 2019

Novel biomarker links tumor progression to genome instability

Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat.

10 Jan 2019

Viral replication not necessary to cause lethal disease by food-borne pathogen

The replication of a bacterial virus is not necessary to cause lethal disease in a mouse model of a food-borne pathogen called Enterohemorrhagic Escherichia coli, according to a study published January 10 in the open-access journal PLOS Pathogens by Sowmya Balasubramanian, John Leong and Marcia Osburne of Tufts University School of Medicine, and colleagues.

10 Jan 2019

Genome News and Research

Scientists take another step in understanding bacteria that cause Salmonella epidemic

Study points to potential new biomarker and drug target for amyotrophic lateral sclerosis

Study shows how herpes viruses and tumors have learned to manipulate the same ancient RNA

Differences in geographic origin of genes may affect mitochondrial function

Researchers identify multiple new subtypes of most common childhood cancer

Molecular hallmarks of tumor hypoxia across 19 cancer types discovered

Genetic variants linked with risk tolerance and risky behaviors

Conducting ChIP-Seq with Low Cell Numbers

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

Study shows an unusual mechanism could have thwart the invasion of human genome by junk DNA

Staphylococcus aureus: Study describes development of resistance to antibiotic for the first time

New biomarker may help better predict outcomes in patients with HPV-related head and neck cancers

Novel biomarker links tumor progression to genome instability

Viral replication not necessary to cause lethal disease by food-borne pathogen

NYSCF announce partnership with Ngene to develop new disease treatments

NorthShore and Color partner to deliver the power of genomics in routine primary care

Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy

Genetic variations may influence whether vitamin E decreases or increases cancer risk

Scientists identify evolutionary formula for monogamy

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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