Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Research reveals link between elevated BMI and increased risk of gallstone in women

New research reveals a causal association between elevated body mass index (BMI) and increased risk of gallstone disease. Results published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show women are at greater risk of developing gallstones.

12 Jul 2013

Children born after mothers hormonal fertility treatment have increased risk of mental disorders

Whether a child is conceived naturally or in a Petri dish in an incubator has no bearing at all on the child's mental health. However, researchers have identified a small but increased risk of developing a mental disorder such as autism, ADHD or behavioural problems in children whose mothers only received medical treatment to stimulate ovulation and egg development before insemination.

11 Jul 2013

Study shows rates of brain loss caused by aging and AD are higher for women

The rates of regional brain loss and cognitive decline caused by aging and the early stages of Alzheimer's disease (AD) are higher for women and for people with a key genetic risk factor for AD, say researchers at the University of California, San Diego School of Medicine in a study published online July 4 in the American Journal of Neuroradiology.

10 Jul 2013

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

In the constant cross talk between our brain and our gut, two gut hormones are already known to tell the brain when we have had enough to eat. New research suggests that boosting levels of these hormones simultaneously may be an effective new weapon in the fight against obesity.

10 Jul 2013

Multiple pregnancies conceived after IVF associated with increased breast cancer risk

Women who give birth to multiple babies following IVF treatment are at a higher risk of breast cancer than those giving birth to singletons or who remain childless. Dutch investigators from the Omega study group said the explanation may not be the multiple pregnancy per se but a maternal trait related to a higher implantation potential and to breast cancer itself.

9 Jul 2013

Macrophages play essential role in production of progesterone hormone

New research from the University of Adelaide shows for the first time that immune cells known as macrophages are critical to fertility by creating a healthy hormone environment in the uterus.

9 Jul 2013

Anti-cancer compounds offer hope for treating breast cancer

Melbourne researchers have discovered that anti-cancer compounds currently in clinical trials for some types of leukaemia could offer hope for treating the most common type of breast cancer.

9 Jul 2013

Adverse fetal growth, exposure to maternal smoking correlated with lower measures of sperm quality

Studies over the past 20 years have suggested (though not unequivocally confirmed) that semen quality is in decline, reflected most evidently in falling sperm counts and reduced sperm motility.

8 Jul 2013

Researchers fabricate nanotweezers that could be used to control and regulate enzymes

In new research, Hao Yan and his colleagues at Arizona State University's Biodesign Institute describe a pair of tweezers shrunk down to an astonishingly tiny scale. When the jaws of these tools are in the open position, the distance between the two arms is about 16 nanometers-over 30,000 times smaller than a single grain of sand.

5 Jul 2013

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Scientists found genetic variations that could be used to identify women who are most likely to benefit from a certain type of breast cancer prevention drug—and who should avoid it.

3 Jul 2013

Abiraterone can prolong overall survival and delay severe pain in prostate cancer patients

Abiraterone acetate (abiraterone for short, trade name: Zytiga) has been approved in Germany since December 2012 for men with metastatic prostate cancer that is not responsive to hormone blockade, who only have mild symptoms or so far none at all, and in whom chemotherapy is not yet indicated.

3 Jul 2013

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that the TransATAC clinical validation study for its Prosigna Breast Cancer Prognostic Gene Signature Assay, which is based on the PAM50 gene signature, was published in the Journal of Clinical Oncology.

From NanoString Technologies 2 Jul 2013

RORA: A novel candidate gene for autism regulates large number of other genes

A new study by Valerie Hu, Ph.D., professor of biochemistry and molecular medicine at the George Washington University (GW) School of Medicine and Health Sciences (SMHS), reports that RORA, a novel candidate gene for autism discovered by her group in a 2010 study, regulates a large number of other genes associated with autism.

2 Jul 2013

Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

A protein first shown to function in the liver plays a crucial role in pregnancy in mice and has a key role in the human menstrual cycle, according to researchers at the University of Montreal. Mice that were genetically engineered not to produce the liver receptor homolog-1 (Lrh-1) molecule were unable to create the uterine conditions necessary for establishing and sustaining pregnancy, resulting in the formation of defective placentas.

1 Jul 2013

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

A cardiac hormone signaling receptor abundantly expressed both in inflamed tissues and cancers appears to recruit stem cells that form the blood vessels needed to feed tumor growth, reports a new study by scientists at the University of South Florida Nanomedicine Research Center.

30 Jun 2013

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find. A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta (Αβ) plaques that are associated with Alzheimer's disease, a study by researchers with the UC Davis Alzheimer's Disease Center has found.

28 Jun 2013

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Two UC Irvine research groups have received $2.27 million from the JDRF to develop innovative methods of treating and possibly curing Type 1 diabetes.

27 Jun 2013

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome - a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity - is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep.

26 Jun 2013

$Vitamin D and calcium supplements can prevent fractures$

Vitamin D and calcium supplements can prevent fractures

Should women take calcium and vitamin D supplements after menopause for bone health? Recommendations conflict, and opinions are strong. But now, an analysis from the major Women's Health Initiative (WHI) trial throws weight on the supplement side-at least for women taking hormones after menopause. The analysis was published online today in Menopause, the journal of The North American Menopause Society.

26 Jun 2013

Karo Bio extends research collaboration with Pfizer on RORgamma modulators

Karo Bio AB announced today the extension of its existing research collaboration with Pfizer Inc. on RORgamma modulators to the end of 2014. Pfizer will continue to provide full funding for the research costs.

26 Jun 2013

Hormone News and Research

Further Reading

Research reveals link between elevated BMI and increased risk of gallstone in women

Children born after mothers hormonal fertility treatment have increased risk of mental disorders

Study shows rates of brain loss caused by aging and AD are higher for women

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

Multiple pregnancies conceived after IVF associated with increased breast cancer risk

Macrophages play essential role in production of progesterone hormone

Anti-cancer compounds offer hope for treating breast cancer

Adverse fetal growth, exposure to maternal smoking correlated with lower measures of sperm quality

Researchers fabricate nanotweezers that could be used to control and regulate enzymes

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Abiraterone can prolong overall survival and delay severe pain in prostate cancer patients

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

RORA: A novel candidate gene for autism regulates large number of other genes

Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Vitamin D and calcium supplements can prevent fractures

Karo Bio extends research collaboration with Pfizer on RORgamma modulators

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