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Scientists use human stem cells to make pain-killing neurons

Researchers at the University of Sydney have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment.

23 Jan 2020

Researchers identify novel cellular entry factor for AAV vector types

Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types--the most commonly used viral vectors for in vivo gene therapy. AAVs are vectors-or vehicles--that are created from a virus that is made harmless by molecular engineering, and have shown promise transporting genetic therapy treatments to affected tissues.

23 Jan 2020

Researchers grow venom-producing snake organoids in the lab

Researchers from the group of Hans Clevers at the Hubrecht Institute, in an international collaboration, have developed a method to grow snake venom gland cells as organoids.

23 Jan 2020

People who care for a family member or friend with disability put their health in jeopardy

People who regularly care for or assist a family member or friend with a health problem or disability are more likely to neglect their own health, particularly by not having insurance or putting off necessary health services due to cost, according to a study published by the American Psychological Association.

23 Jan 2020

Transcriptional scanning in the sperm may regulate rate of human evolution

Maturing sperm cells turn on most of their genes, not to follow their genetic instructions like normal, but instead to repair DNA before passing it to the next generation, a new study finds.

23 Jan 2020

A two-drug combo that halts growth of cancer cells discovered

UT Southwestern Simmons Cancer Center researchers have discovered a two-drug combo that halts the growth of cancer cells that carry HER2 mutations.

23 Jan 2020

Treatment for low back pain in older adults does not match guidelines

Many Medicare patients with new episodes of low back pain receive care inconsistent with current guidelines - including high use of opioids and advanced imaging tests, reports a study in the February issue of Medical Care.

23 Jan 2020

Researchers solve long-standing mystery linked to contraction of heart cells

We've all felt the effects of an adrenaline rush. Faced with danger, real or perceived, the heart beats faster, breathing quickens and muscles tighten as the body prepares to fight a threat or flee from it.

23 Jan 2020

Discovery could lead to early identification of children at high risk of future type 2 diabetes

Researchers at the University of Plymouth and Nestlé have revealed new insights into the factors that predispose children to developing type 2 diabetes in adult life.

23 Jan 2020

Reelin can reverse the main pathological processes associated with Alzheimer's, other tauopathies

Promoting the signaling pathway of reelin -an essential extracellular protein for the neuronal migration and synaptic plasticity- could be an effective therapeutical strategy to counterbalance the main cognitive, biochemical and behavioral alterations seen in Alzheimer's and other pathologies associated with Tau protein, as shown in a new study with animal models -published in the journal Progress in Neurobiology.

23 Jan 2020

Combination of two immune defense strategies could afford alternative approach to treating sepsis

The human immune system uses two pre-programmed strategies to tackle infection. One is fever, a resistance mechanism that tries to eliminate a pathogen by raising the body's temperature.

23 Jan 2020

Immune system cells facilitate the invasive capacity of glioblastoma

In a study published in Brain Communications, a new Open Access publication of the well-known journal Brain, the team led by Carlos Barcia, researcher at Institut de Neurociències of the Universitat Autònoma de Barcelona, analyzed the role of immune cells in the expansion of glioblastoma, the most aggressive brain tumor.

23 Jan 2020

Patient multimorbidity increases GPs’ likelihood of burnout

There is a difference between seeing a patient with a catalogue of two or more serious chronic diseases and a healthy patient who just needs a prescription to treat a case of cystitis.

23 Jan 2020

Scientists discover new drug target for prostate cancer in the non-coding genome

Scientists at Princess Margaret Cancer Centre have identified the drivers of a crucial gene involved in prostate cancer, revealing new targets for drug design.

23 Jan 2020

Scientists call for more effort to map the human exposome

An international team of researchers is calling for a large-scale effort to map the health effects of cumulative exposure to environmental components such as chemical pollutants.

23 Jan 2020

Research reveals damaging impact of visible and infrared light on the skin

The damage visible and infrared light can do to our skin has been revealed for the first time in new research by scientists at Newcastle University, UK.

23 Jan 2020

Study casts doubt on the reliability of donated kidney assessment for transplant

A study led by researchers at Columbia University Irving Medical Center have made an important discovery about the way donated kidneys are assessed before transplantation, that could call into question current decision-making processes about whether an organ can be used or not.

23 Jan 2020

Research News and Research

Scientists use human stem cells to make pain-killing neurons

Researchers identify novel cellular entry factor for AAV vector types

Researchers grow venom-producing snake organoids in the lab

People who care for a family member or friend with disability put their health in jeopardy

Transcriptional scanning in the sperm may regulate rate of human evolution

A two-drug combo that halts growth of cancer cells discovered

Treatment for low back pain in older adults does not match guidelines

Researchers solve long-standing mystery linked to contraction of heart cells

Discovery could lead to early identification of children at high risk of future type 2 diabetes

Reelin can reverse the main pathological processes associated with Alzheimer's, other tauopathies

Combination of two immune defense strategies could afford alternative approach to treating sepsis

Immune system cells facilitate the invasive capacity of glioblastoma

Patient multimorbidity increases GPs’ likelihood of burnout

Scientists discover new drug target for prostate cancer in the non-coding genome

Scientists call for more effort to map the human exposome

Research reveals damaging impact of visible and infrared light on the skin

Study casts doubt on the reliability of donated kidney assessment for transplant

Study uncovers how common stomach bacterium maintains its corkscrew-like shape

Protein p38 plays key role in supporting lung cancer growth

New Cal Poly study identifies effective weight loss maintenance strategies

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