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Researchers identify protein that degrades and inhibits infectious biofilms

Many infectious pathogens are difficult to treat because they develop into biofilms, layers of metabolically active but slowly growing bacteria embedded in a protective layer of slime, which are inherently more resistant to antibiotics.

9 Dec 2016

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

ABIVAX an innovative biotechnology company targeting the immune system to eliminate viral disease, announced today that the Company presented new preclinical data on ABX464, ABIVAX's first-in-class drug candidate for a functional cure of patients with HIV/AIDS, during this week's HIV DART scientific conference in Los Cabos, Mexico.

9 Dec 2016

Research findings could pave way for synthesis of biologically active oligopeptides

The research community and pharmaceutical industry have had a long-standing interest in developing peptide-based therapeutics owing to their high target specificity, potent activity, and small size relative to protein-based biologics.

9 Dec 2016

Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Psoriasis is well-known for causing too many skin cells on elbows, knees, and across the body, but people living with psoriasis may also be at an increased risk of heart disease.

9 Dec 2016

High levels of copeptin could increase risk of kidney, heart disease in Type 1 diabetes patients

Type 1 diabetes patients with elevated albumin in their urine had three times the risk of life-threatening kidney and cardiac disease as those with normal levels, according to researchers at the University of Colorado Anschutz Medical Campus.

8 Dec 2016

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

A University of North Carolina Lineberger Comprehensive Cancer Center-led analysis has found that women who are 65 years or older with metastatic breast cancer were more likely to have a cancer-linked genetic alterations in their tumors, and had a larger total number of genetic alterations, than younger patients overall.

7 Dec 2016

Disturbances in the body’s carbon monoxide metabolism linked to circadian disruption

Chronobiologists from Charité - Universitätsmedizin Berlin have shown that the body's carbon monoxide metabolism is closely linked to the body's circadian (internal) clock.

7 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

TSRI scientists reveal how vision-loss treatment may leave the eyes, kidneys vulnerable to cellular damage

A common class of drugs for vision loss may actually add to the problem in some patients, according to new research co-led by scientists at The Scripps Research Institute (TSRI).

7 Dec 2016

Scientists uncover changes in immediate environment of DNA after fertilization

A team of scientists at the Helmholtz Zentrum München shows changes in the immediate environment of DNA after the ovum and sperm fuse to form the zygote. The results suggest why all conceivable somatic cells can develop from the germ cells. The study has been published in the journal 'Genes and Development'.

6 Dec 2016

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Imagine a key that opens a pin tumbler lock. A very similar key can also fit into the lock, but upside down in comparison to the first key.

6 Dec 2016

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.

6 Dec 2016

Small fat-burning molecule could help combat global epidemic of obesity

A small molecule could provide valuable help in combating the global epidemic of obesity.

6 Dec 2016

Researchers develop new microfluidic device to study brain inflammation

The blood-brain barrier is a network of specialized cells that surrounds the arteries and veins within the brain. It forms a unique gateway that both provides brain cells with the nutrients they require and protects them from potentially harmful compounds.

6 Dec 2016

Molecule News and Research

Researchers identify protein that degrades and inhibits infectious biofilms

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

Research findings could pave way for synthesis of biologically active oligopeptides

Studies show how overactive immune response may contribute to heart disease in psoriasis patients

High levels of copeptin could increase risk of kidney, heart disease in Type 1 diabetes patients

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

Disturbances in the body’s carbon monoxide metabolism linked to circadian disruption

Enzyme that cleaves beta carotene may control testosterone levels

TSRI scientists reveal how vision-loss treatment may leave the eyes, kidneys vulnerable to cellular damage

Scientists uncover changes in immediate environment of DNA after fertilization

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

Small fat-burning molecule could help combat global epidemic of obesity

Researchers develop new microfluidic device to study brain inflammation

Metabolic pathway that shows potential to slow aging may drive brain cancer

Honey Profiling for Impurities and Falsifications

Experimental T-cell therapy shows promise in preventing AML relapse

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

Sperm tail enzymes inspire nanobiotechnology

Cornell researchers develop chemical probe activated by UV light to control inflammation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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