Compound News and Research

RSS

Baby products linked to raised chemicals levels in babies urine

Researchers in the United States are warning the parents of babies to cut down on their use of talcum powder, shampoo and lotions after a study has linked them to high levels of hormone-altering chemicals in infants urine.

18 Feb 2008

Maslinic acid from olives shows anti-cancer properties

A research group of the University of Granada has found out that maslinic acid, a compound present in the leaf and the olive skin wax extracted from alpeorujo (crushed olive pulp), has the capacity of preventing cancer as well as regulating apoptosis in carcinogenic processes.

14 Feb 2008

One red wine good, two bad!, says study

One drink of either red wine or alcohol slightly benefits the heart and blood vessels, but the positive effects on specific biological markers disappear with two drinks, say researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital.

13 Feb 2008

Toxic blue-green algae may provide new anti-cancer drugs

A collaborative team of researchers spearheaded by Dennis Carson M.D., professor of medicine and director of the Rebecca and John Moores UCSD Cancer Center at the University of California, San Diego (UCSD) has identified a potent new anti-cancer drug isolated from a toxic blue-green algae found in the South Pacific.

12 Feb 2008

Novel drug shows promise in limiting heart attack damage

A novel drug designed to lessen muscle damage from a heart attack has passed initial safety tests at the Duke Clinical Research Institute.

8 Feb 2008

Experimental drug shows promise for cystic fibrosis

An experimental drug that has proven effective in treating muscular dystrophy also works for cystic fibrosis, according to researchers at the University of Alabama at Birmingham (UAB).

5 Feb 2008

Isocitric acid from fermentation of sunflower oil - a new building block for pharma?

The citric acid cycle, one of the most important metabolic processes in our bodies, was formulated in 1937. Since then, all of the intermediates have been produced in multigram quantities - with one exception, (2 R,3S)-isocitric acid.

4 Feb 2008

Wyeth launches generic version of PROTONIX

Wyeth and its business partner, Nycomed, have announced the U.S. launch of Wyeth's own generic version of PROTONIX tablets, in response to the at-risk launch of generic pantoprazole tablets in the U.S. by Teva Pharmaceuticals USA, Inc. on December 21, 2007.

31 Jan 2008

Synthesis of natural molecule could lead to better anti-cancer drugs

In early 2007, Northwestern University chemist Karl Scheidt's interest was piqued when marine chemist Amy Wright reported in the Journal of Natural Products that a new natural compound derived from an uncommon deep-sea sponge was extremely effective at inhibiting cancer cell growth.

24 Jan 2008

New method enables design, production of extremely novel drugs

A new chemical synthesis method based on a catalyst worth many times the price of gold and providing a far more efficient and economical method than traditional ones for designing and manufacturing extremely novel pharmaceutical compounds is described by its University at Buffalo developers in a review article in the current issue of Nature.

24 Jan 2008

New compounds for treating tuberculosis and malaria

University of Navarra PhD in chemistry researcher, Esther Vicente, has discovered new compounds active for treating tuberculosis and malaria.

23 Jan 2008

An emerging candidate for protecting patients from liver injury after abdomen surgery

Many patients worldwide are going to receive major abdomen surgery or intestine transplantation every year and expect to be afflicted with liver injury afterwards.

17 Jan 2008

Supplements of lipoic acid could reduce atherosclerosis, weight gain

A new study done with mice has discovered that supplements of lipoic acid can inhibit formation of arterial lesions, lower triglycerides, and reduce blood vessel inflammation and weight gain - all key issues for addressing cardiovascular disease.

15 Jan 2008

FDA extends review of Genasense NDA appeal in chronic lymphocytic leukemia

Genta Incorporated has announced that the Food and Drug Administration (FDA) has extended its review of Genta's appeal of the non- approvable decision for a New Drug Application (NDA) that proposed the use of Genasense (oblimersen sodium injection) plus chemotherapy in patients with relapsed or refractory chronic lymphocytic leukemia.

15 Jan 2008

Memantine and Alzheimer's

In a study published this month in the Journal of Alzheimer's Disease, researchers from the University of Aberdeen report that the drug memantine, used for the treatment of Alzheimer's disease and praised as "the first and only representative of a new class of Alzheimer drugs" works in fact similar to other existing compounds, and is beneficial only in a narrow concentration range.

14 Jan 2008

Review of Memantine for Alzheimer's

11 Jan 2008

Bio-identical hormone replacement therapies targeted by FDA

The U.S. Food and Drug Administration (FDA) sent letters warning seven pharmacy operations that the claims they make about the safety and effectiveness of their so-called "bio-identical hormone replacement therapy," or "BHRT" products are unsupported by medical evidence, and are considered false and misleading by the agency.

10 Jan 2008

Soybeans for hot flashes

Researchers at Beth Israel Deaconess Medical Center (BIDMC) have found that a compound in soybeans is effective in reducing the frequency and severity of hot flashes in menopausal women.

10 Jan 2008

Researchers trigger insulin production in diabetic mice

If the human body were a stage, then proteins would rank among the lead actors in the play we call "Life."

9 Jan 2008

NicOx extends ophthalmology agreement with Pfizer

NicOx S.A. has announced it has signed an extension of its March 2006 collaboration agreement, which grants Pfizer Inc the exclusive right to apply its proprietary nitric oxide-donating technology to drug discovery research in the field of ophthalmology.

9 Jan 2008