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Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Frontotemporal dementias are a group of fatal and debilitating brain disorders for which there are no cures.

26 Jul 2021

Newly identified ultra-rare inherited genetic variants may confer significant autism risk

Researchers have identified a rare class of genetic differences transmitted from parents without autism to their affected children with autism and determined that they are most prominent in "multiplex" families with more than one family member on the spectrum.

26 Jul 2021

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

St. Jude Children's Research Hospital investigators have demonstrated that comprehensive genomic sequencing of all pediatric cancer patients is feasible and essential to capitalize on the lifesaving potential of precision medicine.

26 Jul 2021

Nasal swabs reveal muted antiviral response in patients who developed severe COVID-19

Over the past 18 months, researchers have learned much about COVID-19 and its viral cause, SARS-CoV-2. They know how the virus enters the body, coming in through the nose and mouth and beginning its infection in the mucus layers of the nasal passageway.

26 Jul 2021

Variations in human ACE2 genetics associated with coronavirus susceptibility

In a recent study, the researchers sought to understand the genetic variability in ACE2 that may contribute to inconsistent clinical outcomes of COVID-19.

25 Jul 2021

Novel therapeutic agent could be effective for treating cancers with certain gene mutations

Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal of the American Association for Cancer Research, in July.

23 Jul 2021

Study brings scientists one step closer to solving the mystery of aging

The human body is essentially made up of trillions of living cells. It ages as its cells age, which happens when those cells eventually stop replicating and dividing.

23 Jul 2021

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

The body's first encounter with SARS-CoV-2, the virus behind COVID-19, happens in the nose and throat, or nasopharynx. A new study in the journal Cell suggests that the first responses in this battleground help determine who will develop severe disease and who will get through with mild or no illness.

23 Jul 2021

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

A new study has been published on the bioRxiv* preprint server, which has used MS to identify T cell epitopes of SARS-CoV-2 conserved protein, i.e., the membrane glycol protein (MGP) and the non-structure protein-13 (NSP13).

23 Jul 2021

Clinical trials during a pandemic – lessons from COVID-19

In this interview, Dr. Benedicte Roquebert, Dr. Stephanie Haim-Boukobza and Dr. Souad Mehlal discuss how COVID-19 has resulted in new ways to think about clinical trials during a pandemic.

From Cerba Research 23 Jul 2021

Researchers develop a transferrable and integrative type I CRISPR-based platform to edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Study: Women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing

A new study by Fergus Couch, Ph.D., of Mayo Clinic Cancer Center, along with collaborators from the CARRIERS consortium, suggests that most women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing.

22 Jul 2021

Chemotherapy drugs can induce mutations that lead to relapse in pediatric ALL patients

Chemotherapy has helped make acute lymphoblastic leukemia (ALL) one of the most survivable childhood cancers.

22 Jul 2021

Artificial intelligence tool enriches a gold-mine in cancer genomics

The fragments of cancer DNA analysed by the authors of this new study originate from the human genome, the sequence of which results from millions of years of evolution, and has been shaped by "copy-paste-edit" processes and co-evolution with parasitic elements.

22 Jul 2021

Cell-analysis method could pave the way for new vaccine strategies against tuberculosis

A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world.

22 Jul 2021

Study increases knowledge of the genetics behind aortic aneurysm

A new study increases knowledge of the genetics behind aortic aneurysm, a disease that can spark life-threatening events like aortic dissections and ruptures.

22 Jul 2021

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

A recent study conducted at the University of Texas Science Center, Houston, in the USA, has revealed that upon infection, SARS-CoV-2 alters the host chromatin architecture to suppress antiviral interferon-responsive genes and augment inflammatory genes. The study is currently available on the bioRxiv* preprint server.

22 Jul 2021

Genes News and Research

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Newly identified ultra-rare inherited genetic variants may confer significant autism risk

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

Nasal swabs reveal muted antiviral response in patients who developed severe COVID-19

Variations in human ACE2 genetics associated with coronavirus susceptibility

Novel therapeutic agent could be effective for treating cancers with certain gene mutations

Study brings scientists one step closer to solving the mystery of aging

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

Clinical trials during a pandemic – lessons from COVID-19

Researchers develop a transferrable and integrative type I CRISPR-based platform to edit superbugs

Study: Women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing

Chemotherapy drugs can induce mutations that lead to relapse in pediatric ALL patients

Artificial intelligence tool enriches a gold-mine in cancer genomics

Cell-analysis method could pave the way for new vaccine strategies against tuberculosis

Study increases knowledge of the genetics behind aortic aneurysm

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

Largest genetic study identifies new drug targets to treat type 1 diabetes

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Researchers identify immune protein linked to rare neurodegenerative disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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