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Researchers develop tool that speeds up analysis and publication of biomedical data

Researchers at the Icahn School of Medicine at Mount Sinai have developed a tool that speeds up the analysis and publication of biomedical data from many months or years to mere minutes, transforming the way researchers communicate results of their studies.

15 Nov 2018

Researchers discover key factors behind intestinal inflammation in CVID patients

Oregon State University researchers have discovered two key factors behind the intestinal inflammation that plagues people suffering from a disorder that affects their immune system.

14 Nov 2018

Speed and error rate of DNA synthesis influenced by DNA structure

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy of Sciences showed that sequences with the potential to form unusual DNA conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.

14 Nov 2018

New technology based on moths and magnets could help treat genetic diseases

A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes that give rise to diseases like sickle cell, muscular dystrophy and cystic fibrosis.

14 Nov 2018

Transgenic rat model may provide new insights into cerebral amyloid angiopathy

In a report in The American Journal of Pathology investigators describe the generation of a successful novel transgenic rat model that accumulates amyloid specifically in brain blood vessels and strongly mimics many of the associated detrimental changes that are observed in humans - a condition known as cerebral amyloid angiopathy, which is also commonly observed in Alzheimer disease.

13 Nov 2018

Researchers discover possible path forward in preventing cancers tied to two viruses

Researchers from the University of Minnesota, the Howard Hughes Medical Institute, and the University of Toronto have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis--more commonly known as mono or the "kissing disease"--that infects millions of people around the globe each year.

12 Nov 2018

Failed DNA repair triggers chromosomal chaos in cancer cells

Researchers have established the trigger for catastrophic events that occur within the chromosomes of cancer cells and lead to cancer cell death.

12 Nov 2018

Common bacteria that cause foodborne diseases found to be resistant to antibiotics

Brazil's Ministry of Health received reports of 11,524 outbreaks of foodborne diseases between 2000 and 2015, with 219,909 individuals falling sick and 167 dying from the diseases in question.

9 Nov 2018

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC San Francisco and Washington University School of Medicine in St. Louis.

9 Nov 2018

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

About 1.5 billion years ago, tiny visitors came to live inside the cells that later evolved into all plant and animal life -- including humans.

9 Nov 2018

ChromDesign project trains budding scientists in 3D architecture of genome

How does the three-dimensional architecture of our genes affect the differentiation of cells and development of diseases? This is the question behind the European Innovation Training Network "ChromDesign- Chromatin and Design".

8 Nov 2018

Monash researchers provide insight into intricate peptide changes affecting immune system

Human leukocyte antigen molecules are a group of proteins that help the immune system identify foreign invaders such as viruses and bacteria and which impact a wide variety of clinical outcomes including infection and cancer.

8 Nov 2018

Researchers develop solution to ensure long-term safe storage of sensitive health data

Researchers from the Collaborative Research Center CROSSING at Technische Universität Darmstadt (Germany) have developed a solution that will ensure decades of safe storage for sensitive health data in a joint project with Japanese and Canadian partners.

8 Nov 2018

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

The aim of "precision medicine" is to devise individualized treatment strategies and therapies. Statistical methods play an important role in predicting the efficacy of drugs from clinical study data, based on patient characteristics.

8 Nov 2018

One type of Chlamydia protein manipulates human cells in two different ways

When Chlamydia trachomatis, the bacterium that causes one of the most common sexually transmitted infections worldwide, infects a human cell, it hijacks parts of the host to build protective layers around itself.

8 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Tracking down microRNA candidates linked to disease

What started as Ninad Oak's side project turned out into something much larger, his doctorate thesis. "The project started as my qualifying exam that I proposed at the end of my first year of graduate school," said Oak, a graduate student in molecular and human genetics in Dr. Sharon E. Plon's lab. "This was an off topic qualifying exam at the time, meaning the lab had not worked on this topic before."

7 Nov 2018

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Scientists are making strides in developing liquid biopsies for brain tumors by detecting tumor DNA in the fluid from around the brain and spine.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

Genetics can be used to predict a patient's response to antipsychotic drug treatment for schizophrenia, according to a recent study by investigators at The Feinstein Institute for Medical Research. The findings were published online today in the American Journal of Psychiatry.

5 Nov 2018

Genome News and Research

Researchers develop tool that speeds up analysis and publication of biomedical data

Researchers discover key factors behind intestinal inflammation in CVID patients

Speed and error rate of DNA synthesis influenced by DNA structure

New technology based on moths and magnets could help treat genetic diseases

Transgenic rat model may provide new insights into cerebral amyloid angiopathy

Researchers discover possible path forward in preventing cancers tied to two viruses

Failed DNA repair triggers chromosomal chaos in cancer cells

Common bacteria that cause foodborne diseases found to be resistant to antibiotics

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

ChromDesign project trains budding scientists in 3D architecture of genome

Monash researchers provide insight into intricate peptide changes affecting immune system

Researchers develop solution to ensure long-term safe storage of sensitive health data

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

One type of Chlamydia protein manipulates human cells in two different ways

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Tracking down microRNA candidates linked to disease

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Scientists discover new details about UHRF1 protein

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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