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UVA scientists discover a key determinant of multiple sclerosis risk

University of Virginia School of Medicine scientists have discovered a key determinant of our risk for multiple sclerosis (MS), advancing efforts to prevent and better treat the disease.

7 Jun 2023

The HEART Clinic keeps rehab within the reach for stroke, Parkinson’s patients

The first time Craig Hawkins arrived at the free physical therapy clinic, the aftereffects of his stroke weighed heavy. He rolled up in a wheelchair with a tracheotomy, and had already exhausted his medical benefits.

7 Jun 2023

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

A promising new targeted cancer therapy will soon be available to certain patients with advanced pancreatic cancer – from the comfort of their home.

7 Jun 2023

How do antibiotics affect the ecology of the gut microbiome?

Each person's gut microbiome contains a specific community of microorganisms that normally remains stable for years. However, it can be thrown off balance by factors such as dietary changes, infections or medications. Antibiotics in particular have a strong influence on the microbiome. In response, microorganisms employ various resistance mechanisms, with individual bacterial populations evolving through selection of antibiotic-resistant variants. Yet, the extent and mechanisms of these processes and their impact on the ecology of the microbial community are poorly understood.

7 Jun 2023

Elucidating developmentally sensitive mechanisms of cognitive behavioral therapy

The Brain & Behavior Research Foundation (BBRF) is hosting a free webinar, "Developing New Treatments for Childhood Anxiety and OCD: Can Cognitive Control Help Kids Grow Out of Illness?" on Tuesday, June 13, 2023, at 2:00 pm EST. The presenter will be Kate D. Fitzgerald, M.D., Ruane Professor of Child and Adolescent Psychiatry at Columbia University/New York State Psychiatric Institute.

7 Jun 2023

New strategy to grow and measure how tumor organoids respond to therapy

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers.

7 Jun 2023

Oral semaglutide outperforms other medications in type 2 diabetes treatment, significantly reducing HbA1c and body weight

Orally administered semaglutide shows significant efficacy in reducing HbA1c and body weight in patients with type 2 diabetes compared to other treatments. The study includes a large number of participants from multiple trials.

7 Jun 2023

New insight from patients on what helps or hinders medication-assisted opioid use disorder treatment

Patients would be more willing to enter medication-assisted treatment for opioid use disorder if existing stigmas were reduced and more accessible payment support was readily available, a West Virginia University study finds.

6 Jun 2023

Low-carb breakfast tames glucose spikes in type 2 diabetes

Low-carbohydrate diet reduces postprandial glucose and glycemic variability in type 2 diabetics as compared to those fed a standard low-fat breakfast.

6 Jun 2023

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

Depression is a leading cause of disability around the world and contributes greatly to the global burden of disease.

6 Jun 2023

New folate-targeting magnetic microrobot system shows great potential in cancer treatment

The limited ability of microrobots to assist drugs in entering cells hinders their therapeutic efficacy. To address this, the cancer-targeting molecule folic acid (FA) was introduced to microrobots to promote drug uptake by cancer cells via receptor-ligand-mediated endocytosis.

6 Jun 2023

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

Currently there are no contraceptives capable of producing permanent sterilization in companion animals. Spaying, the surgical removal of the ovaries and uterus, is the most widely used strategy to control unwanted reproduction in female cats.

6 Jun 2023

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

Therapeutic nanocarriers engineered from adult skin cells can curb inflammation and tissue injury in damaged mouse lungs, new research shows, hinting at the promise of a treatment for lungs severely injured by infection or trauma.

6 Jun 2023

Two studies seek to understand the drivers of chronic and progressive phase of COVID-19

Early studies of COVID-19 focused on the acute phase of the disease. However, attention has now turned to the long-term consequences of the disease, which are also significant causes of morbidity and mortality.

6 Jun 2023

Recovery from addiction is a journey. There’s no one-and-done solution.

The atmosphere inside the Allen House is easygoing as residents circulate freely through the hallways, meet in group sessions, or gather on a large outdoor patio that features a dirt volleyball court with an oversize net.

6 Jun 2023

Is there radiographic evidence of premature brain aging in individuals with type 1 diabetes?

Researchers identified brain regions most affected in middle-aged and older adults with type I diabetes.

6 Jun 2023

How does tirzepatide stimulate insulin secretion?

Tirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to activate two different mechanisms the body uses to control insulin secretion and energy balance, Duke Health researchers report.

6 Jun 2023

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

According to the federal government's National Institute of Neurological Disorders and Stroke, nearly 3 million people worldwide - with almost a third in the United States - are living with multiple sclerosis (MS), a disabling neurological disease in which the body's immune system mistakenly attacks nerves feeding information to the central nervous system (the brain and spinal cord). Although rarely fatal, MS can lead to long-term disabilities, and impair movement, muscle control, vision and cognition.

6 Jun 2023

New meta-analysis explores the link between adult alexithymia and all forms of child maltreatment

Have you ever wanted to convey a feeling but just couldn't find the right words? Millions of people struggle with a personality trait known as alexithymia, which means "no words for feelings."

5 Jun 2023

Study assesses the safety, efficacy of using immune checkpoint inhibitors in patients with advanced kidney cancer

Patients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment.

5 Jun 2023

Therapy News and Research

UVA scientists discover a key determinant of multiple sclerosis risk

The HEART Clinic keeps rehab within the reach for stroke, Parkinson’s patients

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

How do antibiotics affect the ecology of the gut microbiome?

Elucidating developmentally sensitive mechanisms of cognitive behavioral therapy

New strategy to grow and measure how tumor organoids respond to therapy

Oral semaglutide outperforms other medications in type 2 diabetes treatment, significantly reducing HbA1c and body weight

New insight from patients on what helps or hinders medication-assisted opioid use disorder treatment

Low-carb breakfast tames glucose spikes in type 2 diabetes

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

New folate-targeting magnetic microrobot system shows great potential in cancer treatment

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

Two studies seek to understand the drivers of chronic and progressive phase of COVID-19

Recovery from addiction is a journey. There’s no one-and-done solution.

Is there radiographic evidence of premature brain aging in individuals with type 1 diabetes?

How does tirzepatide stimulate insulin secretion?

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

New meta-analysis explores the link between adult alexithymia and all forms of child maltreatment

Study assesses the safety, efficacy of using immune checkpoint inhibitors in patients with advanced kidney cancer

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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