Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

New antibody design may pave way for treating diseases affecting the brain

Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier.

16 Jan 2017

Study finds that T cells play important role in control of Zika infections

The worst of the global Zika virus outbreak may be over but many key questions remain, such as why the virus persists in certain tissues after the systemic infection has cleared; how does the immune system counteract the virus and protect against reinfection; what determines the likelihood of long-term complications?

12 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Research findings could lead to development of novel therapeutic approaches against viral infections

Life is a question of balance, and the body is no exception. Expression levels of certain proteins can affect the immune system's ability to neutralize a virus.

12 Jan 2017

MUSC scientists design novel antibody-based therapy to fight against cancer

Scientists at the Medical University of South Carolina (MUSC) have designed an antibody-based therapy that could target the functions of TGF-beta that cause cancer

12 Jan 2017

Researchers discover how deficiency of IgM antibodies can lead to increased risk of arteriosclerosis

Following a blood infection, the first class of antibodies produced by the immune system are IgM antibodies.

9 Jan 2017

Scientists develop 3-D organoid to unravel immune response during infection

What if you could design an adaptable, biomaterials-based model of an organ to track its immune response to any number of maladies, including cancer, transplant rejection and the Zika virus? The lab of Ankur Singh, assistant professor in the Sibley School of Mechanical and Aerospace Engineering, has asked - and begun to answer - that very question.

6 Jan 2017

Scientists find new treatment option for rare autoimmune disease

Anti-NMDA receptor encephalitis is an inflammatory disease that affects the central nervous system.

6 Jan 2017

Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutations needed to enable the immune system to recognize and attack malignant cells.

6 Jan 2017

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

Investigators at the National Institutes of Health and international colleagues have identified a genetic immune disorder characterized by increased susceptibility and poor immune control of Epstein-Barr virus (EBV) and, in some cases, an EBV-associated cancer called Hodgkin's lymphoma.

23 Dec 2016

UCLA-led research finds promising results for more personalized head and neck cancer treatment

Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS-variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.

23 Dec 2016

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Scientists from the Florida campus of The Scripps Research Institute have developed an efficient process to rapidly discover new “enediyne natural products” from soil microbes that could be further developed into extremely potent anticancer drugs.

22 Dec 2016

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component.

21 Dec 2016

Researchers engineer promising live-attenuated RSV vaccine candidate

Crafting a vaccine against RSV (respiratory syncytial virus) has been a minefield for 50 years, but scientists believe they have found the right balance.

21 Dec 2016

Landmark clinical trial to test third investigational drug for Alzheimer's disease

An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer's disease.

20 Dec 2016

Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

Immunotherapy with pembrolizumab has been deemed a cost-effective first line treatment for advanced melanoma patients in Hong Kong, researchers report at the ESMO Asia 2016 Congress in Singapore.

17 Dec 2016

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Researchers at the University of California, Riverside have camels and llamas to thank for their development of a new cancer treatment that is highly selective in blocking the action of faulty matrix metalloproteinases (MMPs).

16 Dec 2016

Study suggests potential blood-based marker to predict oropharyngeal cancer recurrence

A new study suggests the possibility of predicting at its earliest stages when a type of head and neck cancer will come back.

16 Dec 2016

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

A chip developed by mechanical engineers at Worcester Polytechnic Institute can trap and identify metastatic cancer cells in a small amount of blood drawn from a cancer patient.

16 Dec 2016

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

ABIVAX an innovative biotechnology company targeting the immune system to eliminate viral disease, announced today that the Company presented new preclinical data on ABX464, ABIVAX's first-in-class drug candidate for a functional cure of patients with HIV/AIDS, during this week's HIV DART scientific conference in Los Cabos, Mexico.

9 Dec 2016

Antibody News and Research

Further Reading

New antibody design may pave way for treating diseases affecting the brain

Study finds that T cells play important role in control of Zika infections

Could pathogen infection really lead to Alzheimer’s?

Research findings could lead to development of novel therapeutic approaches against viral infections

MUSC scientists design novel antibody-based therapy to fight against cancer

Researchers discover how deficiency of IgM antibodies can lead to increased risk of arteriosclerosis

Scientists develop 3-D organoid to unravel immune response during infection

Scientists find new treatment option for rare autoimmune disease

Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

UCLA-led research finds promising results for more personalized head and neck cancer treatment

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Researchers engineer promising live-attenuated RSV vaccine candidate

Landmark clinical trial to test third investigational drug for Alzheimer's disease

Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Study suggests potential blood-based marker to predict oropharyngeal cancer recurrence

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

ABIVAX reports preclinical data on first-in-class drug candidate for functional cure of HIV/AIDS patients

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