Transplant News and Research

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Donor age has no affect on long-term liver transplant survival

A new study on the effect of donor age on survival and recurrence of hepatitis C after liver transplantation found that it influenced short-term survival, but had no long-term effect.

22 Mar 2005

Alcohol relapse adversely affects liver transplant survival

A new study on how alcohol relapse affects survival rates after liver transplants found that it adversely affected survival rates only after 10 years. The decrease in survival rates may, however, be due to other alcohol-related diseases.

22 Mar 2005

New study to evaluate Pegasys and Copegus to treat hepatitis C in liver transplant patients

Roche has initiated a new study to evaluate treatment strategies to reduce post-transplant recurrence of hepatitis C infection with the most prescribed hepatitis C treatment combination in the U.S., Pegasys (peginterferon alfa-2a) and Copegus (ribavirin, USP).

21 Mar 2005

Research to improve bone marrow transplant outcomes

The National Marrow Donor Program (NMDP) and its affiliate, the Center for International Blood and Marrow Transplant Research (CIMBTR), are supporting clinical trials to determine the best unrelated marrow and blood cell transplant procedures for patients and donors.

21 Mar 2005

Cancer survival comes at its own price

Patients who hear the dreaded words "you have cancer" invariably look forward to the day the doctor tells them "you're cured." But University of Florida researchers say survival often comes at its own price -- the mind may need mending even after the body heals.

16 Mar 2005

Heart valve transplant through leg quicker and benefits high risk cases

An experimental procedure marks the launch of a research study approved by the Food and Drug Administration in January. The breakthrough technology could save the lives of thousands of people with heart valve disease who have no other treatment options. In a new clinical trial the first U.S. patient has received a heart valve implant without open-heart surgery.

15 Mar 2005

Link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein

Researchers at the University of Pennsylvania School of Medicine have identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein known to be expressed in a number of EBV-associated cancers.

15 Mar 2005

Study indicates need for new standards and training for cornea transplants

Improving the training and standardizing the procedures used by the nation's eye banks to assess corneal cells may help to select corneas with optimal health for transplantation, according to new study led by Jonathan H. Lass, MD, principal investigator of the study and chairman of the Department of Ophthalmology at University Hospitals of Cleveland and Case Western Reserve University School of Medicine.

14 Mar 2005

You can no longer make the argument that transplanting a kidney into an older recipient is a wasted organ

Growing evidence suggests that age alone shouldn't prevent older adults from being organ donors – or having a kidney transplant themselves – according to researchers at Wake Forest University Baptist Medical Center.

14 Mar 2005

Overlapping signals in embryo help get the backbone right

A major step in the development of the vertebrate embryo - the establishment of a back that morphs into a brain, spinal cord and muscles - turns out to be so important that the body uses at least three signals to make sure it happens properly.

9 Mar 2005

Diabetes "cured" by transplant

61-year-old businessman and community activist, Richard Lane, has become Britain's first fully successful islet cell transplant recipient.

9 Mar 2005

System for producing embryonic stem cells which markedly reduces the risk of contamination with pathogens

A.C.T. Holdings and Advanced Cell Technology, Inc. (ACT) reported the first derivation of human embryonic stem cells in completely feeder-layer-free and serum-free conditions.

8 Mar 2005

Suitcase-sized machine helps patients undergoing rigorous dialysis for kidney failure

A suitcase-sized machine tested at the Indiana University School of Medicine is making life easier for some patients undergoing rigorous dialysis for kidney failure.

7 Mar 2005

Large hole in boy's liver repaired using innovative catheterization procedure

Through an innovative catheterization procedure, a pediatric cardiologist at Texas Children's Heart Center in Houston repaired a severe liver condition in a 14-year-old male.

7 Mar 2005

New therapeutic targets in liver diseases

Many patients with liver diseases often encounter difficulties with therapy and ultimately require liver transplant to survive. Since many acute and chronic liver diseases are driven by immune-mediated mechanisms, there is a necessity to find new therapies that can inhibit these immune-based triggers and block liver damage.

6 Mar 2005

Mutations in newly discovered gene, NPHP5 cause Senior-Loken syndrome

Scientists at the University of Michigan Medical School have discovered a gene called NPHP5 and found mutations in this gene that cause a rare genetic disease called Senior-Loken syndrome. Children with this syndrome develop a type of cystic kidney disease called nephronophthisis, as well as a form of blindness called retinitis pigmentosa.

3 Mar 2005

U.S. cancer researchers launch first American-Israeli cancer conference

Leading cancer researchers from Baltimore, Miami and New Jersey have organized the first Joint American-Israeli Conference on Cancer. The meeting, scheduled for March 16 through 18 in Jerusalem, seeks to foster collaboration among physicians and scientists in the two countries.

1 Mar 2005

Small hearts make big difference for young transplant recipients

When a young child is in need of a heart transplant, the problem is not the intricate surgery, but the scarcity of donors.

1 Mar 2005

Up to 500,000 Americans will develop lupus-related kidney disease

According to the Lupus Foundation of America, an estimated 300,000 to 500,000 Americans with the autoimmune disease lupus eventually will develop lupus-related kidney disease, known as lupus nephritis. Lupus nephritis is one of the most serious manifestations of lupus and can lead to serious health problems, kidney failure, disability or death.

27 Feb 2005

NIH awards grant to explore causal relationship between epoetin dose and survival of hemodialysis patients

The National Institutes of Health, National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) has awarded a two-year grant to the Medical Technology and Practice Patterns Institute (MTPPI) in collaboration with Harvard School of Public Health (HSPH) to explore the causal relationship between epoetin dose and survival of hemodialysis patients receiving this therapy.

27 Feb 2005