Laboratory News and Research

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Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

Mechanical engineering and materials science professor David Needham has shown that a slight increase in solution pH might be all it takes to turn a metabolic inhibiting drug, traditionally used to treat gut parasites, into a promising prophylactic/preventative nasal spray and early treatment throat spray for COVID-19.

7 Jan 2022

N95 respirators can be safely re-used up to 25 times after VHP decontamination

N95 respirators are commonly used in hospitals worldwide to protect healthcare personnel from infectious pathogens. During the COVID-19 pandemic, healthcare facilities have experienced shortages of the respirators, forcing personnel to re-use them or resort to less protective masking alternatives.

7 Jan 2022

Novel rehabilitation approach shows promise for recovering upper limb control in stroke patients

It happens that, after lying for a while in a way that puts pressure on a nerve in your arm, you do not feel the arm anymore, you cannot perceive its location and size, and it feels like it does not belong to your own body.

7 Jan 2022

Omicron variant found to be much less sensitive to neutralizing antibodies than Delta

The Omicron variant was detected for the first time in South Africa in November 2021 and has since spread to many countries.

7 Jan 2022

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

The current study was based on merged results using the CDD’s surveillance database coupled with the Vaccine Adverse Event Reporting System (VAERS), along with reports from health departments or physicians to the CDC.

7 Jan 2022

Integrating Microplate Evaporators with Liquid Handling Robots

The Ultravap® Mistral family of microplate evaporators from Porvair Sciences are used in labs worldwide to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from 12- to 384-well microplates and vials up to 15cm tall.

From Porvair Sciences Limited 7 Jan 2022

Scrapping many Covid testing measures is a grave mistake, says London Medical Laboratory

London Medical Laboratory warns that its testing reveals nearly one in five people still have insufficient Covid antibodies.

7 Jan 2022

Bacterial biofilms use a developmental patterning mechanism seen in plants and animals

Over the past several years, research from University of California San Diego biologist Gürol Süel's laboratory has uncovered a series of remarkable features exhibited by clusters of bacteria that live together in communities known as biofilms.

7 Jan 2022

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

In a recently published article in the journal Nano-Micro Letters, scientists have provided an in-depth review on the application and benefits of nanotechnology in the development of coronavirus disease 2019 (COVID-19) vaccines.

7 Jan 2022

COVID-19 vaccines effective at varying intensities of SARS-CoV-2 exposure

Researchers investigate the effectiveness of COVID-19 vaccines in individuals at high risk due to their proximity with infected individuals.

6 Jan 2022

Researchers explore consequences of eroding norms over release of self-spreading viruses

Decades of research by generations of virologists have generally established that the use laboratory-modified self-spreading viruses is too unpredictable to be applied safely outside of contained facilities.

6 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

Research may pave the way for designing new therapies to combat schistosomiasis

Neglected tropical diseases (NTDs) represent a group of about 20 conditions that affect more than a billion people worldwide.

6 Jan 2022

PLOS and CSHL expand partnership to offer new options for sharing preprints in medicine

The Public Library of Science (PLOS) and Cold Spring Harbor Laboratory (CSHL) today announced an expansion of their longstanding partnership to offer authors more options for rapidly and easily sharing their research before publication in a journal.

6 Jan 2022

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

Regular smokers are at heightened risk of developing cardiovascular disease, but crushing the butts in favor of a "smokeless" alternative like chewing tobacco, snuff or tobacco lozenges may go a long way toward bringing the danger down to a more normal level, a new UCLA-led study shows.

6 Jan 2022

Salk professor receives $1.2 million from Larry L. Hillblom Foundation for diabetes research

Professor Ronald Evans will receive $1.2 million over four years as part of a Network Grant from the Larry L. Hillblom Foundation to examine a molecular pathway that regulates blood sugar and fat independent of insulin.

6 Jan 2022

Streamlined, efficient approaches to cell culture spectrometry and analysis

As demand for the high throughput production of high quality, highly specialized and reliable cell culture products continues to rise, laboratories and manufacturers need to move away from traditional manual analysis methods in favor of advanced real-time analysis using power spectroscopic methods.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 6 Jan 2022

New engineered nanomaterials help capture chemotherapy drugs to avoid tissue damage

Standard chemotherapies may efficiently kill cancer cells, but they also pose significant risks to healthy cells, resulting in secondary illness and a diminished quality of life for patients. To prevent the previously unavoidable damage, researchers, led by Penn State, have developed a new class of nanomaterials engineered to capture chemotherapy drugs before they interact with healthy tissue.

6 Jan 2022

Anti-fogging sprays and cloths may contain high levels of PFAS, finds study

The anti-fogging sprays and cloths many people use to prevent condensation on their eyeglasses when wearing a mask or face shield may contain high levels of per- and polyfluorinated alkyl substances (PFAS), a new Duke University-led study finds.

5 Jan 2022

Laboratory News and Research

Slight pH adjustment may turn a metabolic inhibiting drug into promising COVID-19 treatment

N95 respirators can be safely re-used up to 25 times after VHP decontamination

Novel rehabilitation approach shows promise for recovering upper limb control in stroke patients

Omicron variant found to be much less sensitive to neutralizing antibodies than Delta

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

Integrating Microplate Evaporators with Liquid Handling Robots

Scrapping many Covid testing measures is a grave mistake, says London Medical Laboratory

Bacterial biofilms use a developmental patterning mechanism seen in plants and animals

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

COVID-19 vaccines effective at varying intensities of SARS-CoV-2 exposure

Researchers explore consequences of eroding norms over release of self-spreading viruses

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Research may pave the way for designing new therapies to combat schistosomiasis

PLOS and CSHL expand partnership to offer new options for sharing preprints in medicine

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

Salk professor receives $1.2 million from Larry L. Hillblom Foundation for diabetes research

Streamlined, efficient approaches to cell culture spectrometry and analysis

New engineered nanomaterials help capture chemotherapy drugs to avoid tissue damage

Anti-fogging sprays and cloths may contain high levels of PFAS, finds study

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