Transplant News and Research

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First implant of cryopreserved osteoarticular allograft

CryoLife, a biomaterials and biosurgical device company, announced today that a patient received the first Cryopreserved osteoarticular (OA) allograft transplant for resurfacing articular cartilage in the knee.

23 Feb 2005

Pitt researcher presents findings on when to accept organ transplants

A transplant is the only option for someone with end-stage liver disease, but patients face difficult questions when choosing the best time to receive a transplant.

20 Feb 2005

Biochemical marker aids prognosis in liver transplant patients

A new study on whether the model used to identify patients most in need of a liver transplant can be improved upon found that measuring serum sodium in potential transplant patients helps to better predict those with a poor prognosis.

20 Feb 2005

Massachusetts support of stem cell research

The Massachusetts Medical Society, the statewide association of physicians with some 18,000 members, has offered testimony before the Joint Committee on Economic Development and Emerging Technologies in support of Senate Bill 25, An Act Promoting Stem Cell Research.

17 Feb 2005

Discovery may have implications for the treatment of hemophilia A and B

University of North Carolina at Chapel Hill researchers have made a discovery that may have implications for the treatment of liver-based genetic defects such as hemophilia A and B in humans.

15 Feb 2005

Older heart transplant recipients fare just as well as their younger counterparts

Policy makers who use age as a discriminating factor in determining eligibility for heart transplant surgery may want to reconsider their rules in the light of new research at the University of Alberta.

14 Feb 2005

Level of immune cell DNA in the blood might help predict success of stem cell transplantation

Measuring the quantity of a certain type of immune cell DNA in the blood could help physicians predict whether a bone marrow stem cell transplant will successfully restore a population of infection-fighting cells called T lymphocytes in a child.

7 Feb 2005

Risks of obesity in children with kidney transplants

Obese children who get kidney transplants tend to be younger, shorter and on dialysis longer than their leaner peers, according to a study in the February issue of the journal Pediatrics.

7 Feb 2005

Gene therapy helps generate bone around dental implants

A University of Michigan research team has found that introducing a growth factor protein into a mouth wound using gene therapy helped generate bone around dental implants, according to a new paper in the February issue of the journal Molecular Therapy.

3 Feb 2005

Bioartificial kidney containing billions of donor kidney cells under study at the Medical College of Georgia

Whether a bioartificial kidney containing billions of donor kidney cells will help intensive care patients with kidney failure survive is under study at the Medical College of Georgia.

31 Jan 2005

Genzyme files Glucocerebrosidase patent infringement

Genzyme announced today that it has filed a lawsuit in the District Court of Tel Aviv alleging that Transkaryotic Therapies Inc. has infringed Genzyme's Israeli patent No. 100,715, which covers certain cell culture processes involved in the manufacture of glucocerebrosidase.

25 Jan 2005

Available lines of human embryonic stem cells have been contaminated

Currently available lines of human embryonic stem cells have been contaminated with a non-human molecule that compromises their potential therapeutic use in human subjects, according to research by investigators at the University of California, San Diego (UCSD) School of Medicine and the Salk Institute in La Jolla, California.

24 Jan 2005

Severity of liver disease not a reliable indicator of quality of life

A new study on the determination of how livers are allocated for transplants examined the relationship between liver disease severity and quality of life, and found that the commonly used model for liver allocation is not a reliable indicator of general quality of life.

24 Jan 2005

Cord blood transplantation now a viable option for adult leukemia patients

Stem cell transplantation using umbilical cord blood is a standard treatment option for blood disorders in children, but not for adults, due to the difficulty of obtaining a sufficiently large dose of cells.

20 Jan 2005

Rotary blood pump shows promise for pediatric patients

Ventricular assist devices (VADs), blood pumps used in heart failure situations, now have the potential for use in additional patient groups. Scientists and clinicians gathered at the 11th Congress of the International Society of Rotary Blood Pumps in Germany last year to discuss past lessons learned and future directions for this technology.

10 Jan 2005

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Millennium Pharmaceuticals today announced, in collaboration with Johnson & Johnson Pharmaceutical Research & Development, LLC, the initiation of VISTA (Velcadeas Initial Standard Therapy in multiple myeloma: Assessment with melphalan and prednisone), a multicenter, international phase III clinical trial of Velcadein combination with melphalan and prednisone versus melphalan and prednisone in patients with newly diagnosed multiple myeloma (MM) who are not transplant candidates.

10 Jan 2005

Medical device innovations - fabricating the future

Two large pieces of metal lie on the floor of what looks like a mini-factory in the Cleveland Clinic’s Lerner Research Institute. The whirring machinery here stamps out prototypes of medical devices imagined by clinicians and researchers to help with diagnostic testing or surgical procedures.

9 Jan 2005

Potential cure for lymphoma in HIV patients

Stem cell transplants have become the standard of care for patients with relapsed lymphoma, but not for patients who suffer from both this disease and HIV.

7 Jan 2005

New hope for millions of patients suffering from liver damage (cirrhosis)

Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant.

5 Jan 2005

Gene therapy effective in helping children with severe combined immunodeficiency (SCID)

A UK study in this week’s issue of THE LANCET provides further evidence that gene therapy can be effective in creating a functional immune system for infants with severe combined immunodeficiency (SCID).

20 Dec 2004