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Researchers study molecular elements effective in fighting malaria

The scientists research a building block of organic molecules needed for medical chemistry development. Spirocycles in nature is an element, that chemists are crazy about. This element presents in artemisinin, the most effective group of drugs against malaria.

21 Dec 2019

Inhibition of a single enzyme may reduce heparin-induced thrombocytopenia

Heparin is widely used as an anticoagulant, but evokes in some patients a potentially life-threatening condition called HIT. Clinical scientists at Ludwig-Maximilians-Universitaet in Munich have now shown that inhibition of a single enzyme may markedly reduce this risk.

21 Dec 2019

Genomic data can accurately and reliably predict stroke risk

Estimates based on genomic data predict stroke risk with an accuracy similar to, or greater than those based on clinical risk factors. This result implies that persons at high risk might benefit from more rigorous preventive measures.

21 Dec 2019

California AG details ‘historic’ settlement agreement in Sutter Health antitrust case

Sutter Health will pay $575 million to settle a closely watched antitrust case filed by California Attorney General Xavier Becerra, whose office had accused the nonprofit health care giant of using its market dominance in Northern California to illegally drive up prices.

20 Dec 2019

Researchers take first step to find causes of sarcopenia

Researchers have gained new insight into the mechanisms involved in how skeletal muscles lose their mass and strength as people age, called sarcopenia.

20 Dec 2019

Scientists successfully cultivate and characterize corpus luteum cells of cats

The reproduction of lynxes is highly mysterious. Unlike other wild cats, most lynxes are only receptive for a few days once a year.

20 Dec 2019

Artificial intelligence can detect AML with high reliability

Artificial intelligence can detect one of the most common forms of blood cancer - acute myeloid leukemia (AML) - with high reliability.

20 Dec 2019

New 'tumor-on-a-chip' can be used to find better cancer fighting drugs

Kyoto University researchers have developed a new 'tumor-on-a-chip' device that can better mimic the environment inside the body, paving the way for improved screening of potential cancer-fighting drugs.

20 Dec 2019

Researchers develop powerful computer algorithm for large-scale genomic analysis

Haplotypes are a set of genetic variations that, located side by side on the same chromosome, are transmitted in a single group to the next generation. Their examination makes it possible to understand the heritability of certain complex traits, such as the risk of developing a disease.

20 Dec 2019

Kobe scientists develop mathematical model to predict cancer drug side effects

A research team at Kobe University Hospital have further illuminated the likelihood of cancer drug side effects that can occur due to genetic mutations in the drug-metabolizing enzyme.

20 Dec 2019

Researchers locate brain biomarkers for detecting Alzheimer's disease

From the detection of functional brain changes that occur during Alzheimer's Disease, a research team from the Complutense University of Madrid has located a set of biomarkers that could predict which patients with Mild Cognitive Impairment have a higher risk of developing dementia.

20 Dec 2019

A receptor helps body cells to spot communication amongst bacteria

Bacterial infection does not automatically lead to illness; many germs only become dangerous when they occur in large numbers.

20 Dec 2019

Could high cholesterol lead to motor neuron disease?

Researchers suggest that motor neuron disease may be linked to an abnormal build-up of cholesterol and other lipids within cellular compartments.

20 Dec 2019

Target at-risk patients for prostate cancer screening, say experts

Almost one in six deaths from prostate cancer could be prevented if targeted screening was used for men at a higher genetic risk for the disease.

20 Dec 2019

p53 may play a more important role in kidney cancer than previously thought

The p53 gene, which researchers had thought was less relevant in kidney cancer, may play an important role after all – a discovery that could lead to new treatments.

20 Dec 2019

Scientists identify molecular mechanisms that protect cells against mechanical stress

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified the molecular mechanisms that allow our cells to adapt to, protect themselves against, and survive mechanical stress.

20 Dec 2019

Combined datasets can expedite the discovery and development of new cancer drugs

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types.

20 Dec 2019

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

p53 is the most famous cancer gene, not least because it's involved in causing over 50% of all cancers. When a cell loses its p53 gene -- when the gene becomes mutated -- it unleashes many processes that lead to the uncontrolled cell growth and refusal to die, which are hallmarks of cancer growth.

20 Dec 2019

A veteran started vaping THC to cope with chronic pain. Then he got very sick.

As vaping has grown more popular in recent years, the trend has been fueled by the habit’s pleasurable allure: Compared with smoking cigarettes or pot, vaping is discreet and less smelly. Vaping fluids come in hundreds of flavors. There’s no tar or other byproducts of burning. And vape pens are high-tech, customizable and sleek.

20 Dec 2019

New genetic score is similar or more predictive than common risk factors for stroke

A group of investigators from Australia, Germany, and the UK have shown that genetic data obtained from a single blood draw or saliva sample can be used to identify individuals at a 3-fold increased risk of developing ischemic stroke, a devastating condition and one of the leading causes of disability and death world-wide.

20 Dec 2019

Research News and Research

Researchers study molecular elements effective in fighting malaria

Inhibition of a single enzyme may reduce heparin-induced thrombocytopenia

Genomic data can accurately and reliably predict stroke risk

California AG details ‘historic’ settlement agreement in Sutter Health antitrust case

Researchers take first step to find causes of sarcopenia

Scientists successfully cultivate and characterize corpus luteum cells of cats

Artificial intelligence can detect AML with high reliability

New 'tumor-on-a-chip' can be used to find better cancer fighting drugs

Researchers develop powerful computer algorithm for large-scale genomic analysis

Kobe scientists develop mathematical model to predict cancer drug side effects

Researchers locate brain biomarkers for detecting Alzheimer's disease

A receptor helps body cells to spot communication amongst bacteria

Could high cholesterol lead to motor neuron disease?

Target at-risk patients for prostate cancer screening, say experts

p53 may play a more important role in kidney cancer than previously thought

Scientists identify molecular mechanisms that protect cells against mechanical stress

Combined datasets can expedite the discovery and development of new cancer drugs

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

A veteran started vaping THC to cope with chronic pain. Then he got very sick.

New genetic score is similar or more predictive than common risk factors for stroke

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