Biochemistry News and Research

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New protein identified as substrate for histidine methylation

Proteins are subject to post-translational chemical modifications that result in functional diversity. Methylation is one such modification that is generally believed to occur on lysine and arginine residues.

29 Sep 2023

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

28 Sep 2023

Discovery sheds new light on the chain of events in early embryonic development

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development.

27 Sep 2023

Arrayed CRISPR Screening for Revolutionizing Target Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Kuenzel, Associate Director in the Functional Genomics department at AstraZeneca about the application of arrayed CRISPR screening for target identification and more.

From Society for Laboratory Automation and Screening (SLAS) 27 Sep 2023

$45M awarded to develop sense-and-respond implant technology for cancer treatment

The Advanced Research Projects Agency for Health (ARPA-H) has awarded $45 million to rapidly develop sense-and-respond implant technology that could slash U.S. cancer-related deaths by more than 50%.

26 Sep 2023

Gene-silencer study could pave the way for novel cancer therapeutics

Deep inside our cells - each one complete with an identical set of genes - a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

26 Sep 2023

Pitt launches trial to test interventions for life-threatening bleeding in injured children

The No. 1 cause of death in children is trauma. There are an estimated 2,000 pediatric deaths from traumatic bleeding in the U.S. each year that are preventable with optimal care, yet there have been no large-scale clinical trials to guide the best way to resuscitate children with life-threatening bleeding from traumatic injury.

21 Sep 2023

Scientists uncover a crucial component for restoring functional activity after spinal cord injury

In a new study in mice, a team of researchers from UCLA, the Swiss Federal Institute of Technology, and Harvard University have uncovered a crucial component for restoring functional activity after spinal cord injury.

21 Sep 2023

A family of weird proteins hijacks plants’ cellular plumbing

Many of the bacteria that ravage crops and threaten our food supply use a common strategy to cause disease: they inject a cocktail of harmful proteins directly into the plant's cells.

13 Sep 2023

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Researchers at the University of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting.

12 Sep 2023

Capture and release of tumor cells using a bioelectronic device

In the book entitled Microfluidic Systems for Cancer Diagnosis, the UPV/EHU’s Microfluidics Cluster group describes the process for building a bioelectronic device consisting of gold electrodes coated with a smart polymer capable of capturing and releasing cells in a non-invasive, controllable way while monitoring the processes using conventional electrical measurements.

8 Sep 2023

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Vibrant green leaves sprout from tall fragrant plants sitting neatly in two rows of terracotta pots in Valerie Sponsel's UTSA biology laboratory.

8 Sep 2023

CMFI 2023: Advancing the fight against multi-resistant pathogens

CMFI 2023 addresses pressing challenges of our time, such as the rise of multi-resistant pathogens and the roles of microbes in causing or preventing major chronic disease.

5 Sep 2023

Coronavirus fusion peptide could be important target for vaccine development

Although the COVID-19 pandemic was the first time most of humanity learned of the now infamous disease, the family of coronaviruses was first identified in the mid-1960s.

4 Sep 2023

Lessons learned from COVID-19 pandemic can help confront future epidemics

Where did COVID-19 originate? Prof Angus Dalgleish shows that the virus that emerged in Wuhan, China in 2019 had been modified in a laboratory to make it more infectious (for the construction of a more effective vaccine).

1 Sep 2023

Discovery could lead to more effective treatments for cancers

Case Western Reserve University biochemical researchers have identified a new function of a key protein that leads to cancer–a finding they believe could lead to more effective treatments for a range of cancers and other diseases.

31 Aug 2023

New insights into how lung cells detect influenza virus

Researchers from Trinity College Dublin have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses.

31 Aug 2023

Coronavirus fusion peptide plays more invasive role in infection than previously thought

Although the COVID-19 pandemic was the first time most of humanity learned of the now infamous disease, the family of coronaviruses was first identified in the mid-1960s.

31 Aug 2023

Scientists discover new microglial population important for memory and learning

Following more than seven years of research, researchers at the University of Seville-IBiS (Institute of Biomedicine of Seville) have identified a new key cell type with a critical role in the developmental processes of memory and learning.

31 Aug 2023

New omicron variants can reinfect people who were infected with earlier variants

The omicron variants of the SARS-CoV-2 virus, which have rapidly spread around the world over the past year, latch onto our cells more tightly, invade them more efficiently, and elude many of the antibodies induced by previous infections and vaccines.

30 Aug 2023

Biochemistry News and Research

New protein identified as substrate for histidine methylation

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Discovery sheds new light on the chain of events in early embryonic development

Arrayed CRISPR Screening for Revolutionizing Target Discovery

$45M awarded to develop sense-and-respond implant technology for cancer treatment

Gene-silencer study could pave the way for novel cancer therapeutics

Pitt launches trial to test interventions for life-threatening bleeding in injured children

Scientists uncover a crucial component for restoring functional activity after spinal cord injury

A family of weird proteins hijacks plants’ cellular plumbing

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Capture and release of tumor cells using a bioelectronic device

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

CMFI 2023: Advancing the fight against multi-resistant pathogens

Coronavirus fusion peptide could be important target for vaccine development

Lessons learned from COVID-19 pandemic can help confront future epidemics

Discovery could lead to more effective treatments for cancers

New insights into how lung cells detect influenza virus

Coronavirus fusion peptide plays more invasive role in infection than previously thought

Scientists discover new microglial population important for memory and learning

New omicron variants can reinfect people who were infected with earlier variants

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