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New findings on how hepatitis C survives for so long in the body

Researchers at the University of Leeds have discovered a previously unknown mechanism that allows the hepatitis C virus (HCV) to remain in the body for decades.

18 Aug 2009

Additional trial to be conducted for KYNAPID under FDA special protocol agreement

Cardiome Pharma Corp. (NASDAQ: CRME/TSX: COM) and its co-development partner Astellas Pharma US, Inc. ("Astellas") announced today that Astellas will undertake a single confirmatory additional Phase 3 clinical trial of KYNAPID(TM) (vernakalant hydrochloride) Injection for rapid conversion of atrial fibrillation to sinus rhythm. The trial, to be called ACT 5, is expected to begin enrolling patients by the end of 2009, with completion expected in the first half of 2011.

11 Aug 2009

Smoking provokes migraine attacks

Tobacco acts as a precipitating factor for headaches, specifically migraines. This is indicated in a study which shows that smokers have more migraine attacks and that smoking more than five cigarettes a day triggers this headache. The work has appeared in The Journal of Headache and Pain.

24 Jun 2009

Discovery of molecular defect involved in hearing loss

Scientists from The Scripps Research Institute have elucidated the action of a protein, harmonin, which is involved in the mechanics of hearing.

13 May 2009

New anticonvulsant compound prevents seizure progression in model of epilepsy

Carnegie Mellon University researchers have identified a new anticonvulsant compound that has the potential to stop the development of epilepsy. The findings are published in the March issue of the journal Epilepsia.

4 May 2009

New target for the treatment of depression

An acid-sensitive protein in the brain may represent a new target for the treatment of depression, according to animal research in the April 29 issue of The Journal of Neuroscience.

30 Apr 2009

New sequencing technique looks at medical potential of King Kong toxin

King Kong toxin, a component of the venom in some poisonous marine snails, has a peculiar power to go with its peculiar name.

29 Apr 2009

Discovery of ion channel turns ear on its head

Scientists thought they had a good model to explain how the inner ear translates vibrations in the air into sounds heard by the brain.

23 Apr 2009

Researchers study why people who are obese become hypertensive

When Francois Abboud began his work at the University of Iowa in 1960, little was known about the constant physiological chatter between the brain and the blood vessels.

22 Apr 2009

A nanoscale motor in the ear

Utah and Texas researchers have learned how quiet sounds are magnified by bundles of tiny, hair-like tubes atop "hair cells" in the ear: when the tubes dance back and forth, they act as "flexoelectric motors" that amplify sound mechanically.

22 Apr 2009

Alzheimer's controversy solved

For a decade, Alzheimer's disease researchers have been entrenched in debate about one of the mechanisms believed to be responsible for brain cell death and memory loss in the illness.

15 Apr 2009

Researchers show how PCBs may alter in utero, neonatal brain development

In three new studies - including one appearing online in the Public Library of Science - Biology (PLoS - Biology) - UC Davis researchers provide compelling evidence of how low levels of polychlorinated biphenyls (PCBs) alter the way brain cells develop.

13 Apr 2009

Common gene variations found to influence risk factor for sudden cardiac death

A new study has identified several common genetic variants related to a risk factor for sudden cardiac death.

23 Mar 2009

Phylonix granted broad U.S. patent for assessing cardiac functions in Zebrafish

Phylonix Pharmaceuticals announced, at the Society of Toxicology Annual Meeting in Baltimore, that the U.S. Patent and Trademark Office has issued the company a broad patent for assessing the toxicity of pharmaceutical test agents on cardiovascular functions in zebrafish.

15 Mar 2009

New insights on heart's 'fight or flight' response to stress

Even for those without a heart condition, it's a peculiar feeling when your heart "races" in response to stress.

10 Mar 2009

Experimental drug fampridine improves mobility for some MS patients

In MS, the body's immune system attacks myelin, a fatty tissue that wraps and insultates nerve fibers, disrupting the transmission of signals in the central nervous system.

1 Mar 2009

Compounds that trigger beta cell replication identified

Researchers at the Genomics Institute of the Novartis Research Foundation (GNF) have identified a set of compounds that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques.

25 Feb 2009

Oxford Nanopore announces publication of DNA analysis paper

Oxford Nanopore Technologies ("Oxford Nanopore") today announced the publication of new research in Nature Nanotechnology, demonstrating accurate and continuous identification of DNA bases using nanopores.

From Oxford Nanopore Technologies 23 Feb 2009

Experimental antiarrhythmic drug dronedarone reduces death rate in patients with atrial fibrillation

Results from the ATHENA trial, reported in the 12th February issue of the New England Journal of Medicine , suggest that the (as yet unlicensed) antiarrhythmic drug dronedarone can reduce the incidence of cardiovascular-related hospitalisation or death in patients with atrial fibrillation.

16 Feb 2009

Boosting its infectivity turns benign virus into good gene therapy carrier for cystic fibrosis

Researchers from the University of California, Berkeley, and the University of Iowa have turned a relatively benign virus into a highly infectious form that is ideal as a carrier for gene therapy.

16 Feb 2009